Patents by Inventor Fabio Palumbo

Fabio Palumbo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9410000
    Abstract: In this invention a two steps procedure is described useful to insert functional groups to the hyaluronic acid (HA), through the formation, in organic solvent, of a particular active group on hydroxyl groups of HA and subsequent substitution, on the inserted active group, with a pendant portion containing at least in its terminal portion a nucleophilic functional group, NH2—R. The group inserted by nucleophilic substitution can contain in another its terminal portion a further nucleophilic functional group, in a way to be easily exploitable to further chemical functionalizations, such as an example to obtain the methacrylation of HA functional groups, to obtain photocrosslinkable derivatives. Both direct derivatives of the proposed process and those obtained by the further functionalization can be employed to produce hydrogels.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: August 9, 2016
    Assignee: UNIVERSITA' DEGLI STUDI DI PALERMO
    Inventors: Gaetano Giammona, Fabio Palumbo, Giovanna Pitarresi
  • Patent number: 9283283
    Abstract: The present invention relates to hydrogels based on hyaluronic acid based derivatives, that are more resistant than hyaluronic acid alone towards chemical and enzymatic degradation and are endowed with a mix of chemical and mechanical properties such that they are of optimal use in several surgeries, for instance for injection in bone fractures or cavities and for the production of coatings of prostheses in orthopedic surgery, as fillers in cosmetic and maxillo-facial surgery, as anti-adhesion barrier in the prevention of postoperative adhesions in abdominal and abdominal/pelvic surgery, and in general surgery. These hydrogels can be loaded with several different kinds of compounds having pharmacological and biological activity, that are then released from the hydrogel in the site of intervention.
    Type: Grant
    Filed: July 29, 2011
    Date of Patent: March 15, 2016
    Assignees: MERO S.R.L., NOVAGENIT S.R.L.
    Inventors: Gaetano Giammona, Giovanna Pitarresi, Fabio Palumbo, Carlo Luca Romano′, Enzo Meani, Edgardo Cremascoli
  • Publication number: 20150183891
    Abstract: In this invention a two steps procedure is described useful to insert functional groups to the hyaluronic acid (HA), through the formation, in organic solvent, of a particular active group on hydroxyl groups of HA and subsequent substitution, on the inserted active group, with a pendant portion containing at least in its terminal portion a nucleophilic functional group, NH2—R. The group inserted by nucleophilic substitution can contain in another its terminal portion a further nucleophilic functional group, in a way to be easily exploitable to further chemical functionalizations, such as an example to obtain the methacrylation of HA functional groups, to obtain photocrosslinkable derivatives. Both direct derivatives of the proposed process and those obtained by the further functionalization can be employed to produce hydrogels.
    Type: Application
    Filed: November 13, 2014
    Publication date: July 2, 2015
    Applicant: UNIVERSITA' DEGLI STUDI DI PALERMO
    Inventors: Gaetano GIAMMONA, Fabio PALUMBO, Giovanna PITARRESI
  • Patent number: 8858999
    Abstract: In this invention a two steps procedure is described useful to insert functional groups to the hyaluronic acid (HA), through the formation, in organic solvent, of a particular active group on hydroxyl groups of HA and subsequent substitution, on the inserted active group, with a pendant portion containing at least in its terminal portion a nucleophilic functional group, NH2—R. The group inserted by nucleophilic substitution can contain in another its terminal portion a further nucleophilic functional group, in a way to be easily exploitable to further chemical functionalizations, such as an example to obtain the methacrylation of HA functional groups, to obtain photocrosslinkable derivatives. Both direct derivatives of the proposed process and those obtained by the further functionalization can be employed to produce hydrogels.
    Type: Grant
    Filed: January 30, 2009
    Date of Patent: October 14, 2014
    Assignee: Universita' Degli Studi di Palermo
    Inventors: Gaetano Giammona, Fabio Palumbo, Giovanna Pitarresi
  • Patent number: 8529935
    Abstract: The present invention relates to hydrogels endowed with antibacterial properties, to be used for injection in damaged bones or in the production of antibacterial coatings of prostheses for implant in the human or animal body, obtained by loading with antibacterial agents hydrogels formed by derivatives of hyaluronic acid; the invention also relates to a kit of parts for producing the antibacterial hydrogels.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: September 10, 2013
    Assignees: Mero S.R.L., Novagenit S.R.L.
    Inventors: Gaetano Giammona, Giovanna Pitarresi, Fabio Palumbo, Carlo Luca Romano, Enzo Meani, Edgardo Cremascoli
  • Patent number: 8518606
    Abstract: The catalyst thin layer consists of electronically conductive catalyst nano-particles embedded in a polymeric matrix. The ratio number of catalyst atoms/total number of atoms in the catalyst layer is comprised between 40% and 90%, more preferably between 50% and 60%.
    Type: Grant
    Filed: November 12, 2008
    Date of Patent: August 27, 2013
    Assignees: Commissariat a l'energie Atomique et aux Energies Alternatives, Universita Degli Studi di Bari
    Inventors: Steve Martin, Riccardo D'agostino, Antoine Latour, Antonella Milella, Fabio Palumbo, Jessica Thery
  • Publication number: 20130129800
    Abstract: The present invention relates to hydrogels based on hyaluronic acid based derivatives, that are more resistant than hyaluronic acid alone towards chemical and enzymatic degradation and are endowed with a mix of chemical and mechanical properties such that they are of optimal use in several surgeries, for instance for injection in bone fractures or cavities and for the production of coatings of prostheses in orthopedic surgery, as fillers in cosmetic and maxillo-facial surgery, as anti-adhesion barrier in the prevention of postoperative adhesions in abdominal and abdominal/pelvic surgery, and in general surgery. These hydrogels can be loaded with several different kinds of compounds having pharmacological and biological activity, that are then released from the hydrogel in the site of intervention.
    Type: Application
    Filed: July 29, 2011
    Publication date: May 23, 2013
    Applicants: MERO S.R.L., NOVAGENIT S.R.L
    Inventors: Gaetano Giammona, Giovanna Pitarresi, Fabio Palumbo, Carlo Luca Romano', Enzo Meani, Edgardo Cremascoli
  • Publication number: 20110280921
    Abstract: The present invention relates to hydrogels endowed with antibacterial properties, to be used for injection in damaged bones or in the production of antibacterial coatings of prostheses for implant in the human or animal body, obtained by loading with antibacterial agents hydrogels formed by derivatives of hyaluronic acid; the invention also relates to a kit of parts for producing the antibacterial hydrogels.
    Type: Application
    Filed: January 29, 2010
    Publication date: November 17, 2011
    Applicants: NOVAGENIT S.R.L., MERO S.R.L
    Inventors: Gaetano Giammona, Giovanna Pitarresi, Fabio Palumbo, Carlo Luca Romano, Enzo Meani, Edgardo Cremascoli
  • Publication number: 20110236486
    Abstract: A system and method are provided for controlling an internal combustion engine driving a generator/welder or a stand-alone generator. Controlling the engine may include altering the engine speed based upon a detected demand on the generator and/or operating parameters of a welder. For example, the engine speed may be increased based on a detected draw on the generator and/or the operating parameters of the welder. In addition, the engine speed may be automatically decreased to a non-standard idle speed or the engine may be automatically turned off if no demand is detected for a period of time. Additionally, the engine speed may be increased if only frequency-insensitive demands are detected on the generator. Combinations of these and further methods may be executed. Various devices are provided for implementing the above methods.
    Type: Application
    Filed: November 30, 2009
    Publication date: September 29, 2011
    Inventors: Gaetano Giammona, Fabio Palumbo, Giovanna Pitarresi
  • Publication number: 20110217628
    Abstract: The catalyst thin layer consists of electronically conductive catalyst nano-particles embedded in a polymeric matrix. The ratio number of catalyst atoms/total number of atoms in the catalyst layer is comprised between 40% and 90%, more preferably between 50% and 60%.
    Type: Application
    Filed: November 12, 2008
    Publication date: September 8, 2011
    Applicants: COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES, UNIVERSITA DEGLI STUDI DI BARI
    Inventors: Steve Martin, Riccardo D'agostino, Antoine Latour, Antonella Milella, Fabio Palumbo, Jessica Thery
  • Publication number: 20040044645
    Abstract: The invention relates to a method for supplying data and/or code segments to a local computer, in a distributed computer network, during loading of a first page of information present on a remote computer belonging to said network and requested by said local computer, said first page including a plurality of sequential commands for a read/execute program resident on said local computer, comprising the steps of:
    Type: Application
    Filed: July 31, 2003
    Publication date: March 4, 2004
    Inventors: Fabio Palumbo, Marcovaleno Iannicca