Patents by Inventor F. Joseph Daugherty

F. Joseph Daugherty has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230414690
    Abstract: Methods for preparing compositions highly enriched in phenolic compounds from plant materials that naturally contain phenolic compounds such as anthocyanins and proanthocyanidins are enriched for a wide spectrum of phenolic compounds and consist of phenolic compounds including monomers, dimers, trimers, oligomers and polymers >3000 amu and over 35% concentrated total phenols. The compositions of the present disclosure which include phenolic compounds including monomers, dimers, trimers, oligomers and polymers >3000 amu and over 35% concentrated total phenols optionally include trisodium citrate and/or cyclodextrin.
    Type: Application
    Filed: June 22, 2023
    Publication date: December 28, 2023
    Applicant: Phenolics, LLC
    Inventors: Michael S. Tempesta, F. Joseph Daugherty
  • Publication number: 20230055210
    Abstract: Formulations of creatine, preferably phosphocreatine and most preferably disodium phosphocreatine, combined with cyclodextrin exhibit improved uptake across digestive mucosa, including intestinal, esophageal, and stomach mucosa. In particular, the formulations of the present invention are designed for protection of the creatine as they come in contact with gastric juices so as to allow thereafter for unexpectedly improved site-specific intestinal release.
    Type: Application
    Filed: October 21, 2022
    Publication date: February 23, 2023
    Applicant: Phenolics, LLC
    Inventors: Michael S. Tempesta, F. Joseph Daugherty
  • Publication number: 20220338519
    Abstract: Oral supplements containing phenolic compounds such as those present in Vaccinium and/or Sambucus, as well as other genera are enriched in total phenols and combined with either organic acid sodium salts and/or phosphocreatine salts are shown to have enhanced absorption properties. When taken together in an oral supplement, the particular phenolic compound(s) found in such extracts and in other genera containing significant quantities of total phenols are believed to enhance the activity of the phosphocreatine salts in a synergistic manner and result in enhancement of physical activity as well as provide recovery from inflammation.
    Type: Application
    Filed: April 8, 2022
    Publication date: October 27, 2022
    Applicant: Phenolics, LLC
    Inventors: F. Joseph Daugherty, Michael S. Tempesta
  • Publication number: 20220211729
    Abstract: Formulations of creatine, preferably phosphocreatine and most preferably disodium phosphocreatine, combined with cyclodextrin exhibit improved uptake across digestive mucosa, including intestinal, esophageal, and stomach mucosa. In particular, the formulations of the present invention are designed for protection of the cyclodextrin as it comes in contact with gastric juices so as to allow thereafter for unexpectedly improved site-specific intestinal release.
    Type: Application
    Filed: April 23, 2019
    Publication date: July 7, 2022
    Inventors: MICHAEL S. TEMPESTA, F. JOSEPH DAUGHERTY
  • Publication number: 20220112256
    Abstract: A composition for eliciting a T-cell mediated immune response in a subject includes transfer factor from at least two different types of source animals. For example, the composition may include mammalian transfer factor and nonmammalian transfer factor. An example of the composition includes a combination of a colostrum-derived product, which includes the mammalian transfer factor, and an egg-derived product, which includes the nonmammalian transfer factor. Additionally, the egg-derived product may be substantially free of fat. Methods for forming the composition and eliciting T-cell mediated immune responses in subjects that have been treated with the composition are also disclosed.
    Type: Application
    Filed: December 21, 2021
    Publication date: April 14, 2022
    Inventors: David Lisonbee, William J. Hennen, F. Joseph Daugherty
  • Patent number: 11246846
    Abstract: The present invention relates to formulations of certain amino acids, peptides and similar molecules in combination with trisodium citrate exhibiting improved bioavailability and enhanced uptake across digestive mucosa. The present invention relates particularly to formulation of trisodium citrate in combinations with leucine, iso-leucine, valine, arginine, sarcosine, glutathione, carnosine, glucosamine, creatine, protein hydrolysates and/or gamma-aminobutyric acid exhibiting improved uptake across digestive mucosa. More particularly, the improved uptake across digestive mucosa takes place across intestinal, esophageal and/or stomach mucosa.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: February 15, 2022
    Inventors: Michael S. Tempesta, F. Joseph Daugherty
  • Patent number: 11203625
    Abstract: A composition for eliciting a T-cell mediated immune response in a subject includes transfer factor from at least two different types of source animals. For example, the composition may include mammalian transfer factor and nonmammalian transfer factor. An example of the composition includes a combination of a colostrum-derived product, which includes the mammalian transfer factor, and an egg-derived product, which includes the nonmammalian transfer factor. Additionally, the egg-derived product may be substantially free of fat. Methods for forming the composition and eliciting T-cell mediated immune responses in subjects that have been treated with the composition are also disclosed.
    Type: Grant
    Filed: November 4, 2019
    Date of Patent: December 21, 2021
    Assignee: 4LIFE PATENTS, LLC
    Inventors: David Lisonbee, William J. Hennen, F. Joseph Daugherty
  • Publication number: 20210361731
    Abstract: The oral supplements of the present invention utilize phenolic compounds in combination with creatine, choline, and trisodium citrate, wherein when taken together result in enhanced cellular permeation in comparison to cellular permeation in the absence of the other compounds of the combination leading to improved brain and/or physical functioning.
    Type: Application
    Filed: May 20, 2021
    Publication date: November 25, 2021
    Applicant: Phenolics, LLC
    Inventors: F. Joseph Daugherty, Michael S. Tempesta
  • Publication number: 20200397729
    Abstract: The present invention relates to formulations of certain amino acids, peptides and similar molecules in combination with trisodium citrate exhibiting improved bioavailability and enhanced uptake across digestive mucosa. The present invention relates particularly to formulation of trisodium citrate in combinations with leucine, iso-leucine, valine, arginine, sarcosine, glutathione, carnosine, glucosamine, creatine, protein hydrolysates and/or gamma-aminobutyric acid exhibiting improved uptake across digestive mucosa. More particularly, the improved uptake across digestive mucosa takes place across intestinal, esophageal and/or stomach mucosa.
    Type: Application
    Filed: October 22, 2018
    Publication date: December 24, 2020
    Inventors: MICHAEL S. TEMPESTA, F. JOSEPH DAUGHERTY
  • Publication number: 20200062815
    Abstract: A composition for eliciting a T-cell mediated immune response in a subject includes transfer factor from at least two different types of source animals. For example, the composition may include mammalian transfer factor and nonmammalian transfer factor. An example of the composition includes a combination of a colostrum-derived product, which includes the mammalian transfer factor, and an egg-derived product, which includes the nonmammalian transfer factor. Additionally, the egg-derived product may be substantially free of fat. Methods for forming the composition and eliciting T-cell mediated immune responses in subjects that have been treated with the composition are also disclosed.
    Type: Application
    Filed: November 4, 2019
    Publication date: February 27, 2020
    Inventors: David Lisonbee, William J. Hennen, F. Joseph Daugherty
  • Patent number: 10464980
    Abstract: A composition for eliciting a T-cell mediated immune response in a subject includes transfer factor from at least two different types of source animals. For example, the composition may include mammalian transfer factor and nonmammalian transfer factor. An example of the composition includes a combination of a colostrum-derived product, which includes the mammalian transfer factor, and an egg-derived product, which includes the nonmammalian transfer factor. Additionally, the egg-derived product may be substantially free of fat. Methods for forming the composition and eliciting T-cell mediated immune responses in subjects that have been treated with the composition are also disclosed.
    Type: Grant
    Filed: March 15, 2006
    Date of Patent: November 5, 2019
    Assignee: 4Life Patents, LLC
    Inventors: David Lisonbee, F. Joseph Daugherty
  • Patent number: 10231933
    Abstract: An oral creatine formulation includes soluble creatine and polyethylene glycol, coated with an enteric coating. The most preferred soluble creatine is creatine HCl. The most preferred polyethylene glycols have an average molecular weight of from 3150 to 3685, although for particular formulation formulations and particular uses, the average molecular weight polyethylene glycols may range from 190 to 9000.
    Type: Grant
    Filed: April 20, 2010
    Date of Patent: March 19, 2019
    Assignee: CRYXA LLC
    Inventors: F. Joseph Daugherty, John R. Palmer, Michael S. Tempesta
  • Patent number: 10226429
    Abstract: An oral creatine formulation includes soluble creatine and polyethylene glycol, coated with an enteric coating. The most preferred soluble creatine is creatine HCl. The most preferred polyethylene glycols have an average molecular weight of from 3150 to 3685, although for particular formulation formulations and particular uses, the average molecular weight polyethylene glycols may range from 190 to 9000.
    Type: Grant
    Filed: April 20, 2010
    Date of Patent: March 12, 2019
    Assignee: CRYXA LLC
    Inventors: F. Joseph Daugherty, John R. Palmer, Jr., Michael S. Tempesta
  • Publication number: 20100203131
    Abstract: An oral creatine formulation includes soluble creatine and polyethylene glycol, coated with an enteric coating. The most preferred soluble creatine is creatine HCl. The most preferred polyethylene glycols have an average molecular weight of from 3150 to 3685, although for particular formulation formulations and particular uses, the average molecular weight polyethylene glycols may range from 190 to 9000.
    Type: Application
    Filed: April 20, 2010
    Publication date: August 12, 2010
    Inventors: F. Joseph Daugherty, John R. Palmer, JR., Michael S. Tempesta
  • Publication number: 20100203090
    Abstract: An oral creatine formulation includes soluble creatine and polyethylene glycol, coated with an enteric coating. The most preferred soluble creatine is creatine HCl. The most preferred polyethylene glycols have an average molecular weight of from 3150 to 3685, although for particular formulation formulations and particular uses, the average molecular weight polyethylene glycols may range from 190 to 9000.
    Type: Application
    Filed: April 20, 2010
    Publication date: August 12, 2010
    Inventors: F. Joseph DAUGHERTY, John R. Palmer, JR., Michael S. Tempesta
  • Patent number: 7682637
    Abstract: A product made by a process which results in compositions enriched in total phenols includes purification steps not involving the addition of bisulfite ions. The enriched compositions are characterized as containing monomeric, oligomeric and polymeric phenols, total phenol concentration >12% and exhibiting in vitro COX-2 inhibitory activity enhanced by a factor of at least 2.5 over a standard aspirin dose of 660 ?g/mL.
    Type: Grant
    Filed: August 7, 2007
    Date of Patent: March 23, 2010
    Assignee: Phenolics, LLC
    Inventors: Gerald T. Gourdin, Steven L. Richheimer, Michael S. Tempesta, David T. Bailey, Rebecca L. Nichols, F. Joseph Daugherty, Delano R. Freeberg
  • Publication number: 20090306209
    Abstract: Oral amino acid formulations comprising polyethylene glycol are enteric coated. Most preferred amino acids are leucine, glutamine, and arginine. The most preferred polyethylene glycols have an average molecular weight of from 3150 to 3685, although for particular formulation formulations and particular uses, the average molecular weight polyethylene glycols may range from 190 to 9000.
    Type: Application
    Filed: June 3, 2009
    Publication date: December 10, 2009
    Inventors: F. Joseph DAUGHERTY, Michael S. TEMPESTA
  • Publication number: 20090099373
    Abstract: This invention provides compositions enriched for anthocyanins and methods of preparation thereof from a crude plant extract. The method of preparation includes a novel column purification step using a brominated polystyrene resin.
    Type: Application
    Filed: October 30, 2008
    Publication date: April 16, 2009
    Applicant: PHENOLICS, LLC
    Inventors: David T. BAILEY, Delano R. Freeberg, Dennis Gertenbach, Gerald T. Gourdin, Steven L. Richheimer, Michael S. Tempesta, F. Joseph Daugherty
  • Publication number: 20090035226
    Abstract: Cranberry and other plant extracts enriched in total phenols and free or substantially free of sugars, acids, sulfur and other contaminants are used for periodontal treatments. The periodontal treatments of the present invention include swish and swallow techniques, in which the extracts enriched in total phenols but free or substantially free of sugars, acids, sulfur and other contaminants, are solubilized in water or other solvent, placed in the mouth, swished around the teeth and then swallowed. Other application techniques include gel applications, gum formulations and toothpaste formulations.
    Type: Application
    Filed: July 31, 2008
    Publication date: February 5, 2009
    Applicant: PHENOLICS, LLC
    Inventors: Michael S. TEMPESTA, F. Joseph Daugherty
  • Publication number: 20080306159
    Abstract: An oral creatine formulation includes soluble creatine and polyethylene glycol, coated with an enteric coating. The most preferred soluble creatine is creatine HCl. The most preferred polyethylene glycols have an average molecular weight of from 3150 to 3685, although for particular formulation formulations and particular uses, the average molecular weight polyethylene glycols may range from 190 to 9000.
    Type: Application
    Filed: June 4, 2008
    Publication date: December 11, 2008
    Inventors: F. Joseph Daugherty, John R. Palmer, JR., Michael S. Tempesta