Patents by Inventor Fabio Donzelli

Fabio Donzelli has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SEMISYNTHETIC PROCESS FOR THE PREPARATION OF COLCHICINE
    Publication number: 20230227873
    Abstract: The invention relates to a process for the preparation of colchicine 1 from colchicoside 2 which comprises enzymatic conversion of colchicoside 2 to 3-O-demethylcolchicine 3, wherein the enzyme used is a cellulase. According to another aspect of the invention, 3-O-demethylcolchicine 3 can be converted to colchicine 1 using an alkylating agent. The invention also relates to a process or enriching the colchicine 1 content of extracts from plants belonging to the Colchicaceae family containing colchicine 1, colchicoside 2 and 3-(9-demethyl colchicine 3, which comprises conversion by means of a colchicoside 2 cellulase to 3-O-demethylcolchicine 3, followed by conversion of 3-O-demethylcolchicine 3 to colchicine 1 using an alkylating agent.
    Type: Application
    Filed: June 14, 2021
    Publication date: July 20, 2023
    Applicant: Indena S.P.A.
    Inventors: Fabio Donzelli, Pietro Allegrini, Alessandro Andreani, Andrea Gambini, Davide Berlanda
  • Phaseolus vulgaris extracts, their use and formulations containing them
    Patent number: 11241470
    Abstract: Extract obtainable by extraction from Phaseolus sp. with mixtures of ethanol and water, characterised by an ?-amylase inhibitor content in between 1,000 and 1,600 USP/mg (HPLC titre between 6 and 14% w/w) and a phytohaemagglutinin content in between 8,000 and 30,000 HAU/g, and a process for its preparation.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: February 8, 2022
    Assignee: INDENA S.P.A.
    Inventors: Davide Berlanda, Marco Bertani, Ezio Bombardelli, Andrea Gardi, Cesare Ponzone, Fabio Donzelli
  • PHASEOLUS VULGARIS EXTRACTS, THEIR USE AND FORMULATIONS CONTAINING THEM
    Publication number: 20170333508
    Abstract: Extract obtainable by extraction from Phaseolus sp. with mixtures of ethanol and water, characterised by an ?-amylase inhibitor content in between 1,000 and 1,600 USP/mg (HPLC titre between 6 and 14% w/w) and a phytohaemagglutinin content in between 8,000 and 30,000 HAU/g, and a process for its preparation.
    Type: Application
    Filed: July 7, 2017
    Publication date: November 23, 2017
    Inventors: DAVIDE BERLANDA, MARCO BERTANI, EZIO BOMBARDELLI, ANDREA GARDI, CESARE PONZONE, FABIO DONZELLI
  • PHASEOLUS VULGARIS EXTRACTS, THEIR USE, AND FORMULATIONS CONTAINING THEM
    Publication number: 20090169657
    Abstract: Extract obtainable by extraction from Phaseolus sp. with mixtures of ethanol and water, characterised by an ?-amylase inhibitor content in between 1,000 and 1,600 USP/mg (HPLC titre between 6 and 14% w/w) and a phytohaemagglutinin content in between 8,000 and 30,000 HAU/g, and a process for its preparation.
    Type: Application
    Filed: December 13, 2006
    Publication date: July 2, 2009
    Inventors: Davide Berlanda, Marco Bertani, Ezio Bombardelli, Fabio Donzelli, Andrea Gardi, Cesare Ponzone
  • PHASEOLUS VULGARIS EXTRACTS, THEIR USE, AND FORMULATIONS CONTAINING THEM
    Publication number: 20090093397
    Abstract: Extracts obtainable by extraction from Phaseolus sp. with aqueous solutions, characterised by an ?-amylase inhibitor content with an activity equal to or greater than 1,800 USP/mg (HPLC titre equal to or greater than 15% w/w) and a phytohaemagglutinin content of between 1,500 and 6,000 HAU/g, and a process for its preparation.
    Type: Application
    Filed: December 13, 2006
    Publication date: April 9, 2009
    Inventors: Davide Berlanda, Marco Bertani, Ezio Bombardelli, Fabio Donzelli, Andrea Gardi, Cesare Ponzone