Patents by Inventor F. Timothy Guilford

F. Timothy Guilford has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8679530
    Abstract: The invention proposes the sure of reduced glutathione in a liposome (liposomal reduced glutathione) for the oral administration of a therapeutically effective amount to ameliorate the progression of vascular disease, including atherosclerosis, diabetes, hypertension, narrowing of arteries leading to decreased blood flow, ischemic events, and the formation of blood clots, abnormal platelet aggregation, and thrombotic events, by reducing the amount and effect of oxidized cholesterol, oxidized HDL and oxidized LDL. The invention also proposes combining liposomal encapsulated glutathione with statin drugs to improve the effect of lowering not only cholesterol but also the oxidized cholesterol as well as oxidized HDL and oxidized LDL. The invention also proposes combining liposomal encapsulated glutathione with CoQ10 as a therapy for vascular disease and management of side effects of statin therapy.
    Type: Grant
    Filed: October 26, 2006
    Date of Patent: March 25, 2014
    Assignee: Your Energy Systems, LLC
    Inventors: F. Timothy Guilford, Brooke Schumm, III
  • Patent number: 8349359
    Abstract: The invention is a composition administrable orally to provide systemic glutathione (reduced) and a method for providing systemic glutathione by oral administration of glutathione (reduced) in a liposome encapsulation. The administration of a therapeutically effective amount of oral liposomal glutathione (reduced) results in improvement of symptoms in disease states related to glutathione deficiency such as Parkinson's disease and cystic fibrosis. Compounds enhancing the effect of the liposomal glutathione are contemplated such as Selenium, EDTA, carbidopa, and levodopa.
    Type: Grant
    Filed: November 6, 2005
    Date of Patent: January 8, 2013
    Assignee: Your Energy Systems, LLC
    Inventors: F. Timothy Guilford, Brian Charles Keller
  • Publication number: 20120219616
    Abstract: The invention enables management of mammalian disease related to decreased energy production in the mitochondria by a combination of liposomal reduced glutathione and 1-arginine. For individuals whose inability to lose weight is related to inefficiency of the biochemical pathways facilitating mitochondrial function and energy production, the invention proposes to assist in weight loss by improving the inefficient production of energy by the respiratory transport chain of mitochondria. The invention is useful for the management of the metabolic syndrome, a group of metabolic factors associated with an increased risk of vascular disease problems. The invention is also useful for the resolution of fatigue that accompanies both weight gain and illnesses. The ability of the invention to increase the production of the biochemical agmatine in the central nervous system as well as generally in the body is part of the benefit of the combination of liposomal reduced glutathione and 1-arginine.
    Type: Application
    Filed: February 8, 2012
    Publication date: August 30, 2012
    Applicant: YOUR ENERGY SYSTEMS, LLC
    Inventors: F. Timothy Guilford, Brian C. Keller
  • Patent number: 8252325
    Abstract: The invention is a composition administrable orally to provide systemic glutathione (reduced) and a method for providing systemic glutathione by oral administration of glutathione (reduced) in a liposome encapsulation. The administration of a therapeutically effective amount of oral liposomal glutathione (reduced) results in improvement of symptoms in disease states related to glutathione deficiency such as Parkinson's disease and cystic fibrosis. Compounds enhancing the effect of the liposomal glutathione are contemplated such as Selenium, EDTA, carbidopa, and levodopa.
    Type: Grant
    Filed: February 15, 2012
    Date of Patent: August 28, 2012
    Assignee: Your Energy Systems, LLC
    Inventors: F. Timothy Guilford, Brian C. Keller
  • Publication number: 20120141608
    Abstract: The invention is for the combination and related methods of N-acetyl-cysteine oral, inhaled, or intravenous, or glutathione inhaled or intravenous, generally in combination with antibiotic and/or antiviral therapy to ameliorate the toxic effects of infection with materials used in Bioterror incidents such as Bacillus anthracis and smallpox virus, and alternatively, upon exposure to radiation, during testing, and vaccination, as treatment prior to treatment with antibiotic or antiviral therapy to ameliorate the toxic effects of infection and exposure with these organisms.
    Type: Application
    Filed: June 18, 2009
    Publication date: June 7, 2012
    Inventors: F. Timothy GUILFORD, Brooke SCHUMM, III
  • Publication number: 20120135068
    Abstract: The invention is a composition administrable orally to provide systemic glutathione (reduced) and a method for providing systemic glutathione by oral administration of glutathione (reduced) in a liposome encapsulation. The administration of a therapeutically effective amount of oral liposomal glutathione (reduced) results in improvement of symptoms in disease states related to glutathione deficiency such as Parkinson's disease and cystic fibrosis. Compounds enhancing the effect of the liposomal glutathione are contemplated such as Selenium, EDTA, carbidopa, and levodopa.
    Type: Application
    Filed: February 15, 2012
    Publication date: May 31, 2012
    Inventors: F. Timothy Guilford, Brian C. Keller
  • Publication number: 20120087994
    Abstract: The invention is for the combination and related methods of N-acetyl-cysteine oral, inhaled, or intravenous, or glutathione inhaled or intravenous, generally in combination with antibiotic and/or antiviral therapy to ameliorate the toxic effects of infection with materials used in Bioterror incidents such as Bacillus anthracis and smallpox virus, and alternatively, upon exposure to radiation, during testing, and vaccination, as treatment prior to treatment with antibiotic or antiviral therapy to ameliorate the toxic effects of infection and exposure with these organisms.
    Type: Application
    Filed: December 19, 2011
    Publication date: April 12, 2012
    Inventors: F. Timothy Guilford, Brooke Schumm, III
  • Patent number: 8147869
    Abstract: The invention is a composition administrable orally to provide systemic glutathione (reduced) and a method for providing systemic glutathione by oral administration of glutathione (reduced) in a liposome encapsulation. The administration of a therapeutically effective amount of oral liposomal glutathione (reduced) results in improvement of symptoms in disease states related to glutathione deficiency such as Parkinson's disease and cystic fibrosis. Compounds enhancing the effect of the liposomal glutathione are contemplated such as Selenium, EDTA, carbidopa, and levodopa.
    Type: Grant
    Filed: August 31, 2011
    Date of Patent: April 3, 2012
    Assignee: Your Energy Systems, LLC
    Inventors: F. Timothy Guilford, Brian C. Keller
  • Patent number: 8114913
    Abstract: The invention is for the combination and related methods of N-acetyl-cysteine oral, inhaled, or intravenous, or glutathione inhaled or intravenous, generally in combination with antibiotic and/or antiviral therapy to ameliorate the toxic effects of infection with materials used in Bioterror incidents such as Bacillus anthracis and smallpox virus, and alternatively, upon exposure to radiation, during testing, and vaccination, as treatment prior to treatment with antibiotic or antiviral therapy to ameliorate the toxic effects of infection and exposure with these organisms.
    Type: Grant
    Filed: June 18, 2009
    Date of Patent: February 14, 2012
    Assignee: Your Energy Systems, LLC
    Inventors: F. Timothy Guilford, Brooke Schumm, III
  • Publication number: 20120021073
    Abstract: The invention is for the combination and related methods of N-acetyl-cysteine oral, inhaled, or intravenous, or glutathione inhaled or intravenous, generally in combination with antibiotic and/or antiviral therapy to ameliorate the toxic effects of infection with materials used in Bioterror incidents such as Bacillus anthracis and smallpox virus, and alternatively, upon exposure to radiation, during testing, and vaccination, as treatment prior to treatment with antibiotic or antiviral therapy to ameliorate the toxic effects of infection and exposure with these organisms.
    Type: Application
    Filed: June 18, 2009
    Publication date: January 26, 2012
    Inventors: F. Timothy GUILFORD, Brooke SCHUMM, III
  • Publication number: 20110305752
    Abstract: The invention is a composition administrable orally to provide systemic glutathione (reduced) and a method for providing systemic glutathione by oral administration of glutathione (reduced) in a liposome encapsulation. The administration of a therapeutically effective amount of oral liposomal glutathione (reduced) results in improvement of symptoms in disease states related to glutathione deficiency such as Parkinson's disease and cystic fibrosis. Compounds enhancing the effect of the liposomal glutathione are contemplated such as Selenium, EDTA, carbidopa, and levodopa.
    Type: Application
    Filed: August 31, 2011
    Publication date: December 15, 2011
    Inventors: F. Timothy GUILFORD, Brian C. KELLER
  • Publication number: 20110129523
    Abstract: The invention proposes the sure of reduced glutathione in a liposome (liposomal reduced glutathione) for the oral administration of a therapeutically effective amount to ameliorate the progression of vascular disease, including atherosclerosis, diabetes, hypertension, narrowing of arteries leading to decreased blood flow, ischemic events, and the formation of blood clots, abnormal platelet aggregation, and thrombotic events, by reducing the amount and effect of oxidized cholesterol, oxidized HDL and oxidized LDL. The invention also proposes combining liposomal encapsulated glutathione with statin drugs to improve the effect of lowering not only cholesterol but also the oxidized cholesterol as well as oxidized HDL and oxidized LDL. The invention also proposes combining liposomal encapsulated glutathione with CoQ10 as a therapy for vascular disease and management of side effects of statin therapy.
    Type: Application
    Filed: October 26, 2006
    Publication date: June 2, 2011
    Inventors: F. Timothy Guilford, Brooke Schumm, III
  • Publication number: 20110020436
    Abstract: The invention is a topical therapeutically effective amount of melatonin encapsulated in a liposome applied topically to an area of skin affected by immunologic response, radiation treatment induced dermatitis, acne, insect bite or other irritant stimulus such as sunburn in order to reduce itching. The invention also proposes a topical therapeutically effective amount of melatonin and reduced glutathione encapsulated in a liposome applied topically to an area of skin for relief of those afflictions.
    Type: Application
    Filed: October 6, 2010
    Publication date: January 27, 2011
    Inventor: F. Timothy Guilford
  • Publication number: 20100316700
    Abstract: The invention is for the combination and related methods of liposomal reduced glutathione in oral, inhaled, or intravenous, or glutathione inhaled or intravenous, to ameliorate the effects of exposure to or ingestion of radiation or radioactive materials, as treatment to ameliorate the toxic effects of radiation exposure or ingestion and to facilitate the decorporation of radioactive materials such as Co-60. The invention may also be used in conjunction with a decorporation agent such as DTPA, EDTA, DMPS or penicillamine to ameliorate the toxic effects of exposure or ingestion of radioactive agents or other toxic metals.
    Type: Application
    Filed: February 8, 2010
    Publication date: December 16, 2010
    Inventor: F. Timothy Guilford
  • Publication number: 20100291196
    Abstract: The invention proposes the use of reduced glutathione encapsulated in a liposome (liposomal reduced glutathione) for the oral administration of a therapeutically effective amount to improve symptoms in disease states related to diminished function of the methylation pathway such as autism, other neurodegenerative diseases and abnormalities of neurotransmitter levels in urine or blood. The invention also proposes combining liposomal encapsulated methylcobalamin, and/or liposomal encapsulated Insulin Growth Factor 1 (IGF-1) with liposomal reduced glutathione to accomplish such improvement.
    Type: Application
    Filed: July 21, 2010
    Publication date: November 18, 2010
    Inventor: F. Timothy Guilford
  • Publication number: 20100233193
    Abstract: The invention is for the combination and related methods of N-acetyl-cysteine oral, inhaled, or intravenous, or glutathione inhaled or intravenous, generally in combination with antibiotic and /or antiviral therapy to ameliorate the toxic effects of infection with materials used in Bioterror incidents such as Bacillus anthracis and smallpox virus, and alternatively, upon exposure to radiation, during testing, and vaccination, as treatment prior to treatment with antibiotic or antiviral therapy to ameliorate the toxic effects of infection and exposure with these organisms.
    Type: Application
    Filed: June 18, 2009
    Publication date: September 16, 2010
    Inventors: F. Timothy Guilford, Brooke Schumm, III
  • Publication number: 20100233297
    Abstract: The invention is for the combination and related methods of N-acetyl-cysteine oral, inhaled, or intravenous, or glutathione inhaled or intravenous, generally in combination with antibiotic and/or antiviral therapy to ameliorate the toxic effects of infection with materials used in Bioterror incidents such as Bacillus anthracis and smallpox virus, and alternatively, upon exposure to radiation, during testing, and vaccination, as treatment prior to treatment with antibiotic or antiviral therapy to ameliorate the toxic effects of infection and exposure with these organisms.
    Type: Application
    Filed: June 18, 2009
    Publication date: September 16, 2010
    Inventors: F. Timothy Guilford, Brooke Schumm, III
  • Publication number: 20100166846
    Abstract: The invention relates to a composition and method for the management of myoclonus and myoclonus and other illnesses related to mold toxin exposure. The invention proposes the use of reduced glutathione encapsulated in a liposome (liposomal reduced glutathione) for the oral administration of a therapeutically effective amount to facilitate treatment of myoclonus. The oral liposomal reduced glutathione is also proposed for the removal of mold toxin and to improve symptoms in disease states related to exposure to mold toxins. The invention proposes a method of treatment combining an orally administrable preparation of liposomal glutathione with an anti-fungal agent.
    Type: Application
    Filed: December 30, 2009
    Publication date: July 1, 2010
    Inventor: F. Timothy Guilford
  • Publication number: 20090068253
    Abstract: The invention is the use of a therapeutically effective amount of glutathione (reduced) in a liposome encapsulation for oral administration to improve symptoms of illnesses that are related to viruses and for the treatment and prevention of virus, particularly HHV-6 and EBV, which liposomal encapsulation of glutathione (reduced) is referred to as liposomal glutathione. The application references specifically reduced glutathione and its importance, and how to stabilize it effectively so it can be taken orally, and need not be refrigerated. New uses for tuberculosis, and asthma are discussed. The combination is proposed of reduced glutathione and Highly Active Anti-Retroviral Therapy having at least one pharmaceutical composition selected from the group of Nucleoside/tide Reverse Transcriptase Inhibitors (NRTIs), Protease Inhibitors (PIs), and Non-nucleoside Reverse Transcriptase Inhibitors (NnRTIs).
    Type: Application
    Filed: September 6, 2006
    Publication date: March 12, 2009
    Inventor: F. Timothy Guilford
  • Publication number: 20090047340
    Abstract: The invention enables management of mammalian disease related to decreased energy production in the mitochondria, the powerhouse of the cell. The invention uses the combination of liposomal reduced glutathione and l-arginine to increase the ability weight loss in individuals with excess weight. The mechanism of weight loss appears to be related to improving the inefficient production of energy by the respiratory transport chain of mitochondria, the function of which are influenced positively by the availability of antioxidant nitric oxide in a non-oxidized environment. This invention enables weight loss in individuals who's inability to lose weight is related to inefficiency of the biochemical pathways facilitating mitochondrial function and energy production. The pathways related to inability to lose weight are also related to the phenomenon of the inability to metabolize fats, which results in insulin resistance and diabetes. The invention is useful for the management of the metabolic syndrome.
    Type: Application
    Filed: March 29, 2007
    Publication date: February 19, 2009
    Inventor: F. Timothy Guilford