Patents by Inventor Fabienne MacKay

Fabienne MacKay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF MODULATING IMMUNE RESPONSES USING BCMA POLYPEPTIDE
    Publication number: 20200095305
    Abstract: A novel receptor in the TNF family is provided: BAFF-R. Chimeric molecules and antibodies to BAFF-R and methods of use thereof are also provided.
    Type: Application
    Filed: October 16, 2019
    Publication date: March 26, 2020
    Applicants: Biogen MA Inc., Topotarget Switzerland SA
    Inventors: Jeffrey Browning, Christine Ambrose, Fabienne MacKay, Jurg Tschopp, Pascal Schneider, Jeffrey Thompson
  • Methods of modulating immune responses using BCMA polypeptide
    Patent number: 10494416
    Abstract: A novel receptor in the TNF family is provided: BAFF-R. Chimeric molecules and antibodies to BAFF-R and methods of use thereof are also provided.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: December 3, 2019
    Assignees: Biogen MA Inc., Topotarget Switzerland SA
    Inventors: Jeffrey Browning, Christine Ambrose, Fabienne MacKay, Jurg Tschopp, Pascal Schneider, Jeffrey Thompson
  • METHODS OF MODULATING IMMUNE RESPONSES USING BCMA POLYPEPTIDE
    Publication number: 20180273605
    Abstract: A novel receptor in the TNF family is provided: BAFF-R. Chimeric molecules and antibodies to BAFF-R and methods of use thereof are also provided.
    Type: Application
    Filed: May 15, 2017
    Publication date: September 27, 2018
    Applicants: Biogen MA Inc., Topotarget Switzerland SA
    Inventors: Jeffrey Browning, Christine Ambrose, Fabienne MacKay, Jurg Tschopp, Pascal Schneider, Jeffrey Thompson
  • Methods of treating autoimmune diseases using a B-cell maturation antigen (BCMA)
    Patent number: 9650430
    Abstract: A novel receptor in the TNF family is provided: BAFF-R. Chimeric molecules and antibodies to BAFF-R and methods of use thereof are also provided.
    Type: Grant
    Filed: August 6, 2014
    Date of Patent: May 16, 2017
    Assignee: BIOGEN, MA INC.
    Inventors: Jeffrey Browning, Christine Ambrose, Fabienne MacKay, Jurg Tschopp, Pascal Schneider, Jeffrey Thompson
  • BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders
    Patent number: 9545086
    Abstract: The invention provides methods for treating or preventing disorders associated with expression of BAFF comprising BAFF and fragments thereof, antibodies, agonists and antagonists.
    Type: Grant
    Filed: April 2, 2008
    Date of Patent: January 17, 2017
    Assignee: Biogen MA Inc.
    Inventors: Fabienne MacKay, Susan Kalled
  • BAFF RECEPTOR (BCMA), AN IMMUNOREGULATORY AGENT
    Publication number: 20150139992
    Abstract: A novel receptor in the TNF family is provided: BAFF-R. Chimeric molecules and antibodies to BAFF-R and methods of use thereof are also provided.
    Type: Application
    Filed: August 6, 2014
    Publication date: May 21, 2015
    Applicants: TOPOTARGET SWITZERLAND SA, BIOGEN IDEC MA INC.
    Inventors: Jeffrey Browning, Christine Ambrose, Fabienne MacKay, Jurg Tschopp, Pascal Schneider, Jeffrey Thompson
  • Methods of screening for a compound that inhibits the interaction between BAFF and BCMA
    Patent number: 8828669
    Abstract: A novel receptor in the TNF family is provided: BAFF-R. Chimeric molecules and antibodies to BAFF-R and methods of use thereof are also provided.
    Type: Grant
    Filed: February 21, 2012
    Date of Patent: September 9, 2014
    Assignee: Biogen Idec MA Inc.
    Inventors: Jeffrey Browning, Christine Ambrose, Fabienne MacKay, Jurg Tschopp, Pascal Schneider, Jeffrey Thompson
  • Soluble lymphotoxin-beta receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological diseases
    Patent number: 8287874
    Abstract: Compositions and methods comprising “lymphotoxin-? receptor blocking agents” which block lymphotoxin-? receptor signalling and are useful for altering immunological diseases, and particularly antibody mediated immune responses.
    Type: Grant
    Filed: June 10, 2010
    Date of Patent: October 16, 2012
    Assignee: Biogen Idec MA Inc.
    Inventors: Jeffrey L. Browning, Paula S. Hochman, Paul D. Rennert, Fabienne Mackay
  • SOLUBLE LYMPHOTOXIN-BETA RECEPTORS AND ANTI-LYMPHOTOXIN RECEPTOR AND LIGAND ANTIBODIES AS THERAPEUTIC AGENTS FOR THE TREATMENT OF IMMUNOLOGICAL DISEASES
    Publication number: 20120156214
    Abstract: Compositions and methods comprising “lymphotoxin-? receptor blocking agents” which block lymphotoxin-? receptor signalling and are useful for altering immunological diseases, and particularly antibody mediated immune responses.
    Type: Application
    Filed: June 10, 2010
    Publication date: June 21, 2012
    Applicant: BIOGEN IDEC MA INC.
    Inventors: Jeffrey L. BROWNING, Paula S. HOCHMAN, Paul D. RENNERT, Fabienne MACKAY
  • BAFF, inhibitors thereof and their use in the modulation of B-cell response
    Publication number: 20100233179
    Abstract: The invention provides methods for treating or preventing disorders associated with expression of BAFF comprising BAFF and fragments thereof, antibodies, agonists and antagonists.
    Type: Application
    Filed: September 30, 2009
    Publication date: September 16, 2010
    Inventors: Jeffrey Browning, Christine Ambrose, Fabienne MacKay, Jurg Tschopp, Pascal Schneider
  • Soluble lymphotoxin-beta receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological diseases
    Patent number: 7744891
    Abstract: Compositions and methods comprising “lymphotoxin-? receptor blocking agents” which block lymphotoxin-? receptor signaling and are useful for altering immunological diseases, and particularly antibody mediated immune responses.
    Type: Grant
    Filed: August 13, 2007
    Date of Patent: June 29, 2010
    Assignee: Biogen Idec MA Inc.
    Inventors: Jeffrey L. Browning, Paula S. Hochman, Paul D. Rennert, Fabienne Mackay
  • BAFF, Inhibitors Thereof and Their Use in the Modulation of B-Cell Response and Treatment of Autoimmune Disorders
    Publication number: 20090110676
    Abstract: The invention provides methods for treating or preventing disorders associated with expression of BAFF comprising BAFF and fragments thereof, antibodies, agonists and antagonists.
    Type: Application
    Filed: April 2, 2008
    Publication date: April 30, 2009
    Inventors: FABIENNE MACKAY, SUSAN KALLED
  • Use of Baff to Treat Th2-Mediated Conditions
    Publication number: 20080254030
    Abstract: Compositions and methods for treating Th2-mediated disease are provided.
    Type: Application
    Filed: January 27, 2006
    Publication date: October 16, 2008
    Inventors: Charles Mackay, Fabienne Mackay, Susan Kalled
  • Soluble lymphotoxin-beta receptors and anti-lymphotoxin receptor and ligand antibodies as therapeutic agents for the treatment of immunological diseases
    Publication number: 20080219967
    Abstract: Compositions and methods comprising “lymphotoxin-? receptor blocking agents” which block lymphotoxin-? receptor signaling and are useful for altering immunological diseases, and particularly antibody mediated immune responses.
    Type: Application
    Filed: August 13, 2007
    Publication date: September 11, 2008
    Applicant: Biogen Idec MA Inc.
    Inventors: Jeffrey L. Browning, Paula S. Hochman, Paul D. Rennert, Fabienne MacKay
  • Soluble lymphotoxin-? receptors as therapeutic agents for the treatment of systemic lupus erythematosus
    Patent number: 7309492
    Abstract: Compositions and methods comprising “lymphotoxin-? receptor blocking agents” which block lymphotoxin-? receptor signaling and are useful for altering immunological diseases, and particularly antibody mediated immune responses.
    Type: Grant
    Filed: October 31, 2001
    Date of Patent: December 18, 2007
    Assignee: Biogen Idec MA Inc.
    Inventors: Jeffrey L. Browning, Paula S. Hochman, Paul D. Rennert, Fabienne MacKay
  • Use of lymphotoxin-? receptor blocking agents for the treatment of antibody mediated immunological diseases
    Patent number: 7255854
    Abstract: Compositions and methods comprising “lymphotoxin-? receptor blocking agents” which block lymphotoxin-? receptor signaling and are useful for altering immunological diseases, and particularly antibody mediated immune responses.
    Type: Grant
    Filed: April 23, 1999
    Date of Patent: August 14, 2007
    Assignee: Biogen, Inc.
    Inventors: Jeffrey L. Browning, Paula S. Hochman, Paul D. Rennert, Fabienne Mackay
  • Methods of treatment by administering an anti-BCMA antibody
    Patent number: 7083785
    Abstract: A novel receptor in the TNF family is provided: BAFF-R. Chimeric molecules and antibodies to BAFF-R and methods of use thereof are also provided.
    Type: Grant
    Filed: February 15, 2002
    Date of Patent: August 1, 2006
    Assignees: Biogen Idcc MA Inc., Apoxis SA
    Inventors: Jeffrey Browning, Christine Ambrose, Fabienne MacKay, Jurg Tschopp, Pascal Schneider, Jeffrey Thompson
  • BAFF, inhibitors thereof and their use in the modulation of B-cell response
    Publication number: 20060079457
    Abstract: The invention provides methods for treating or preventing disorders associated with expression of BAFF comprising BAFF and fragments thereof, antibodies, agonists and antagonists.
    Type: Application
    Filed: October 14, 2005
    Publication date: April 13, 2006
    Inventors: Jeffrey Browning, Christine Ambrose, Fabienne MacKay, Jurg Tschopp, Pascal Schneider
  • BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders
    Publication number: 20050244411
    Abstract: The invention provides methods for treating or preventing disorders associated with expression of BAFF comprising BAFF and fragments thereof, antibodies, agonists and antagonists.
    Type: Application
    Filed: February 24, 2005
    Publication date: November 3, 2005
    Inventors: Fabienne MacKay, Susan Kalled
  • BAFF, inhibitors thereof and their use in the modulation of B-cell response
    Publication number: 20050169924
    Abstract: The invention provides methods for treating or preventing disorders associated with expression of BAFF comprising BAFF and fragments thereof, antibodies, agonists and antagonists.
    Type: Application
    Filed: March 16, 2005
    Publication date: August 4, 2005
    Inventors: Jeffrey Browning, Christine Ambrose, Fabienne MacKay, Jurg Tschopp, Pascal Schneider