Patents by Inventor Fabian Käsermann

Fabian Käsermann has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200247903
    Abstract: The invention relates to an antibody to a red blood cell for use in treating or preventing an inflammatory disorder, and to methods of treating or preventing an inflammatory disorder comprising administering to a subject in need thereof a therapeutically effective amount of an antibody to a red blood cell.
    Type: Application
    Filed: October 19, 2018
    Publication date: August 6, 2020
    Inventors: Alan Lazarus, Fabian Kaesermann, Sandra Koernig, Andrew Crow
  • Publication number: 20190119377
    Abstract: This disclosure provides recombinant IgG Fc multimers and methods of treating autoimmune and inflammatory diseases by administering such multimers.
    Type: Application
    Filed: January 27, 2017
    Publication date: April 25, 2019
    Inventors: Rolf SPIRIG, Fabian KAESERMANN, Adrian ZUERCHER, Con PANOUSIS, Adriana BAZ MORELLI, Chao-Guang CHEN
  • Patent number: 8632773
    Abstract: The present invention relates to a population of antibodies enriched from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. Furthermore, the present invention relates to a method of enriching a population of antibodies from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. The present invention also relates to the population of antibodies of the invention for use in medicine, a pharmaceutical composition comprising the populations of antibodies of the invention and the use of the population of antibodies of the invention in the prevention and/or treatment of atherosclerosis, cancer and infections such as bacterial, viral or fungal infections.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: January 21, 2014
    Assignees: CSL Behring AG, University of Washington
    Inventors: Fabian Käsermann, Monika Rüegsegger, Sylvia Miescher, Keith Elkon
  • Publication number: 20130058917
    Abstract: The invention relates to populations of antibodies obtainable by fractionation of plasma immunoglobulins, in particular plasma IgG, by affinity chromatography on a Sambucus nigra affinity column, and uses thereof.
    Type: Application
    Filed: May 4, 2011
    Publication date: March 7, 2013
    Inventors: Fabian Käsermann, Sylvia Miescher
  • Publication number: 20120009189
    Abstract: The present invention relates to a population of antibodies enriched from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. Furthermore, the present invention relates to a method of enriching a population of antibodies from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. The present invention also relates to the population of antibodies of the invention for use in medicine, a pharmaceutical composition comprising the populations of antibodies of the invention and the use of the population of antibodies of the invention in the prevention and/or treatment of atherosclerosis, cancer and infections such as bacterial, viral or fungal infections.
    Type: Application
    Filed: March 26, 2010
    Publication date: January 12, 2012
    Inventors: Fabian Käsermann, Monika Rüegsegger, Sylvia Miescher, Keith Elkon