Patents by Inventor F. Randall Grimes

F. Randall Grimes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210041440
    Abstract: Methods and apparatus for identifying disease status according to various aspects of the present invention include analyzing the levels of one or more biomarkers. The methods and apparatus may use biomarker data for a condition-positive cohort and a condition-negative cohort and select multiple relevant biomarkers from the plurality of biomarkers. The system may generate a statistical model for determining the disease status according to differences between the biomarker data for the relevant biomarkers of the respective cohorts. The methods and apparatus may also facilitate ascertaining the disease status of an individual by producing a composite score for an individual patient and comparing the patient's composite score to one or more thresholds for identifying potential disease status.
    Type: Application
    Filed: January 28, 2020
    Publication date: February 11, 2021
    Inventor: F. Randall Grimes
  • Publication number: 20110077931
    Abstract: Methods and apparatus for identifying disease status according to various aspects of the present invention include analyzing the levels of one or more biomarkers. The methods and apparatus may use biomarker data for a condition-positive cohort and a condition-negative cohort and select multiple relevant biomarkers from the plurality of biomarkers. The system may generate a statistical model for determining the disease status according to differences between the biomarker data for the relevant biomarkers of the respective cohorts. The methods and apparatus may also facilitate ascertaining the disease status of an individual by producing a composite score for an individual patient and comparing the patient's composite score to one or more thresholds for identifying potential disease status.
    Type: Application
    Filed: December 7, 2010
    Publication date: March 31, 2011
    Inventor: F. Randall Grimes
  • Publication number: 20070254369
    Abstract: Methods and apparatus for identifying disease status according to various aspects of the present invention include analyzing the levels of one or more biomarkers such as riboflavin carrier protein (RCP). The methods and apparatus may process the biomarker data, for example by normalizing the RCP concentration data. The RCP data may be used to detect diseases, such as cancer.
    Type: Application
    Filed: February 28, 2007
    Publication date: November 1, 2007
    Inventors: F. RANDALL GRIMES, Donald F. Weber
  • Patent number: 6824521
    Abstract: A microminiature sensing module and a sensing catheter system are provided. The module includes a sensor and signal conditioning circuit mounted on a substrate having electrical contacts positioned to facilitate connection of the module to an electrical bus, such as a dual lead electrical bus. The catheter system incorporates a dual lead electrical bus and one or more sensor modules. Methods of fabricating sensing catheter systems are also provided.
    Type: Grant
    Filed: January 22, 2002
    Date of Patent: November 30, 2004
    Assignee: Integrated Sensing Systems, Inc.
    Inventors: Collin A. Rich, F. Randall Grimes
  • Publication number: 20020156417
    Abstract: A microminiature sensing module and a sensing catheter system are provided. The module includes a sensor and signal conditioning circuit mounted on a substrate having electrical contacts positioned to facilitate connection of the module to an electrical bus, such as a dual lead electrical bus. The catheter system incorporates a dual lead electrical bus and one or more sensor modules. Methods of fabricating sensing catheter systems are also provided.
    Type: Application
    Filed: January 22, 2002
    Publication date: October 24, 2002
    Inventors: Collin A. Rich, F. Randall Grimes
  • Patent number: 6327069
    Abstract: Electrochromic devices and processes for preparing the same are provided which do not require a separate process step of ion intercalation by employing an electrochromically-inert reducing or oxidizing additive in the electrochemically active material or the electrolyte of the electrochromic devices.
    Type: Grant
    Filed: November 8, 1999
    Date of Patent: December 4, 2001
    Assignee: Donnelly Corporation
    Inventors: Pierre-Marc Allemand, Barbara A. Bigelow, F. Randall Grimes, Anoop Agrawal
  • Patent number: 5989717
    Abstract: Electrochromic devices and processes for preparing the same are provided which do not require a separate process step of ion intercalation by employing an electrochromically-inert reducing or oxidizing additive in the electrochemically active material or the electrolyte of the electrochromic devices.
    Type: Grant
    Filed: July 8, 1998
    Date of Patent: November 23, 1999
    Assignee: Donnelly Corporation
    Inventors: Pierre-Marc Allemand, Barbara A. Bigelow, F. Randall Grimes, Anoop Agrawal
  • Patent number: 5780160
    Abstract: Electrochromic devices and processes for preparing the same are provided which do not require a separate process step of ion intercalation by employing an electrochromically-inert reducing or oxidizing additive in the electrochemically active material or the electrolyte of the electrochromic devices.
    Type: Grant
    Filed: October 26, 1994
    Date of Patent: July 14, 1998
    Assignee: Donnelly Corporation
    Inventors: Pierre-Marc Allemand, Barbara A. Bigelow, F. Randall Grimes, Anoop Agrawal
  • Patent number: 5729379
    Abstract: An electrochromic device is disclosed having a conducting electrode opposing a counter conducting electrode with an electrochemically active polymeric layer disposed on an opposing surface of one of said electrodes and an electrolyte containing at least one redox active material contactingly disposed between the electrochemically active layer and an other opposing surface of one of said electrodes, wherein at least one of the electrodes is transparent. Also disclosed is an electrochromic device that exhibits low light transmission or reflectivity with no applied potential or after removal of an applied potential.
    Type: Grant
    Filed: October 24, 1995
    Date of Patent: March 17, 1998
    Assignee: Donnelly Corporation
    Inventors: Pierre-Marc Allemand, F. Randall Grimes, Anoop Agrawal, Barbara A. Bigelow, Andrew R. Ingle