Patents by Inventor F. Peter Charleson

F. Peter Charleson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High affinity chelates containing isothiocyanate groups, useful for coupling with peptides and proteins
    Patent number: 5539138
    Abstract: The ligands HBED-SCN, HBPD-SCN, and HTDD-SCN are provided which have enhanced ease of reaction with peptides or proteins and which are suitable for chelating with radioisoptopes, especially Indium-.sup.III and Gallium-.sup.67.
    Type: Grant
    Filed: July 28, 1994
    Date of Patent: July 23, 1996
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Richard J. Flanagan, Keith T. Hogan, Jean-Marc Dufour, F. Peter Charleson
  • Chelate derivatives of atrial natriuretic factor (ANF)
    Patent number: 5248764
    Abstract: Derivatives of synthetic fragments of mammalian atrial natriuretic factor (ANF) in which a chelate molecule is attached to the N-terminal of the peptide are described. The chelate component allows the facile labelling of these peptides with metallic isotopes such as Tc-99m, Ga-67, In-111 and others. These radioactive chelates are useful in determining the in vivo behavior and fate of derivatives of ANF.
    Type: Grant
    Filed: February 27, 1992
    Date of Patent: September 28, 1993
    Assignee: Merck Frosst Canada, Inc.
    Inventors: Richard J. Flanagan, F. Peter Charleson
  • Stabilized radiopharmaceutical compositions
    Patent number: 4880615
    Abstract: Radiolytic decomposition of a radiopharmaceutical compositions containing radioactive iodine are stabilized by the incorporation therein of an effective amount of ascorbic acid, nicotinamide, nicotinic acid or combinations thereof.
    Type: Grant
    Filed: November 25, 1988
    Date of Patent: November 14, 1989
    Assignee: Merck & Co., Inc.
    Inventor: F. Peter Charleson