Abstract: A drug delivery device (1), comprising a delivery unit (2) in the form of a disposable single-use part and a base unit (4) in the form of a reusable part for coupling to the delivery unit (2), the delivery unit comprising a liquid flow system for pumping liquid from a drug vial or cartridge (3) received in the drug delivery device to an outlet of the device for transcutaneous administration of a liquid drug, the base unit including at least a power source and an electronic control system, the delivery unit and base units comprising a releasable locking mechanism including a locking shoulder (30) on the delivery unit that engages a complementary locking shoulder (34) on the base unit.

Abstract: A drug delivery device (1), comprising a delivery unit (2) in the form of a disposable single use part and a base unit (4) in the form of a reusable part for coupling to the delivery unit (2), the delivery unit comprising a liquid flow system for pumping liquid from a drug vial or cartridge (3) received in the drug delivery device to an outlet of the device for transcutaneous administration of a liquid drug, the base unit including at least a power source and an electronic control system, the delivery unit and base units comprising a releasable locking mechanism including a locking shoulder (30) on the delivery unit that engages a complementary locking shoulder (34) on the base unit. The locking mechanism comprising an unlocking actuator that may be actuated to release the locking shoulder (30) from the complementary locking shoulder (34).

Abstract: A drug delivery device (1) having a delivery unit (3) including a drug container (6), a liquid flow system (7), a pumping system (8), and a casing (9) enclosing therein the drug container, the pumping system and at least a part of the liquid flow system is disclosed. The drug container has a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion. The drug container is contained within a container receiving cavity (75) of a container casing portion (38) and the container receiving cavity is fluidically interconnected to a fluid outlet (31) of the pumping system (8) in a gas tight manner. The pumping system pumps environmental air into the container receiving cavity (75) thus applying pressure on a back end (73) of the plunger for delivery of a liquid drug.

Abstract: A drug delivery device (1), including a delivery unit (3) comprising a subcutaneous delivery system including a needle support (10), an injection needle (9) mounted on the needle support, and an injection needle actuation mechanism configured to engage and slidably move the needle support from a retracted position where the injection needle is within a housing (2) of the drug delivery device to an extended delivery position where the injection needle projects through a skin contact wall of the housing.

Abstract: Method of producing a drug delivery device comprising a prefilled drug container (6), a fluidic pack including a liquid flow system (7) providing a fluidic connection from the drug container to a patient during a drug delivery action of the drug delivery device, a control unit comprising electronic parts, a housing (2), the method comprising the following steps: a) assembling components of the fluidic pack to form said fluidic pack, b) sterilizing the fluidic pack, c) providing said prefilled drug container, d) assembling the fluidic pack to the prefilled drug container to form a container pack system, e) assembling the container pack system to the control unit and the housing (2) to form the drug delivery device, wherein steps c) and d) are performed in aseptic conditions.

Abstract: A drug delivery device (1) comprising a delivery unit (3) including a drug container (6) in the form of a drug cartridge containing a liquid drug (78) therein, a liquid flow system (7), a pumping system (8) and a casing (9) within which the drug container (6), the pumping system (8) and at least a part of the liquid flow system (7) are mounted, the drug container comprising a septum (6c) sealing an end of the drug container, the liquid flow system (7) comprising an injection delivery system (13) including an injection needle (15) configured for injection of the drug in an actuated state of the drug delivery device.

Abstract: A drug delivery device (1), including a delivery unit (3) comprising a subcutaneous delivery system including a needle support (10), an injection needle (9) mounted on the needle support, and an injection needle actuation mechanism configured to engage and slidably move the needle support from a retracted position where the injection needle is within a housing (2) of the drug delivery device to an extended delivery position where the injection needle projects through a skin contact wall of the housing.

Abstract: A drug delivery device (1), including a delivery unit (3) comprising a subcutaneous delivery system including a needle support (10), an injection needle (9) mounted on the needle support, and an injection needle actuation mechanism configured to engage and slidably move the needle support from a retracted position where the injection needle is within a housing (2) of the drug delivery device to an extended delivery position where the injection needle projects through a skin contact wall of the housing. The delivery unit further comprises a needle shield mechanism comprising a needle shield cover (16) slidably movable from a retracted position within the housing to an extended position covering the needle and a spring (26) biasing the needle shield cover towards the extended position, the needle support comprising a shoulder engaging a shoulder of the needle shield cover configured to hold the needle shield cover in the retracted position prior to actuation of the injection needle actuation mechanism.

Abstract: Drug delivery device (1) comprising a housing (2), a delivery unit (3), a drive unit (4) and a pumping system, the delivery unit comprising a subcutaneous delivery system (6) and a needle actuator system (7), the subcutaneous delivery system comprising a slidable needle support (10) and an injection needle mounted to the slidable needle support, the needle support movable with respect to the housing (2) from a retracted position where the needle is mounted within the housing, to an extended position where the needle projects through a skin contact wall (48) of the housing for subcutaneous delivery, the needle actuator mechanism comprising an actuation disc (12) rotatably mounted to a housing portion (38) within the housing (2) configured to displace the slidable needle support from the retracted position to the extended position by rotation of the actuation disc.

Abstract: A drug delivery device (1), comprising a delivery unit (3) including a drug container (6) comprising a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion, and a drive unit (4) comprising a pneumatic flow system (74) and a pneumatic pumping system configured to pump air via the pneumatic flow system (74) to a space behind the plunger to generate a gas pressure to advance the plunger in the container during drug delivery. The drug delivery device comprises a sealing adaptor (9) mounted on an end of the drug container facing an outer side of the plunger, the sealing adaptor (9) comprising a sealing plug (23) inserted inside an end of the barrel portion, the sealing plug (23) comprising an orifice (26) configured for pluggable sealing connection to a gas channel connector (40) of the pneumatic flow system.

Abstract: A drug delivery device (1), comprising a delivery unit (3) including a drug container (6), a liquid flow system (7), a pumping system (8), and a casing (9) enclosing therein the drug container, the pumping system and at least a part of the liquid flow system, the drug container comprising a barrel portion (6a) and a plunger (12) slidably mounted within the barrel portion and sealing the drug (78) within the container at one end of the barrel portion, the liquid flow system (7) connected fluidically to the drug container during delivery of the liquid drug.

Abstract: A drug delivery device (1), comprising a delivery unit (2) in the form of a disposable single use part and a base unit (4) in the form of a reusable part for coupling to the delivery unit (2), the delivery unit comprising a liquid flow system for pumping liquid from a drug vial or cartridge (3) received in the drug delivery device to an outlet of the device for transcutaneous administration of a liquid drug, the base unit including at least a power source and an electronic control system, the delivery unit and base units comprising a releasable locking mechanism including a locking shoulder (30) on the delivery unit that engages a complementary locking shoulder (34) on the base unit. The locking mechanism comprising an unlocking actuator that may be actuated to release the locking shoulder (30) from the complementary locking shoulder (34).

Abstract: A pump including: a stator (4), a rotor (6) slidably and rotatably mounted at least partially in the stator, the rotor comprising a first axial extension (24) having a first diameter (D1) and a second axial extension (26) having a second diameter (D2) greater than the first diameter, a first valve (V1) formed by a first valve seal (18) mounted on the stator around the first axial extension, in conjunction with a first channel (42) in the rotor that is configured to allow liquid communication across the first valve seal when the first valve is in an open position, a second valve (V2) formed by a second valve seal (20) mounted on the stator around the second axial extension, in conjunction with a second channel (44) in the rotor that is configured to allow liquid communication across the second valve seal when the second valve is in an open position, and a pump chamber (8) formed between the rotor and stator and between the first valve seal and second valve seal.

Abstract: A pump including: a stator (4), a rotor (6) slidably and rotatably mounted at least partially in the stator, the rotor comprising a first axial extension (24) having a first diameter (D1) and a second axial extension (26) having a second diameter (D2) greater than the first diameter, a first valve (V1) formed by a first valve seal (18) mounted on the stator around the first axial extension, in conjunction with a first channel (42) in the rotor that is configured to allow liquid communication across the first valve seal when the first valve is in an open position, a second valve (V2) formed by a second valve seal (20) mounted on the stator around the second axial extension, in conjunction with a second channel (44) in the rotor that is configured to allow liquid communication across the second valve seal when the second valve is in an open position, and a pump chamber (8) formed between the rotor and stator and between the first valve seal and second valve seal.