Abstract: The disclosure relates to a work machine, comprising a primary energy source for feeding electric energy into a link, a gear for performing a task of the work machine, at least one electric drive connected to the link in order to operate the gear of the work machine, a holding brake for fixing or releasing the gear, and an energy store which is connected to the link in order to provide electric energy demanded from the link upon actuation of a gear and/or to absorb electric energy fed into the link. According to the disclosure, during an emergency lowering of the gear, the at least one electric drive to convert the kinetic energy into electric energy and to feed it into the link. In the event of an unavailability or failure, the primary energy source is configured to absorb the energy fed into the link by the electric drive.

Abstract: The disclosure relates to a work machine, comprising a primary energy source for feeding electric energy into a link, a gear for performing a task of the work machine, at least one electric drive connected to the link in order to operate the gear of the work machine, a holding brake for fixing or releasing the gear, and an energy store which is connected to the link in order to provide electric energy demanded from the link upon actuation of a gear and/or to absorb electric energy fed into the link. According to the disclosure, during an emergency lowering of the gear, the at least one electric drive to convert the kinetic energy into electric energy and to feed it into the link. In the event of an unavailability or failure, the primary energy source is configured to absorb the energy fed into the link by the electric drive.

Abstract: A method of preparing a pharmaceutical product comprises the steps of (a) providing a neat active pharmaceutical ingredient (API) complying with at least five of the following parameters determined by using a FT4 powder rheometer: (i) specific basic flow energy of at most 60 mJ/g; (ii) stability index of 0.75 to 1.25; (iii) specific energy of at most 10 mJ/g; (iv) major principle stress at 15 kPa of at most 40; (v) flow function at 15 kPa of at least 1.3; (vi) consolidated bulk density at 15 kPa of at least 0.26 g/mL; (vii) compressibility of at most 47%; and (viii) wall friction angle of at most 40°; (b) dispensing the neat API of step (a) into a bottom part of a pharmaceutical carrier using a vacuum assisted metering and filling device; and (c) encapsulating the bottom part, thereby producing a pharmaceutical product.

Abstract: A device for emergency supply of a high voltage onboard network, in particular for the emergency load lowering of a work machine such as a crane or a cable excavator, comprising a high voltage onboard network having an electrical drive unit and a primary DC energy source for supplying the electrical drive unit with energy; a low voltage onboard network, preferably a 12 V, 24 V, or 48 V onboard network, having a low voltage rechargeable battery for taking up and outputting energy, wherein the high voltage onboard network and the low voltage onboard network are connected via a DC/DC converter to allow an energy flow from the high voltage onboard network in the direction of the low voltage onboard network. The DC/DC converter is preferably a bidirectional DC/DC converter to permit an energy flow from the low voltage onboard network in the direction of the high voltage onboard network.

Abstract: The present invention relates to methods of preparing pharmaceutical products, involving filling active pharmaceutical ingredient powders into pharmaceutical carriers with a vacuum assisted metering and filling device. The methods disclosed herein can be used in a continuous process, such as in a high-throughput process for producing a pharmaceutical product. The present invention further relates to a particular quality of the neat active pharmaceutical ingredient (API) HDM201, i.e. siremadlin, present as succinic acid co-crystal, which can be used in the methods of preparation of the present invention.

Abstract: A device for emergency supply of a high voltage onboard network, in particular for the emergency load lowering of a work machine such as a crane or a cable excavator, comprising a high voltage onboard network having an electrical drive unit and a primary DC energy source for supplying the electrical drive unit with energy; a low voltage onboard network, preferably a 12 V, 24 V, or 48 V onboard network, having a low voltage rechargeable battery for taking up and outputting energy, wherein the high voltage onboard network and the low voltage onboard network are connected via a DC/DC converter to allow an energy flow from the high voltage onboard network in the direction of the low voltage onboard network. The DC/DC converter is preferably a bidirectional DC/DC converter to permit an energy flow from the low voltage onboard network in the direction of the high voltage onboard network.

Abstract: A method of preparing a pharmaceutical product comprises the steps of (a) providing a neat active pharmaceutical ingredient (API) complying with at least five of the following parameters determined by using a FT4 powder rheometer: (i) specific basic flow energy of at most 60 mJ/g; (ii) stability index of 0.75 to 1.25; (iii) specific energy of at most 10 mJ/g; (iv) major principle stress at 15 kPa of at most 40; (v) flow function at 15 kPa of at least 1.3; (vi) consolidated bulk density at 15 kPa of at least 0.26 g/mL; (vii) compressibility of at most 47%; and (viii) wall friction angle of at most 40°; (b) dispensing the neat API of step (a) into a bottom part of a pharmaceutical carrier using a vacuum assisted metering and filling device; and (c) encapsulating the bottom part, thereby producing a pharmaceutical product.

Abstract: A system, method, and apparatus for attenuating acoustic back-coupling in a ultrasonic meter transducer that includes a gasket band comprising a loop of a material, a first gasket ring integrated in the gasket band configured to match a diameter of a first bracket hole, and a second gasket ring integrated in the gasket band configured to match a diameter of a second bracket hole wherein the loop of material comprises a material that provides both environmental sealing and acoustic attenuation.

Abstract: A system, method, and apparatus for attenuating acoustic back-coupling in a ultrasonic meter transducer that includes a gasket band comprising a loop of a material, a first gasket ring integrated in the gasket band configured to match a diameter of a first bracket hole, and a second gasket ring integrated in the gasket band configured to match a diameter of a second bracket hole wherein the loop of material comprises a material that provides both environmental sealing and acoustic attenuation.

Abstract: A method for repair and preventive maintenance of railroad ties by application of a polymer system to the surface of the rail seat. The polymer system is cured by irradiation with ultraviolet light to fully cure or partially cure the polymer. The polymer system may be used in conjunction with a tie pad that is capable of transmitting ultraviolet light to permit curing of the polymer.

Abstract: A method for repair and preventive maintenance of railroad ties by application of a polymer system to the surface of the rail seat. The polymer system is cured by irradiation with ultraviolet light to fully cure or partially cure the polymer. The polymer system may be used in conjunction with a tie pad that is capable of transmitting ultraviolet light to permit curing of the polymer.

Abstract: A tie plate handling device for use in connection with removing and replacing railroad tie plates from a track during a rail change-out process. The tie plate handling device provides operator lift assistance and certain embodiments provide for a fully automated lift and movement of railroad tie plates. The tie plate handling device comprises a lifting arm, an engaging unit for securely coupling with a tie plate and a control unit for operating the same. Methods for using the tie plate handling device in conjunction with the rail change-out process are also described.

Abstract: A method for repair and preventive maintenance of railroad ties by application of a polymer system to the surface of the rail seat. The polymer system is cured by irradiation with ultraviolet light to fully cure or partially cure the polymer. The polymer system may be used in conjunction with a tie pad that is capable of transmitting ultraviolet light to permit curing of the polymer.

Abstract: A remedial railroad tie repair treatment capable of extending the useful life of a railroad tie. The remedial repair treatment comprises a mixture of a borate solution and a chemical tie plugging compound combined that, when applied to a wooden area of interest, will delay the decay thereof and facilitate penetration of the borate through the wood fibers. The remedial repair treatment may alternatively comprise sequential application of the borate solution and the plugging compound to the wooden area of interest.

Abstract: A method for repair and preventive maintenance of railroad ties by application of a polymer system to the surface of the rail seat. The polymer system is cured by irradiation with ultraviolet light to fully cure or partially cure the polymer. The polymer system may be used in conjunction with a tie pad that is capable of transmitting ultraviolet light to permit curing of the polymer.

Abstract: A remedial railroad tie repair treatment capable of extending the useful life of a railroad tie. The remedial repair treatment comprises a mixture of a borate solution and a chemical tie plugging compound combined that, when applied to a wooden area of interest, will delay the decay thereof and facilitate penetration of the borate through the wood fibers. The remedial repair treatment may alternatively comprise sequential application of the borate solution and the plugging compound to the wooden area of interest.