Patents by Inventor Fabio Polato

Fabio Polato has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Isolation of Phosphoproteins, Glycoproteins and Fragments thereof
    Publication number: 20140329991
    Abstract: The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. A lanthanide metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for many types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics.
    Type: Application
    Filed: January 17, 2013
    Publication date: November 6, 2014
    Inventors: Matthias Rainer, Fabio Polato, Douglas T. Gjerde, Guenther Bonn
  • Isolation of phosphoproteins, glycoproteins and fragments thereof
    Patent number: 8835612
    Abstract: The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. Metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for several types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics.
    Type: Grant
    Filed: October 10, 2011
    Date of Patent: September 16, 2014
    Inventors: Fabio Polato, Mathias Rainer, Douglas T. Gjerde, Guenther Bonn
  • Isolation of Phosphoproteins, Glycoproteins and Fragments thereof
    Publication number: 20140200330
    Abstract: The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. A lanthanide metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for many types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics.
    Type: Application
    Filed: January 17, 2013
    Publication date: July 17, 2014
    Inventors: Matthias Rainer, Fabio Polato, Douglas T. Gjerde, Guenther Bonn
  • Isolation of Phosphoproteins, Glycoproteins and Fragments thereof
    Publication number: 20120088906
    Abstract: The invention provides methods and apparatus for the selective isolation of phosphorylated and glycosylated proteins and their fragments. Metal cation is used to precipitate proteins or protein fragments containing phospho groups and/or glyco groups. The sample preparation method can be used for several types of biological samples, including HeLa cells, food, and human cerebrospinal fluid. The proteins are isolated, recovered and ready for analysis by mass spectrometry or other analytical methods allowing detection limits down to the femtomole level. The method and apparatus are valuable tools in the field of protein analysis and diagnostics.
    Type: Application
    Filed: October 10, 2011
    Publication date: April 12, 2012
    Inventors: Fabio Polato, Mathias Rainer, Douglas T. Gjerde, Guenther Bonn