Patents by Inventor Fabio Spreafico

Fabio Spreafico has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipases and uses thereof
    Patent number: 8216586
    Abstract: The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel lipolytic enzyme from Aspergillus niger The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel lipolytic enzyme as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a lipolytic enzyme according to the invention is genetically modified to enhance its activity and/or level of expression.
    Type: Grant
    Filed: May 6, 2009
    Date of Patent: July 10, 2012
    Assignee: DSM IP Assets B.V.
    Inventors: Richard Albang, Andreas Fritz, Oliver Heinrich, Hilmar Ilgenfritz, Dieter Maier, Christian Wagner, Ulrike Folkers, Beatrix Gerhard, Fabio Spreafico, Lex De Boer, Roelf Bernhard Meima
  • Phospholipases and uses thereof
    Patent number: 7838274
    Abstract: The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel phospholipase isolated from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel phospholipase as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a phospholipase according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: November 23, 2010
    Assignee: DSM IP Assets B.V.
    Inventors: Kaj Albermann, Wolfram Kemmner, Dieter Maier, Fabio Spreafico, Alexander Stock, Christian Wagner, Lex De Boer, Roelf Bernhard Meima
  • Novel phospholipases and uses thereof
    Publication number: 20100047877
    Abstract: The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel phospholipase isolated from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel phospholipase as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a phospholipase according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
    Type: Application
    Filed: August 6, 2009
    Publication date: February 25, 2010
    Applicant: DSM IP ASSETS B.V.
    Inventors: Kaj Albermann, Wolfram Kemmner, Dieter Maier, Fabio Spreafico, Alexander Stock, Christian Wagner, Lex De Boer, Roelf Bernhard Meima
  • Novel genes encoding novel proteolytic enzymes
    Publication number: 20090275079
    Abstract: The invention relates to newly identified gene sequences that encode novel proteases obtainable from Aspergillus niger. The invention features the full length gene sequence of the novel genes, their cDNA sequences as well as the full-length functional protein and fragments thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with DNA according to the invention and cells wherein a protease according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
    Type: Application
    Filed: October 25, 2007
    Publication date: November 5, 2009
    Applicant: DSM IP ASSETS B.V.
    Inventors: Luppo Edens, Alard Van Albertus Dijk, Phillip Krubasik, Kaj Albermann, Alexander Stock, Erik Kimpel, Sabrine Klaubauer, Christian Wagner, Andreas Fritz, Wilk Von Gustedt, Oliver Henrich, Dieter Maier, Fabio Spreafico, Ulrike Folkers, Sylvia Hopper, Wolfram Kemmner, Pamela Tan, Josephine Stiebler, Ricahrd Albang
  • Novel lipases and uses thereof
    Publication number: 20090232936
    Abstract: The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel lipolytic enzyme from Aspergillus niger The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel lipolytic enzyme as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a lipolytic enzyme according to the invention is genetically modified to enhance its activity and/or level of expression.
    Type: Application
    Filed: May 6, 2009
    Publication date: September 17, 2009
    Applicant: DSM IP ASSETS B.V.
    Inventors: Richard Albang, Andreas Fritz, Oliver Heinrich, Hilmar Ilgenfritz, Dieter Maier, Christian Wagner, Ulrike Folkers, Beatrix Gerhard, Fabio Spreafico, Lex De Boer, Roelf Bernhard Meima
  • Phospholipases and uses thereof
    Patent number: 7588925
    Abstract: The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel phospholipase isolated from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel phospholipase as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a phospholipase according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
    Type: Grant
    Filed: October 10, 2006
    Date of Patent: September 15, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Kaj Albermann, Wolfram Kemmner, Dieter Maier, Fabio Spreafico, Alexander Stock, Christian Wagner, Lex De Boer, Roelf Bernhard Meima
  • Lipases and uses thereof
    Patent number: 7550280
    Abstract: The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel lipolytic enzyme from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel lipolytic enzyme as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a lipolytic enzyme according to the invention is genetically modified to enhance its activity and/or level of expression.
    Type: Grant
    Filed: August 15, 2003
    Date of Patent: June 23, 2009
    Assignee: DSM IP Assets B.V.
    Inventors: Richard Albang, Andreas Fritz, Oliver Heinrich, Hilmar Ilgenfritz, Dieter Maier, Christian Wagner, Ulrike Folkers, Beatrix Gerhard, Fabio Spreafico, Lex De Boer, Roelf Bernhard Meima
  • Genes encoding novel proteolytic enzymes
    Patent number: 7323327
    Abstract: The invention relates to newly identified gene sequences that encode novel proteases obtainable from Aspergillus niger. The invention features the full length gene sequence of the novel genes, their cDNA sequences as well as the full-length functional protein and fragments thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with DNA according to the invention and cells wherein a protease according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
    Type: Grant
    Filed: February 22, 2002
    Date of Patent: January 29, 2008
    Assignee: DSM IP Assets B.V.
    Inventors: Luppo Edens, Albertus Van Dijk, Philipp Krubasik, Kaj Albermann, Alexander Stock, Erik Kimpel, Sabine Klugbauer, Christian Wagner, Andreas Fritz, Wilk Von Gustedt, Oliver Heinrich, Dieter Maier, Fabio Spreafico, Ulrike Folkers, Sylvia Hopper, Wolfram Kemmner, Pamela Tan, Josephine Stiebler, Richard Albang
  • Novel phospholipases and uses thereof
    Publication number: 20070207521
    Abstract: The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel phospholipase isolated from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel phospholipase as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a phospholipase according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
    Type: Application
    Filed: October 10, 2006
    Publication date: September 6, 2007
    Applicant: DSM IP ASSETS B.V.
    Inventors: Kaj Albermann, Wolfram Kemmner, Dieter Maier, Fabio Spreafico, Alexander Stock, Christian Wagner, Lex De Boer, Roelf Meima
  • Novel lipases and uses thereof
    Publication number: 20060281080
    Abstract: The invention relates to a newly identified polynucleotide sequence comprising a gene that encodes a novel lipolytic enzyme from Aspergillus niger. The invention features the full length nucleotide sequence of the novel gene, the cDNA sequence comprising the full length coding sequence of the novel lipolytic enzyme as well as the amino acid sequence of the full-length functional protein and functional equivalents thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with a polynucleotide according to the invention and cells wherein a lipolytic enzyme according to the invention is genetically modified to enhance its activity and/or level of expression.
    Type: Application
    Filed: August 15, 2003
    Publication date: December 14, 2006
    Inventors: Richard Albang, Andreas Fritz, Oliver Heinrich, Hilmar Ilgenfritz, Dieter Maier, Christian Wagner, Ulrike Folkers, Beatrix Gerhard, Fabio Spreafico, Lex De Boer, Roelf Meima
  • Novel Genes Encoding Novel Proteolytic Enzymes
    Publication number: 20050064403
    Abstract: The invention relates to newly identified gene sequences that encode novel proteases obtainable from Aspergillus niger. The invention features the full length gene sequence of the novel genes, their cDNA sequences as well as the full-length functional protein and fragments thereof. The invention also relates to methods of using these enzymes in industrial processes and methods of diagnosing fungal infections. Also included in the invention are cells transformed with DNA according to the invention and cells wherein a protease according to the invention is genetically modified to enhance or reduce its activity and/or level of expression.
    Type: Application
    Filed: February 22, 2002
    Publication date: March 24, 2005
    Inventors: Luppo Edens, Dijk Alard, Philipp Krubasik, Kaj Albermann, Stock Alexander, Erik Kimpel, Sabine Klugbauer, Christian Wagner, Andreas Fritz, Gustedt Wilk, Oliver Heinrich, Dieter Maier, Fabio Spreafico, Ulrike Folkers, Sylvia Hopper, Wolfram Kemmner, Pamela Tan, Josephine Stiebler, Richard Albang