Patents by Inventor Fabienne Grellepois

Fabienne Grellepois has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Dimeric derivatives of artemisinin and application in anticancer therapy
    Patent number: 8236850
    Abstract: The present invention relates to dimeric derivatives of 10-trifluoromethylated artemisinin of formula (I): or a pharmaceutically acceptable salt thereof with B1 and B2 selected from C?O, CHOH and CH2, as well as to their use in treating cancer and to their preparation method.
    Type: Grant
    Filed: December 22, 2008
    Date of Patent: August 7, 2012
    Assignees: Pierre Fabre Medicament, Centre National de la Recherche Scientifique, Universite Paris-Sud 11
    Inventors: Jean-Pierre Begue, Danielle Bonnet-Delpon, Benoît Crousse, Fabienne Grellepois, Constance Chollet, Jacques Fahy, Céline Mordant
  • DIMERIC DERIVATIVES OF ARTEMISININ AND APPLICATION IN ANTICANCER THERAPY
    Publication number: 20100266570
    Abstract: The present invention relates to dimeric derivatives of 10-trifluoromethylated artemisinin of formula (I): or a pharmaceutically acceptable salt thereof with B1 and B2 selected from C?O, CHOH and CH2, as well as to their use in treating cancer and to their preparation method.
    Type: Application
    Filed: December 22, 2008
    Publication date: October 21, 2010
    Applicants: Pierre Fabre Medicament, Centre National De La Recherche Scientifique, Universite Paris-Sud 11
    Inventors: Jean-Pierre Begue, Danièle Bonnet-Delpon, Benoît Crousse, Fabienne Grellepois, Constance Chollet, Jacques Fahy, Céline Mordant
  • Derivatives of artemisinin, and their uses in the treatment of malaria
    Patent number: 7696362
    Abstract: A new artemisinin derivatives, of following general formula (I): In which: a and b are a single or a double bond, n1 and n2 are 0 or 1, R1 is a fluoroalkyl group or a fluoroaryl group, R2 is a hydrogen atom, or a halogen atom, or a group, if appropriate ionisable, making it possible to render said compounds of formula (I) water-soluble, R3 is a group, if appropriate ionisable, making it possible to render said compounds of formula (I) water-soluble, R4 is H or OH. The invention also relates to the process by which they are obtained, and their uses in pharmaceutical compositions intended for the treatment of malaria.
    Type: Grant
    Filed: July 9, 2008
    Date of Patent: April 13, 2010
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Jean-Pierre Begue, Danièle Bonnet-Delpon, Benoît Crousse, Michèle Ourevitch, Fatima Chorki, Fabienne Grellepois, Guillaume Magueur
  • DERIVATIVES OF ARTEMISININ, AND THEIR USES IN THE TREATMENT OF MALARIA
    Publication number: 20080287433
    Abstract: A new artemisinin derivatives, of following general formula (I): In which: a and b are a single or a double bond, n1 and n2 are 0 or 1, R1 is a fluoroalkyl group or a fluoroaryl group, R2 is a hydrogen atom, or a halogen atom, or a group, if appropriate ionisable, making it possible to render said compounds of formula (I) water-soluble, R3 is a group, if appropriate ionisable, making it possible to render said compounds of formula (I) water-soluble, R4 is H or OH. The invention also relates to the process by which they are obtained, and their uses in pharmaceutical compositions intended for the treatment of malaria.
    Type: Application
    Filed: July 9, 2008
    Publication date: November 20, 2008
    Applicant: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Jean-Pierre Begue, Daniele Bonnet-Delpon, Benoit Crousse, Michele Ourevitch, Fatima Chorki, Fabienne Grellepois, Guillaume Magueur
  • Artemisinine derivatives, and uses thereof for treating malaria
    Patent number: 7417155
    Abstract: A new artemisinin derivatives, of following general formula (I): In which: a and b represent a single or a double bond, n1 and n2 represent 0 or 1, R1 represents a fluoroalkyl group or a fluoroaryl group, R2 represents a hydrogen atom, or a halogen atom, or a group, if appropriate ionisable, making it possible to render said compounds of formula (I) water-soluble, R3 represents a group, if appropriate ionisable, making it possible to render said compounds of formula (I) water-soluble, R4 represents H or OH. The invention also relates to the process by which they are obtained, and their uses in pharmaceutical compositions intended for the treatment of malaria.
    Type: Grant
    Filed: October 25, 2002
    Date of Patent: August 26, 2008
    Assignee: Centre National de la Recherche Scientifique
    Inventors: Jean-Pierre Begue, Danièle Bonnet-Delpon, Benoît Crousse, Michèle Ourevitch, Fatima Chorki, Fabienne Grellepois, Guillaume Magueur
  • Novel artemisinine derivatives, and uses thereof for treating malaria
    Publication number: 20050038024
    Abstract: A new artemisinin derivatives, of following general formula (I): In which: a and b represent a single or a double bond, n1 and n2 represent 0 or 1, R1 represents a fluoroalkyl group or a fluoroaryl group, R2 represents a hydrogen atom, or a halogen atom, or a group, if appropriate ionisable, making it possible to render said compounds of formula (I) water-soluble, R3 represents a group, if appropriate ionisable, making it possible to render said compounds of formula (I) water-soluble, R4 represents H or OH. The invention also relates to the process by which they are obtained, and their uses in pharmaceutical compositions intended for the treatment of malaria.
    Type: Application
    Filed: October 25, 2002
    Publication date: February 17, 2005
    Inventors: Jean-Pierre Begue, Daniele Bonnet-Delpon, Benoit Crousse, Michele Ourevitch, Fatima Chorki, Fabienne Grellepois, Guillaume Magueur