Patents by Inventor Fabien Lombardi

Fabien Lombardi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11207176
    Abstract: Some embodiments of the present disclosure provide a stent-valve for transcatheter implantation to replace a cardiac valve. In some embodiments, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation. In some embodiments, the stent-valve comprises a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprising material that swells in response to contact with blood or components thereof.
    Type: Grant
    Filed: November 4, 2016
    Date of Patent: December 28, 2021
    Assignee: BOSTON SCIENTIFIC SCIMED, INC.
    Inventors: Stephane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi
  • Publication number: 20210322159
    Abstract: Some embodiments of the present disclosure provide a stent-valve for transcatheter implantation to replace a cardiac valve. In some embodiments, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation. In some embodiments, the stent-valve comprises a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprising material that swells in response to contact with blood or components thereof.
    Type: Application
    Filed: May 18, 2021
    Publication date: October 21, 2021
    Applicant: BOSTON SCIENTIFIC LIMITED
    Inventors: Stephane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi
  • Publication number: 20210068949
    Abstract: A device for heart valve replacement comprises a valve component having at least two valve leaflets preferably made of pericardium tissue. Each valve leaflet includes at least two tabs. The device further includes a stent component configured to be radially compressible into a compressed state and expandable into a functional state. The stent component comprises a first end, a second end and at least one intermediate section arranged between said first and said second end. The intermediate section has at least two commissural posts generally aligned parallel to an axis spanning from the first end to the second end. The commissural posts are formed in the shape of a wishbone.
    Type: Application
    Filed: November 17, 2020
    Publication date: March 11, 2021
    Applicant: Symetis SA
    Inventors: Youssef Biadillah, Stephane Delaloye, Fabien Lombardi, Jean-Luc Hefti
  • Patent number: 10898321
    Abstract: A stent-valve for transcatheter implantation to replace a cardiac valve, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation, the stent-valve comprising a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprises material that swells in response to contact with blood. In some embodiments, the seal comprises a flap or pocket that is distensible in response to backpressure and/or paravalve back-flow of blood.
    Type: Grant
    Filed: March 7, 2019
    Date of Patent: January 26, 2021
    Assignee: Symetis SA
    Inventors: Stephane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi
  • Patent number: 10869760
    Abstract: A device for heart valve replacement comprises a valve component having at least two valve leaflets preferably made of pericardium tissue. Each valve leaflet includes at least two tabs. The device further includes a stent component configured to be radially compressible into a compressed state and expandable into a functional state. The stent component comprises a first end, a second end and at least one intermediate section arranged between said first and said second end. The intermediate section has at least two commissural posts generally aligned parallel to an axis spanning from the first end to the second end. The commissural posts are formed in the shape of a wishbone.
    Type: Grant
    Filed: February 11, 2019
    Date of Patent: December 22, 2020
    Assignee: Symetis SA
    Inventors: Youssef Biadillah, Stephane Delaloye, Fabien Lombardi, Jean-Luc Hefti
  • Publication number: 20200390550
    Abstract: A delivery catheter for a stent. The delivery catheter may comprise a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further comprises a handle at its proximal end and at least one sheath which may at least partially circumferentially cover said stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on said handle portion. The catheter further comprises at least one radio-opaque indicator for indicating a rotational orientation of the delivery catheter and/or the stent when observed using medical imaging during implantation of the stent.
    Type: Application
    Filed: June 16, 2020
    Publication date: December 17, 2020
    Inventors: Stephane Delaloye, Jean-Luc Hefti, Fabien Lombardi, Pierre Simonin
  • Patent number: 10709559
    Abstract: A delivery catheter for a stent. The delivery catheter may have a distal end and a proximal end. The distal end includes a stent attachment region adapted to receive a stent. The stent may be of the self-expanding type. The catheter further includes a handle at its proximal end and at least one sheath which may at least partially circumferentially cover the stent such as to retain it in a collapsed configuration. The sheath is coupled at its proximal end to an actuator located on the handle portion. The catheter further includes at least one radio-opaque indicator for indicating a rotational orientation of the delivery catheter and/or the stent when observed using medical imaging during implantation of the stent.
    Type: Grant
    Filed: October 13, 2015
    Date of Patent: July 14, 2020
    Assignee: BOSTON SCIENTIFIC LIMITED
    Inventors: Stephane Delaloye, Jean-Luc Hefti, Fabien Lombardi, Pierre Simonin
  • Publication number: 20200205971
    Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a first compressor stage (100) including a hollow channel (42) with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage (102) comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.
    Type: Application
    Filed: February 26, 2020
    Publication date: July 2, 2020
    Applicant: Symetis SA
    Inventors: Luc Mantanus, Fabien Lombardi, Pierre Simonin, Youssef Biadillah, Jean-Luc Hefti, Stephane Delaloye
  • Patent number: 10682228
    Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a first compressor stage (100) including a hollow channel (42) with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage (102) comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.
    Type: Grant
    Filed: April 1, 2019
    Date of Patent: June 16, 2020
    Assignee: Symetis SA
    Inventors: Luc Mantanus, Fabien Lombardi, Pierre Simonin, Youssef Biadillah, Jean-Luc Hefti, Stephane Delaloye
  • Publication number: 20200069422
    Abstract: Embodiments of the present disclosure are directed to stents, valved-stents, and associated methods and systems for their delivery via minimally-invasive surgery.
    Type: Application
    Filed: July 2, 2019
    Publication date: March 5, 2020
    Applicant: Symetis SA
    Inventors: JACQUES ESSINGER, STEPHANE DELALOYE, JEAN-LUC HEFTI, YOUSSEF BIADILLAH, LUC MANTANUS, IKER MALLABIABARRENA, REYNALD PASSERINI, MICHAEL PARIS, FABIEN LOMBARDI
  • Patent number: 10531953
    Abstract: A delivery apparatus for delivering a stent-valve for implantation within the body, the delivery apparatus configured for introduction into the body through an arterial introducer of a type having a stem insertable into the body and a mouth section that remains outside the body, the mouth section including a haemostasis valve, and wherein the delivery apparatus comprises: a first constraining sheath at a stent-valve accommodation region of the apparatus at a distal end of the apparatus, and configured for constraining at least a portion of a stent-valve at the accommodation region in a radially collapsed configuration; a delivery introducer captive on the delivery apparatus, and slidable between a first position surrounding at least a portion of the stent-valve accommodation region, and a second position in which the delivery introducer slides proximally of the stent-valve accommodation region; wherein the delivery introducer is insertable at least partly into the mouth of a said arterial introducer, the deli
    Type: Grant
    Filed: October 28, 2014
    Date of Patent: January 14, 2020
    Assignee: SYMETIS SA
    Inventors: Fabien Lombardi, Jacques Essinger, Stéphane Delaloye, Jean-Luc Hefti, Luc Mantanus, Youssef Biadillah, Pierre Simonin
  • Publication number: 20190314151
    Abstract: A device for heart valve replacement comprises a valve component having at least two valve leaflets preferably made of pericardium tissue. Each valve leaflet includes at least two tabs. The device further includes a stent component configured to be radially compressible into a compressed state and expandable into a functional state. The stent component comprises a first end, a second end and at least one intermediate section arranged between said first and said second end. The intermediate section has at least two commissural posts generally aligned parallel to an axis spanning from the first end to the second end. The commissural posts are formed in the shape of a wishbone.
    Type: Application
    Filed: February 11, 2019
    Publication date: October 17, 2019
    Applicant: Symetis SA
    Inventors: Youssef Biadillah, Stephane Delaloye, Fabien Lombardi, Jean-Luc Hefti
  • Publication number: 20190290427
    Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a first compressor stage (100) including a hollow channel (42) with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage (102) comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.
    Type: Application
    Filed: April 1, 2019
    Publication date: September 26, 2019
    Applicant: Symetis SA
    Inventors: Luc Mantanus, Fabien Lombardi, Pierre Simonin, Youssef Biadillah, Jean-Luc Hefti, Stephane Delaloye
  • Patent number: 10420658
    Abstract: Embodiments of the present disclosure are related to devices and techniques for para-valve sealing of an expandable stent-valve implanted using a catheter. In some embodiments, a stent-valve is provided which comprises a seal sleeve/cuff containing material that swells when contacted by blood. A piercing tool may be included and used to permit a user to puncture the sleeve/cuff prior to introduction into a patient's body. In some embodiments, the sleeve/cuff has an integral tubular structure configured to withstand balloon expansion of the stent-valve during or after implantation. In some embodiments, the seal is provided as a separate component from the stent-valve.
    Type: Grant
    Filed: March 13, 2014
    Date of Patent: September 24, 2019
    Assignee: SYMETIS SA
    Inventors: Stéphane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi, Lionel Flaction, Yutit Wanakoht
  • Publication number: 20190231523
    Abstract: A delivery catheter for a prosthetic heart valve, the valve expandable from a collapsed condition for delivery to an expanded condition for implantation, the delivery catheter comprising: a holder for engaging the valve in the collapsed state of the valve, the holder configured such that (i) in response to a radial compression force exerted thereon, the holder has a first shape defining an exposed engagement region for engaging at least a portion of the collapsed prosthetic heart valve for restraining axial displacement of the prosthetic valve in at least one axial direction of the catheter, and (ii) in response to removal of the radial compression force upon expansion of the valve, at least a portion of the holder transitions to a second shape
    Type: Application
    Filed: April 13, 2019
    Publication date: August 1, 2019
    Applicant: Symetis SA
    Inventors: Fabien Lombardi, Youssef Biadillah, Jean-Luc Hefti, Luc Mantanus, Stephane Delaoye
  • Publication number: 20190201193
    Abstract: A stent-valve for transcatheter implantation to replace a cardiac valve, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation, the stent-valve comprising a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprises material that swells in response to contact with blood. In some embodiments, the seal comprises a flap or pocket that is distensible in response to backpressure and/or paravalve back-flow of blood.
    Type: Application
    Filed: March 7, 2019
    Publication date: July 4, 2019
    Applicant: Symetis SA
    Inventors: Stephane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi
  • Patent number: 10285811
    Abstract: A delivery catheter for a prosthetic heart valve, the valve expandable from a collapsed condition for delivery to an ex paneled condition for implantation, the delivery catheter comprising: a holder for engaging the valve in the collapsed state of the valve, the holder configured such that (i) in response to a radial compression force exerted thereon, the holder has a first shape defining an exposed engagement region for engaging at least a portion of the collapsed prosthetic heart valve for restraining axial displacement of the prosthetic valve in at least one axial direction of the catheter, and (ii) in response to removal of the radial compression force upon expansion of the valve, at least a portion of the holder transitions to a second shape.
    Type: Grant
    Filed: February 6, 2014
    Date of Patent: May 14, 2019
    Assignee: SYMETIS, SA
    Inventors: Fabien Lombardi, Youssef Biadillah, Jean-Luc Hefti, Luc Mantanus, Stéphane Delaloye
  • Patent number: 10258464
    Abstract: A stent-valve for transcatheter implantation to replace a cardiac valve, the stent valve being compressible to a compressed state for delivery, and expandable to an operative state for implantation, the stent-valve comprising a stent, a plurality of leaflets for defining a prosthetic valve, an inner skirt, an outer skirt, and a paravalve seal for sealing against surrounding tissue. In some embodiments, the paravalve seal comprises material that swells in response to contact with blood. In some embodiments, the seal comprises a flap or pocket that is distensible in response to backpressure and/or paravalve back-flow of blood.
    Type: Grant
    Filed: March 25, 2013
    Date of Patent: April 16, 2019
    Assignee: SYMETIS SA
    Inventors: Stéphane Delaloye, Jacques Essinger, Jean-Luc Hefti, Youssef Biadillah, Luc Mantanus, Fabien Lombardi
  • Patent number: 10245145
    Abstract: Apparatus (40) for compressing a transcatheter cardiac stent-valve (10) comprises: a first compressor stage (100) including a hollow channel (42) with a tapered interior surface configured for compressing a stent-valve in response to longitudinal advancement of the stent-valve within the channel; and a second compressor stage (102) comprising a crimper for compressing a portion of the stent-valve without longitudinal advancement.
    Type: Grant
    Filed: September 16, 2014
    Date of Patent: April 2, 2019
    Assignee: SYMETIS SA
    Inventors: Luc Mantanus, Fabien Lombardi, Pierre Simonin, Youssef Biadillah, Jean-Luc Hefti, Stéphane Delaloye
  • Patent number: 10201418
    Abstract: A device for heart valve replacement comprises a valve component having at least two valve leaflets preferably made of pericardium tissue. Each valve leaflet includes at least two tabs. The device further includes a stent component configured to be radially compressible into a compressed state and expandable into a functional state. The stent component comprises a first end, a second end and at least one intermediate section arranged between said first and said second end. The intermediate section has at least two commissural posts generally aligned parallel to an axis spanning from the first end to the second end. The commissural posts are formed in the shape of a wishbone.
    Type: Grant
    Filed: April 29, 2016
    Date of Patent: February 12, 2019
    Assignee: SYMETIS, SA
    Inventors: Youssef Biadillah, Stephane Delaloye, Fabien Lombardi, Jean-Luc Hefti