Abstract: We describe transgenic cells which are transformed with nucleic acid molecules which encode glucosyltransferase polypeptides involved in phenylpropanoid biosynthesis.

Abstract: We describe transgenic cells which are transformed with nucleic acid molecules which encode glucosyltransferase polypeptides involved in phenylpropanoid biosynthesis.

Abstract: Provided are methods of silencing a target gene in an organism, which methods comprises the steps of: (a) providing a recombinant DNA construct including an expression cassette comprising: (i) a promoter, operably linked to, (ii) a chimeric nucleotide sequence encoding all or part of the target gene and a transgene, (b) transforming the organism with said DNA construct such that the expression cassette is inserted into the genome, and (c) initiating post transcriptional gene silencing (PTGS) of said transgene in said organism, whereby initiation of PTGS of the transgene causes silencing of the target gene in the organism. The methods are based on a phenomenon termed “spreading” whereby PTGS of the transgene can be used to spread in trans to silence, for example, endogenous target genes in the same genetic background as the chimeric gene to give consistent, maintained, silencing thereof. Also provided are related materials (e.g. recombinant constructs) and uses and methods based on these.