Patents by Inventor Ezra Abrams

Ezra Abrams has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210062180
    Abstract: A cassette for retaining molecules during electrophoresis has a housing with a lane configured therein. The lane has a first elongate edge and a second elongate edge, and an elution module is configured to be received in the late to divide the lane into a first chamber and a second chamber. A first buffer reservoir is positioned adjacent the first elongate edge, and a second buffer reservoir is positioned adjacent the second elongate edge. The first side of the elution module facing the first chamber comprises a porous sterile filtration membrane. The second side of the elution module facing the second chamber comprises an ultrafiltration membrane that has a pore size to retain molecules during electrophoresis.
    Type: Application
    Filed: January 4, 2019
    Publication date: March 4, 2021
    Inventors: Ezra ABRAMS, Todd J. BARBERA, Chris BOLES
  • Patent number: 9643180
    Abstract: The invention provides an improved method for sensitive and specific detection of target molecules, cells, or viruses. The inventive method uses large area imaging to detect individual labeled targets complexed with a target-specific selection moiety. The invention eliminates wash steps through the use of target-specific selection through one or more liquid layers that can contain optical dye and density agents. By eliminating washes the invention simplifies instrumentation engineering and minimizes user steps and costs. The invention uses sensitive image analysis to enumerate individual targets in a large area, is scalable, and can be deployed in systems ranging in complexity from manual to highly automated.
    Type: Grant
    Filed: September 24, 2009
    Date of Patent: May 9, 2017
    Assignee: First Light Biosciences, Inc.
    Inventors: Ezra Abrams, Sadanand Gite, Lisa Shinefeld, Don Straus, Gordon Siek, Greg Yantz
  • Publication number: 20120149007
    Abstract: The invention provides an improved method for sensitive and specific detection of target molecules, cells, or viruses. The inventive method uses large area imaging to detect individual labeled targets complexed with a target-specific selection moiety. The invention eliminates wash steps through the use of target-specific selection through one or more liquid layers that can contain optical dye and density agents. By eliminating washes the invention simplifies instrumentation engineering and minimizes user steps and costs. The invention uses sensitive image analysis to enumerate individual targets in a large area, is scalable, and can be deployed in systems ranging in complexity from manual to highly automated.
    Type: Application
    Filed: September 24, 2009
    Publication date: June 14, 2012
    Applicant: Straus Holdings Inc.
    Inventors: Ezra Abrams, Sadanand Gite, Lisa Shinefeld, Don Straus, Gordon Siek, Greg Yantz
  • Publication number: 20050079519
    Abstract: Methods of detecting target molecules using electrophoresis and media containing immobilized capture are described.
    Type: Application
    Filed: July 9, 2004
    Publication date: April 14, 2005
    Inventors: Truett Boles, Andrew Muir, Stephen Kron, Ezra Abrams