Patents by Inventor Fabienne Dudouit

Fabienne Dudouit has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combi-molecules having signal transduction inhibitory properties and DNA damaging properties
    Patent number: 7572798
    Abstract: The present invention relates to a series of new chemical agents that demonstrate anti-tumor activity. More particularly, the present invention relates to molecules, referred to as “combi-molecules”, that combine two major mechanisms of anti-tumor action. A combi-molecule is capable of degrading to a ligand involved in cell signaling pathways and to an agent capable of damaging DNA. More specifically, the present invention relates to molecules capable of blocking epidermal growth factor receptor (EGFR) mediated signal transduction and capable of damaging DNA. The present invention also relates to a general method of synthesis of these combi-molecules.
    Type: Grant
    Filed: February 26, 2002
    Date of Patent: August 11, 2009
    Assignee: McGill University
    Inventors: Bertrand J. Jean-Claude, Fabienne Dudouit, Stephanie Matheson
  • Combi-molecules having signal transduction inhibitory properties and dna damaging properties
    Publication number: 20040086907
    Abstract: The present invention relates to a series of new chemical agents that demonstrate anti-tumor activity. More particularly, the present invention relates to molecules, referred to as “combi-molecules”, that combine two major mechanisms of anti-tumor action. A combi-molecule is capable of degrading to a ligand involved in cell signaling pathways and to an agent capable of damaging DNA. More specifically, the present invention relates to molecules capable of blocking epidermal growth factor receptor (EGFR) mediated signal transduction and capable of damaging DNA. The present invention also relates to a general method of synthesis of these combi-molecules.
    Type: Application
    Filed: December 31, 2003
    Publication date: May 6, 2004
    Inventors: Bertrand J. Jean-Claude, Fabienne Dudouit, Stephanie Matheson