Patents by Inventor Fabio Prati

Fabio Prati has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods of treating of bacterial infections with ?-lactamase inhibitors
    Patent number: 10335425
    Abstract: A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one ?-lactam antibiotic and at least one triazolylmethyl boronic acid.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: July 2, 2019
    Assignee: CASE WESTERN RESERVE UNIVERSITY
    Inventors: Robert Bonomo, Fabio Prati, Emilia Caselli, Chiara Romagnoli
  • COMPOSITIONS AND METHODS OF TREATING OF BACTERIAL INFECTIONS WITH BETA-LACTAMASE INHIBITORS
    Publication number: 20180256614
    Abstract: A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one ?-lactam antibiotic and at least one triazolylmethyl boronic acid.
    Type: Application
    Filed: April 24, 2018
    Publication date: September 13, 2018
    Inventors: Robert Bonomo, Fabio Prati, Emilia Caselli, Chiara Romagnoli
  • Compositions and methods of treating of bacterial infections with ?-lactamase inhibitors
    Patent number: 9949995
    Abstract: A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one ?-lactam antibiotic and at least one triazolylmethyl boronic acid.
    Type: Grant
    Filed: September 6, 2016
    Date of Patent: April 24, 2018
    Assignee: Case Western Reserve University
    Inventors: Robert Bonomo, Fabio Prati, Emilia Caselli, Chiara Romagnoli
  • COMPOSITIONS AND METHODS OF TREATING OF BACTERIAL INFECTIONS WITH BETA-LACTAMASE INHIBITORS
    Publication number: 20170065626
    Abstract: A method of treating a bacterial infection in a subject in need thereof includes administering to the subject therapeutically effective amounts of at least one ?-lactam antibiotic and at least one triazolylmethyl boronic acid.
    Type: Application
    Filed: September 6, 2016
    Publication date: March 9, 2017
    Inventors: Robert Bonomo, Fabio Prati, Emilia Caselli, Chiara Romagnoli
  • ?-lactamase inhibitors
    Patent number: 9371337
    Abstract: Disclosed herein inter alia are Boron containing compounds and methods for treating infections related to antibiotic resistant microorganisms.
    Type: Grant
    Filed: April 14, 2014
    Date of Patent: June 21, 2016
    Assignees: The Regents of the University of California, Universita' degli Studi di Modena e Reggio Emilia
    Inventors: Brian K. Shoichet, Fabio Prati, Emilia Caselli, Chiara Romagnoli, Oliv Eidam
  • BETA-LACTAMASE INHIBITORS
    Publication number: 20140315861
    Abstract: Disclosed herein inter alia are Boron containing compounds and methods for treating infections related to antibiotic resistant microorganisms.
    Type: Application
    Filed: April 14, 2014
    Publication date: October 23, 2014
    Applicants: The Regents of the University of California, Universita' Degli Studi di Modena e Reggio Emilia
    Inventors: Brian K. Shoichet, Fabio Prati, Emilia Caselli, Chiara Romagnoli, Oliv Eidam
  • Nanomolar ?-lactamase inhibitors
    Patent number: 7271186
    Abstract: New carboxyphenyl-glycylboronic acid transition-state analog inhibitors, representative of a class of compounds effective against class C ?-lactamase AmpC. The new compounds improve inhibition by over two-orders of magnitude compared to analogous glycylboronic acids, with Ki values as low as 1 nM.
    Type: Grant
    Filed: December 9, 2003
    Date of Patent: September 18, 2007
    Assignees: Northwestern University, University of Modena
    Inventors: Brian K. Shoichet, Fabio Prati