Patents by Inventor Fabio Carli

Fabio Carli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5510114
    Abstract: A slow-release pharmaceutical composition containing a bile acid as active ingredient and comprising at least one bioadhesive substance and at least one high specific gravity substance, an aliquot thereof being enteric coated and the remainder being non-enteric coated.
    Type: Grant
    Filed: May 2, 1994
    Date of Patent: April 23, 1996
    Assignee: Instituto Biochimico Italiano Giovanni Lorenzini S.p.A.
    Inventors: Fabio Borella, Alberto Brandt, Fabio Carli
  • Patent number: 5275824
    Abstract: The described therapeutic compositions with controlled release of medicaments comprise a medicament loaded onto particles of a crosslinked non-ionic polymer insoluble but swellable in water, using either swelling with solutions of the medicament or high-energy co-grinding methods. The medicament-loaded particles are coated with a polymers film able to control medicament release, to obtain a prolonged release of the medicament (even exceeding 24 hours) while maintaining high bioavailability.
    Type: Grant
    Filed: December 3, 1990
    Date of Patent: January 4, 1994
    Assignee: Vectorpharma International spa
    Inventors: Fabio Carli, Italo Colombo, Leonardo Rabaglia
  • Patent number: 5164380
    Abstract: A process for preparing complexes of piroxicam with cyclodextrins in which the two components in the powder state are premixed and then co-ground in a high energy mill in the presence of steam.The products obtained have technological, physical and biopharmacological characteristics which are advantageous compared with those of liquid-state complexes obtained by traditional methods, and are suitable for preparing pharmaceutical compositions for oral, rectal and topical use.
    Type: Grant
    Filed: March 27, 1991
    Date of Patent: November 17, 1992
    Assignee: Chiesi Farmaceutici S.p.A.
    Inventors: Fabio Carli, Paolo Chiesi
  • Patent number: 4639370
    Abstract: A water-swellable, water-insoluble polymer is loaded with a biologically active substance or substance convertible into a biologically active substance in vivo by preparing and grinding a mixture of a said substance with a water-swellable, water-insoluble polymer in a weight ratio of the said substance:polymer of from 1:0.1 to 1:100. The thus-loaded polymer is useful as a pharmaceutical composition.
    Type: Grant
    Filed: February 6, 1985
    Date of Patent: January 27, 1987
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventor: Fabio Carli
  • Patent number: 4632828
    Abstract: A water-swellable, water-insoluble polymer is loaded with methylhydroxyprogesterone acetate (MAP) by:(a) preparing and grinding a mixture of a said polymer and MAP; or(b)(i) preparing a mixture of a said polymer which is stable under the heating to which the mixture is subjected in step (ii) and MAP and (ii) heating the mixture up to the melting temperature of MAP; or(c) swelling a said polymer with a MAP solution capable thereof and drying the resulting swollen polymer/MAP system.The MAP loaded polymer is useful as a pharmaceutical composition.
    Type: Grant
    Filed: February 6, 1985
    Date of Patent: December 30, 1986
    Assignee: Farmitalia Carlo Erba S.p.A.
    Inventor: Fabio Carli