Abstract: The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.

Abstract: The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.

Abstract: The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.

Abstract: The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.

Abstract: The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.

Abstract: The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.

Abstract: The present invention relates to sulfonamides, pharmaceutical compositions containing them, and their use as antagonists of urotensin II.

Abstract: Arbitration of multiple transponders, such as RFID tags, occurs in an interrogation field. The arbitration process is custom-tailored for individual applications, under software control, by the transponder reader or tag reader. Different wake-up slots are calculated for each tag during successive transmission cycles based upon the tag ID and the transmission cycle number. The tag reader may also send a special command to a tag to read its data and cause the tag to become decoupled from the environment. The tags may be selectively placed in either a tag-talk-first mode or a reader-talk-first mode. Furthermore, the tag reader may send a special fast read command to the tag which includes a read request and at least one parameter of the read request.

Abstract: An optical path for voice, video, and data transmission, and methods for manufacturing optical cables for use in optical transmission systems. The optical path or sub-paths have linearly and or non-linearly length dependant parameters which may have mutual relationships, for which local selection criteria allows a minimally restrictive local selection.

Abstract: This invention is directed to oxoazaheterocycyl compounds which inhibit Factor Xa, to oxoazaheterocycyl compounds which inhibit both Factor Xa and Factor IIa, to pharmaceutical compositions comprising these compounds, to intermediates useful for preparing these compounds, to a method of directly inhibiting Factor Xa and to a method of simultaneously directly inhibiting Factor Xa and Factor IIa..

Abstract: The present invention provides systems and methods for implementing variable financial plans. The methods can include identifying an account, and accessing an account planning tool. Characteristics associated with the account are presented to the account planning tool, and an account plan is developed using the planning tool. Based at least in part on the account plan, a funds transfer is facilitated from a source of funds to the account. Activity in the account is monitored, and the account plan is modified in response to activity detected in the account plan.

Abstract: The present invention provides systems and methods for customizing fixed rate and variable rate mortgages. In some cases, the methods include accessing mortgage information and identifying at least a first characteristic of the mortgage to be modified. In addition, a first funds transfer is authorized to facilitate modification of the first characteristic. The mortgage is also monitored and changes in any relevant characteristics are identified. Where changes in a second relevant characteristic is detected, a second funds transfer is authorized to facilitate modification of the first characteristic to compensate for the change in the second characteristic.

Abstract: A radio frequency identification (RFID) tag device having a pulse position modulation (PPM) decoder circuit which calculates a relative frequency relationship between an internal clock-oscillator of the RFID tag device and an external PPM source such as a RFID tag reader, and then synchronizes the RFID tag device PPM decoder circuit to the required precision for reliable PPM symbol decoding. The PPM decoder is synchronized by measuring the “counts per pulse” (CPP) from a calibration cycle having a plurality of pulses in a single symbol frame.

Abstract: This invention is directed to an (aminoiminomethyl or aminomethyl)benzoheteroaryl compound of formula I which is useful for inhibiting the activity of Factor Xa by combining said compound with a composition containing Factor Xa. The present invention is also directed to compositions containing compounds of the formula I, methods for their preparation, their use, such as in inhibiting the formation of thrombin or for treating a patient suffering from, or subject to, a disease state associated with a physiologically detrimental excess amount of thrombin.

Abstract: This invention is directed to an (aminoiminomethyl or aminomethyl)benzoheteroaryl compound of formula I which is useful for inhibiting the activity of Factor Xa by combining said compound with a composition containing Factor Xa. The present invention is also directed to compositions containing compounds of the formula I, methods for their preparation, their use, such as in inhibiting the formation of thrombin or for treating a patient suffering from, or subject to, a disease state associated with a physiologically detrimental excess amount of thrombin.

Abstract: This invention relates to the novel amino substituted pyrimidine compounds of Formulas (I), (II) and (III), and pharmaceutical compositions comprising a compound of these Formulas and a pharmaceutically acceptable diluent or carrier. This invention also relates to a method of inhibiting CSBP kinase and cytokines mediated by this kinase, for the treatment of cytokine mediated diseases, in mammals, by administration of a compound of Formula (I), (II) or (III).

Abstract: This invention relates to drug binding proteins, to genes encoding same and to assays and methods for screening pharmaceuticals. More specifically, this invention relates to a Cytokine Suppressive Anti-Inflammatory Drug (CSAID) binding protein, to a gene encoding same and to assays and screens useful in the evaluation and characterization of drugs of this pharmacologic class.

Abstract: A rotating field antenna is provided which includes a figure eight shape loop, a center loop magnetically coupled to the figure eight shape loop, and a drive element for driving the figure eight loop. The figure eight shape loop has an upper loop, a lower loop and a crossover region therebetween. The center loop overlaps at least a portion of the crossover region and at least a portion of one or both of the upper and lower loops. The center loop has no direct or physical electrical connection to the offset figure eight shape loop. Magnetic induction produces a 90-degree phase difference between the phase of the figure eight loop and the phase of the center loop. The antenna thereby produces a rotating composite field when driven by the drive element. The figure eight loop and the center loop are coplanar. The drive element may be an amplified voltage source which has a fundamental frequency of about 13.

Abstract: This invention relates to the novel amino substituted pyrimidine compounds of Formulas (I), (II) and (III), and pharmaceutical compositions comprising a compound of these Formulas and a pharmaceutically acceptable diluent or carrier.This invention also relates to a method of inhibiting CSBP kinase and cytokines mediated by this kinase, for the treatment of cytokine mediated diseases, in mammals, by administration of a compound of Formula (I), (II) or (III).

Abstract: An RFID tag circuit provides magnetic decoupling and amplitude modulation. The circuit is made up of a first inductor and a second inductor connected in series, a first capacitor, a second capacitor, and a switch. The circuit includes a first resonant circuit formed from a parallel connection of the series connected first and second inductors, and the first capacitor. The first resonant circuit has a primary resonant frequency. The circuit also includes a second circuit formed from a series connection of the second capacitor and the switch. The series connection of the second capacitor and the switch are connected in parallel to the second inductor. One end of the series connected second capacitor and switch is connected to the common connection between the series connected first and second inductors.