Patents by Inventor Fabio Santos

Fabio Santos has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240150379
    Abstract: Tri-component multi-functional boronated complexes (B-complexes), featuring reversible covalent bonds, are described, which incorporate a drug; a water-soluble moiety (e.g. polyethylene glycol (PEG) chains, cyclodextrins); and a targeting unit. A B-complex core was assembled in one step, and proved to be stable in different biocompatible conditions, such as human plasma, though reversible for example in the presence of glutathione (GSH). This platform enabled the modular construction of the multifunctional conjugates exhibiting high selectivity towards, for example, folate-receptor-positive MDA-MB-231 cancer cells, having an IC50 in the low nanomolar range.
    Type: Application
    Filed: December 13, 2023
    Publication date: May 9, 2024
    Inventors: Pedro GOIS, Fabio SANTOS
  • Patent number: 11912397
    Abstract: Thermally configurable structural elements (e.g., aircraft components such as an aircraft winglet spar) capable of assuming at least first and second structural configurations are provided whereby the structural element includes an integral actuation mechanism may be formed of sintered shape memory alloy (SMA) particles and sintered non-SMA particles formed by an additive layer manufacturing (ALM) process, such as 3D printing. The ALM process thereby provides by at least one thermally configurable region, and at least one non-thermally configurable region which is unitarily contiguous with the at least one thermally configurable region. The at least one thermally configurable region is capable of assuming at least first and second positional orientations in response to the presence or absence of a thermal input to thereby cause the structural element to assume the at least first and second structural configurations, respectively.
    Type: Grant
    Filed: October 27, 2022
    Date of Patent: February 27, 2024
    Assignee: EMBRAER S.A.
    Inventors: Paulo Anchieta da Silva, Fabio Santos da Silva, Danillo Cafaldo dos Reis
  • Patent number: 11884687
    Abstract: Tri-component multi-functional boronated complexes (B-complexes), featuring reversible covalent bonds, are described, which incorporate a drug; a water-soluble moiety (e.g. polyethylene glycol (PEG) chains, cyclodextrins); and a targeting unit. A B-complex core was assembled in one step, and proved to be stable in different biocompatible conditions, such as human plasma, though reversible for example in the presence of glutathione (GSH). This platform enabled the modular construction of the multifunctional conjugates exhibiting high selectivity towards, for example, folate-receptor-positive MDA-MB-231 cancer cells, having an IC50 in the low nanomolar range.
    Type: Grant
    Filed: March 1, 2018
    Date of Patent: January 30, 2024
    Assignee: Hovione Scientia Limited
    Inventors: Pedro Gois, Fabio Santos
  • Publication number: 20230057985
    Abstract: Thermally configurable structural elements (e.g., aircraft components such as an aircraft winglet spar) capable of assuming at least first and second structural configurations are provided whereby the structural element includes an integral actuation mechanism may be formed of sintered shape memory alloy (SMA) particles and sintered non-SMA particles formed by an additive layer manufacturing (ALM) process, such as 3D printing. The ALM process thereby provides by at least one thermally configurable region, and at least one non-thermally configurable region which is unitarily contiguous with the at least one thermally configurable region. The at least one thermally configurable region is capable of assuming at least first and second positional orientations in response to the presence or absence of a thermal input to thereby cause the structural element to assume the at least first and second structural configurations, respectively.
    Type: Application
    Filed: October 27, 2022
    Publication date: February 23, 2023
    Inventors: Paulo Anchieta da SILVA, Fabio Santos da SILVA, Danillo Cafaldo dos REIS
  • Patent number: 11492096
    Abstract: Noise-abatement for a leading edge wing slat is provided by a noise-abatement airflow shield integral with the lower trailing edge of the slat, wherein the shield is reciprocally autonomously curveable from a substantially planar configuration when the slat is in a retracted position thereof and into a convexly curved configuration when the slat is in a deployed position thereof.
    Type: Grant
    Filed: September 1, 2017
    Date of Patent: November 8, 2022
    Assignees: EMBRAER S.A., USP—UNIVERSIDADE DE SÃO PAULO
    Inventors: Danillo Cafaldo Dos Reis, Leandro Guilherme Crenite Simões, Micael Gianini Valle Do Carmo, Fábio Santos Da Silva, Eduardo Lobão Capucho Coelho, Leandro Souza De Moura Lima, Paulo Anchieta Da Silva, Fernando Martini Catalano, Cecil Wagner Skaleski, Francisco Keller Klug, Marcus Felipe Hori Ochi
  • Publication number: 20200346735
    Abstract: Noise-abatement for a leading edge wing slat is provided by a noise-abatement airflow shield integral with the lower trailing edge of the slat, wherein the shield is reciprocally autonomously curvable from a substantially planar configuration when the slat is in a retracted position thereof and into a convexly curved configuration when the slat is in a deployed position thereof.
    Type: Application
    Filed: September 1, 2017
    Publication date: November 5, 2020
    Inventors: Danillo Cafaldo DOS REIS, Leandro Guilherme CRENITE SIMÕES, Micael Gianini, Valle DO CARMO, Fábio Santos DA SILVA, Eduardo Lobão CAPUCHO COELHO, Leandro Souza DE MOURA LIMA, Paulo Anchieta DA SILVA, Fernando MARTINI CATALANO, Cecil WAGNER SKALESKI, Francisco KELLER KLUG, Marcus Felipe HORI OCHI
  • Patent number: 10766622
    Abstract: Lightweight passenger seats that are especially adapted for use in aircraft cabins. The seats will include a seat back and a seat bottom having a basin which defines a recessed central interior space, a plurality of straps having opposed ends connected to respective upper edge regions of the basin so as to be positioned under tension over the recessed central interior space; and a cover cushion covering the straps and connected to the basin. The seat back may be connected at opposed sides thereof to upright support members adjacent a lumbar region thereof so as to establish an upper region of the seat back above the lumbar region which is capable of being resiliently flexed between upright and rearwardly inclined positions.
    Type: Grant
    Filed: October 22, 2018
    Date of Patent: September 8, 2020
    Assignee: YABORÃ INDÚSTRIA AERONÁUTICA S.A.
    Inventors: Ricardo Athayde Abelheira, Flavia Renata Dantas Alves Silva Ciaccia, Fábio Santos da Silva, Rodrigo Takashi Lourenço Kawasaki, Moacir Morais de Andrade Lima, Fabiano Mafra Decarli, Demetrio Andrade de Campos
  • Patent number: 10677229
    Abstract: Exemplary embodiments are directed to thermally driven actuator systems including a thermally driven element and one or more heating elements coupled to and in thermal contact with the thermally driven element. The thermally driven element can be capable of being selectively reconfigured in shape based on a thermal strain or temperature driven phase change. The one or more heating elements can be configured to selectively and independently apply heat to one or more of a plurality of different regions of the thermally driven element to selectively raise a temperature or temperatures of the selected region or regions of the thermally driven element to selectively reconfigure the shape of the thermally driven element.
    Type: Grant
    Filed: March 2, 2018
    Date of Patent: June 9, 2020
    Assignees: Metis Design Corporation, Embraer S.A.
    Inventors: Seth S. Kessler, Fabio Santos da Silva, Rodrigo Carlana da Silva, Cassio Wallner, Paulo Anchieta da Silva, Estelle Cohen
  • Publication number: 20200164963
    Abstract: Thermally configurable structural elements (e.g., aircraft components such as an aircraft winglet spar) capable of assuming at least first and second structural configurations are provided whereby the structural element includes an integral actuation mechanism provided by at least one thermally configurable region, and at least one non-thermally configurable region which is unitarily contiguous with the at least one thermally configurable region. The at least one thermally configurable region is capable of assuming at least first and second positional orientations in response to the presence or absence of a thermal input to thereby cause the structural element to assume the at least first and second structural configurations, respectively. The thermally and non-thermally configurable regions may be formed of sintered shape memory alloy (SMA) particles and sintered non-SMA particles formed by an additive layer manufacturing (ALM) process, such as 3D printing.
    Type: Application
    Filed: November 26, 2018
    Publication date: May 28, 2020
    Inventors: Paulo Anchieta da SILVA, Fabio Santos da SILVA, Danillo Cafaldo dos REIS
  • Publication number: 20200010484
    Abstract: Tri-component multi-functional boronated complexes (B-complexes), featuring reversible covalent bonds, are described, which incorporate a drug; a water-soluble moiety (e.g. polyethylene glycol (PEG) chains, cyclodextrins); and a targeting unit. A B-complex core was assembled in one step, and proved to be stable in different biocompatible conditions, such as human plasma, though reversible for example in the presence of glutathione (GSH). This platform enabled the modular construction of the multifunctional conjugates exhibiting high selectivity towards, for example, folate-receptor-positive MDA-MB-231 cancer cells, having an IC50 in the low nanomolar range.
    Type: Application
    Filed: March 1, 2018
    Publication date: January 9, 2020
    Inventors: Pedro GOIS, Fabio SANTOS
  • Patent number: 10462327
    Abstract: Examples disclosed herein relate to receiving a document comprising a plurality of document elements, removing a first document element of the plurality of document elements from the document, re-positioning a second document element of the plurality of document elements in the document, and inserting a new document element comprising a link to a source of the document.
    Type: Grant
    Filed: May 13, 2016
    Date of Patent: October 29, 2019
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Marlon Gomes Lopes, Leandro Hernandes Manica, Fabio Santos Nallem
  • Publication number: 20190163725
    Abstract: Examples disclosed herein relate to content resizing. An example method can include identifying an input content boundary of content in an input document file based on internal structure data of the input document file. The example method may also include storing a received user input of preferences for a new size and a detected rotation for an output document file. The example method may also include generating a calculated ratio between an input document display size and an output document display size. In an example, the method may include mapping a coordinate system to each point of the input content boundary. In an example, the method may also include drawing output content into the output document file by applying the calculated ratio and the detected rotation for the output document file to the mapped coordinate system of the content in the input content boundary.
    Type: Application
    Filed: July 28, 2016
    Publication date: May 30, 2019
    Inventors: Dalmir Antonio da Silva, Fabio Santos Nallem, Lucas Dalmedico Gessoni, Ronaldo Canesqui, Peter Pennings, Patricia Teixeira, Natalia Campagnoli Franchi, Luiz Rafael de Souza, Julio Cesar Soares do Nascimento, Fabio Fernando de Lima Pereira, Douglas Cesar Pampu, Danilo Monteiro de Souza, Andre Luiz Teodoro, Adilson Dutra Teixeira Filho
  • Publication number: 20190118951
    Abstract: Lightweight passenger seats that are especially adapted for use in aircraft cabins. The seats will include a seat back and a seat bottom having a basin which defines a recessed central interior space, a plurality of straps having opposed ends connected to respective upper edge regions of the basin so as to be positioned under tension over the recessed central interior space; and a cover cushion covering the straps and connected to the basin. The seat back may be connected at opposed sides thereof to upright support members adjacent a lumbar region thereof so as to establish an upper region of the seat back above the lumbar region which is capable of being resiliently flexed between upright and rearwardly inclined positions.
    Type: Application
    Filed: October 22, 2018
    Publication date: April 25, 2019
    Inventors: Ricardo Athayde ABELHEIRA, Flavia Renata Dantas Alves Silva CIACCIA, Fábio Santos da SILVA, Rodrigo Takashi Lourenço KAWASAKI, Moacir Morais de ANDRADE LIMA, Fabiano Mafra DECARLI, Demetrio Andrade de CAMPOS
  • Publication number: 20190037098
    Abstract: Examples disclosed herein relate to receiving a document comprising a plurality of document elements, removing a first document element of the plurality of document elements from the document, re-positioning a second document element of the plurality of document elements in the document, and inserting a new document element comprising a link to a source of the document.
    Type: Application
    Filed: May 13, 2016
    Publication date: January 31, 2019
    Applicant: Hewlett-Packard Development Company, L.P.
    Inventors: Marlon Gomes LOPES, Leandro Hernandes MANICA, Fabio Santos NALLEM
  • Publication number: 20180258920
    Abstract: Exemplary embodiments are directed to thermally driven actuator systems including a thermally driven element and one or more heating elements coupled to and in thermal contact with the thermally driven element. The thermally driven element can be capable of being selectively reconfigured in shape based on a thermal strain or temperature driven phase change. The one or more heating elements can be configured to selectively and independently apply heat to one or more of a plurality of different regions of the thermally driven element to selectively raise a temperature or temperatures of the selected region or regions of the thermally driven element to selectively reconfigure the shape of the thermally driven element.
    Type: Application
    Filed: March 2, 2018
    Publication date: September 13, 2018
    Inventors: Seth S. Kessler, Fabio Santos da Silva, Rodrigo Carlana da Silva, Cassio Wallner, Paulo Anchieta da Silva, Estelle Cohen
  • Patent number: 10072358
    Abstract: The present patent of invention describes a recycling process to recover fibrous reinforcing material of composite materials, particularly carbon fiber, primary reactor compound (101), for the controlled pyrolysis and oxidation of the composite material matrix (resin) at low temperature (400° C. to 500° C.) and a system for treating waste gases produced by thermal decomposition of composite material matrixes which employs a secondary reactor (201), containing within the same a thermal plasma arc (211). The main characteristic of the process, within the scope of the carbon fiber recycling, is the possibility of maintaining the fabric web, obtaining fabrics made of pure carbon fiber, without a significant amount of residues and preserving their structural characteristics. The thermal plasma allows managing high temperatures (2,000° C. to 15,000° C.
    Type: Grant
    Filed: November 18, 2015
    Date of Patent: September 11, 2018
    Assignee: EMBRAER S.A.
    Inventors: Antônio Carlos Da Cruz, Fábio Santos Da Silva, Rafael Razuk Garcia
  • Patent number: 10072992
    Abstract: Systems and a method for measuring at least one mechanical force in a stator of an electrical machine are provided. The stator of the electrical machine includes a multiple stacked metal lamina. At least one fiber Bragg grating (FBG) element is placed between two of the lamina, such as in a rotor-facing tooth of the lamina.
    Type: Grant
    Filed: September 29, 2015
    Date of Patent: September 11, 2018
    Assignee: SIEMENS INDUSTRY SOFTWARE NV
    Inventors: Cassio Faria, Fabio Santos
  • Patent number: 9619438
    Abstract: Techniques pertaining to embedding fonts in a PDF document are disclosed. A processing component executing a PDF application programming interface (API) may be operative to identify each character in a PDF file associated with an un-embedded font. The PDF API may store a bitmap representation for each identified character in the PDF file associated with the un-embedded font. The PDF API may then create a bitmap font character from the bitmap representation for each identified character in the PDF file associated with an un-embedded font and replace each reference to a character in the PDF file associated with an un-embedded font with a reference to its corresponding bitmap font character.
    Type: Grant
    Filed: January 30, 2013
    Date of Patent: April 11, 2017
    Assignee: Hewlett-Packard Development Company, L. P.
    Inventors: Veronica Andrade Aveline Nunes, Marcelo Aita Riss, Fabio Santos Nallem, Jon Brewster, Catherine K Flager, Marcelo Peres, Arthur Zanardi, Danilo deSousa, Leticia Silva, Lucas Gessoni, Leonardo Domingues, Marcia dosSantos
  • Publication number: 20160153123
    Abstract: The present patent of invention describes a recycling process to recover fibrous reinforcing material of composite materials, particularly carbon fiber, primary reactor compound (101), for the controlled pyrolysis and oxidation of the composite material matrix (resin) at low temperature (400° C. to 500° C.) and a system for treating waste gases produced by thermal decomposition of composite material matrixes which employs a secondary reactor (201), containing within the same a thermal plasma arc (211). The main characteristic of the process, within the scope of the carbon fiber recycling, is the possibility of maintaining the fabric web, obtaining fabrics made of pure carbon fiber, without a significant amount of residues and preserving their structural characteristics. The thermal plasma allows managing high temperatures (2,000° C. to 15,000° C.
    Type: Application
    Filed: November 18, 2015
    Publication date: June 2, 2016
    Inventors: Antônio Carlos DA CRUZ, Fábio Santos DA SILVA, Rafael Razuk GARCIA
  • Patent number: D882975
    Type: Grant
    Filed: October 23, 2017
    Date of Patent: May 5, 2020
    Assignee: EMBRAER S.A.
    Inventors: Ricardo Athayde Abelheira, Flavia Renata Dantas Alves Silva Ciaccia, Fábio Santos da Silva, Rodrigo Takashi Lourenço Kawasaki, Moacir Morais de Andrade Lima, Fabiano Mafra Decarli, Demetrio Andrade de Campos