Patents by Inventor Fabrice Berrué
Fabrice Berrué has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230227489Abstract: Surfactants based on a newly discovered class of compounds include a hydrophobic lipid oligomer covalently linked to a peptide or peptide-like chain and a carbohydrate moiety, and a serine-leucinol dipeptide linked to the lipid oligomer. Such surfactants can be used to create an oil-in-water or water-in-oil emulsion by mixing together a polar component; a non-polar component; and the surfactant. Biosurfactants of the newly discovered class can be made by isolating and culturing a microorganism which produces the biosurfactant, and then isolating the biosurfactant from the culture. A microorganism can be engineered to produce biosurfactant of this newly discovered class by expressing a set of heterologous genes involved in the biosynthesis of the biosurfactant in the microorganism.Type: ApplicationFiled: January 20, 2023Publication date: July 20, 2023Applicant: Croda International PlcInventors: Russell Greig Kerr, Bradley Arnold Haltli, Douglas Hubert Marchbank, Fabrice Berrué
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Patent number: 11608352Abstract: Surfactants based on a newly discovered class of compounds include a hydrophobic lipid oligomer covalently linked to a peptide or peptide-like chain and a carbohydrate moiety, and a serine-leucinol dipeptide linked to the lipid oligomer. Such surfactants can be used to create an oil-in-water or water-in-oil emulsion by mixing together a polar component; a non-polar component; and the surfactant. Biosurfactants of the newly discovered class can be made by isolating and culturing a microorganism which produces the biosurfactant, and then isolating the biosurfactant from the culture. A microorganism can be engineered to produce biosurfactant of this newly discovered class by expressing a set of heterologous genes involved in the biosynthesis of the biosurfactant in the microorganism.Type: GrantFiled: March 12, 2020Date of Patent: March 21, 2023Assignee: CRODA INTERNATIONAL PLCInventors: Russell Greig Kerr, Bradley Arnold Haltli, Douglas Hubert Marchbank, Fabrice Berruè
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Patent number: 10898421Abstract: Use of pycnidione, epolone A, and epolone B as anti-dandruff actives either alone or in combination in anti-dandruff compositions, particularly shampoos and conditioners. The actives are particularly effective against Malassezia yeasts and Malassezia furfur. A method of obtaining pycnidione, epolone A, and epolone B from culturing of Neosetophoma samarorum is also described.Type: GrantFiled: June 8, 2016Date of Patent: January 26, 2021Inventors: Russell Greig Kerr, David Patrick Overy, Fabrice Berrué
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Patent number: 10888548Abstract: Anti-Dandruff Agents A novel anti-dandruff composition comprising spirofuranone-lactam tetramic acid or derivatives thereof, and optionally at least one biologically derivable meroterpene. The spirofuranone-lactam tetramic acid is preferably a bio-active heterospirocyclic secondary metabolite of Aspergillus, such as pseurotin A. The biologically derivable meroterpene may be selected from fumagillin, fumagillin derivative, chlovalicin, or ovalicin. Use of said agents as anti-dandruff actives in anti-dandruff compositions, particularly shampoos and conditioners is also provided. The active is particularly effective against Malassezia yeasts and Malassezia furfur which may cause dandruff. A method of obtaining the anti-dandruff actives from culturing of Peyronellaea sp. strain RKDO347 is also described.Type: GrantFiled: June 8, 2016Date of Patent: January 12, 2021Assignee: Croda International PlcInventors: Russell Greig Kerr, David Patrick Overy, Fabrice Berrué
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Patent number: 10821064Abstract: A novel anti-dandruff agent being a fumagillin derivative according to formula (I), and use of said agent as an anti-dandruff actives in anti-dandruff compositions, particularly shampoos and conditioners. The active is particularly effective against Malassezia yeasts and Malassezia furfur which may cause dandruff. A method of obtaining the fumagillin derivative from culturing of Peyronellaea sp. strain RKDO347 is also described.Type: GrantFiled: June 8, 2016Date of Patent: November 3, 2020Assignee: CRODA INTERNATIONAL PLCInventors: Russell Greig Kerr, David Patrick Overy, Fabrice Berrué
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Publication number: 20200207799Abstract: Surfactants based on a newly discovered class of compounds include a hydrophobic lipid oligomer covalently linked to a peptide or peptide-like chain and a carbohydrate moiety, and a serine-leucinol dipeptide linked to the lipid oligomer. Such surfactants can be used to create an oil-in-water or water-in-oil emulsion by mixing together a polar component; a non-polar component; and the surfactant. Biosurfactants of the newly discovered class can be made by isolating and culturing a microorganism which produces the biosurfactant, and then isolating the biosurfactant from the culture. A microorganism can be engineered to produce biosurfactant of this newly discovered class by expressing a set of heterologous genes involved in the biosynthesis of the biosurfactant in the microorganism.Type: ApplicationFiled: March 12, 2020Publication date: July 2, 2020Applicant: Croda International PlcInventors: Russell Greig Kerr, Bradley Arnold Haltli, Douglas Hubert Marchbank, Fabrice Berruè
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Patent number: 10662221Abstract: There is provided herein compounds of formula I, wherein R1 is H or linear or branched C1-C6 lower alkyl; R2 is H, linear or branched C1-C6 lower alkyl, or a proteinogenic amino acid side chain; R3 is H, linear or branched C1-C6 lower alkyl, or a proteinogenic amino acid side chain; R4 is —OH or —O—R5 wherein R5 is linear or branched C1-C6 lower alkyl; and each R6 is independently H or —CH3; or a pharmaceutically acceptable prodrug, salt, or ester thereof. Compositions containing said compounds, and uses thereof, are also provided.Type: GrantFiled: February 2, 2016Date of Patent: May 26, 2020Assignee: UNIVERSITY OF PRINCE EDWARD ISLANDInventors: Krista Ann Gill, Fabrice Berrue, Russell Greig Kerr
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Publication number: 20190127411Abstract: Surfactants based on a newly discovered class of compounds include a hydrophobic lipid oligomer covalently linked to a peptide or peptide-like chain and a carbohydrate moiety, and a serine-leucinol dipeptide linked to the lipid oligomer. Such surfactants can be used to create an oil-in-water or water-in-oil emulsion by mixing together a polar component; a non-polar component; and the surfactant. Biosurfactants of the newly discovered class can be made by isolating and culturing a microorganism which produces the biosurfactant, and then isolating the biosurfactant from the culture. A microorganism can be engineered to produce biosurfactant of this newly discovered class by expressing a set of heterologous genes involved in the biosynthesis of the biosurfactant in the microorganism.Type: ApplicationFiled: April 6, 2017Publication date: May 2, 2019Applicant: Croda International PLCInventors: Russell Greig Kerr, Bradley Arnold Haltli, Douglas Hubert Marchbank, Fabrice Berrué
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Publication number: 20190110973Abstract: A novel anti-dandruff agent being a fumagillin derivative according to formula (I), and use of said agent as an anti-dandruff actives in anti-dandruff compositions, particularly shampoos and conditioners. The active is particularly effective against Malassezia yeasts and Malassezia furfur which may cause dandruff. A method of obtaining the fumagillin derivative from culturing of Peyronellaea sp. strain RKDO347 is also described.Type: ApplicationFiled: June 8, 2016Publication date: April 18, 2019Applicant: Croda International PLCInventors: Russell Greig Kerr, David Patrick Overy, Fabrice Berrué
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Publication number: 20180177762Abstract: Anti-Dandruff Agents A novel anti-dandruff composition comprising spirofuranone-lactam tetramic acid or derivatives thereof, and optionally at least one biologically derivable meroterpene. The spirofuranone-lactam tetramic acid is preferably a bio-active heterospirocyclic secondary metabolite of Aspergillus, such as pseurotin A. The biologically derivable meroterpene may be selected from fumagillin, fumagillin derivative, chlovalicin, or ovalicin. Use of said agents as anti-dandruff actives in anti-dandruff compositions, particularly shampoos and conditioners is also provided. The active is particularly effective against Malassezia yeasts and Malassezia furfur which may cause dandruff. A method of obtaining the anti-dandruff actives from culturing of Peyronellaea sp. strain RKDO347 is also described.Type: ApplicationFiled: June 8, 2016Publication date: June 28, 2018Applicant: Croda International PLCInventors: Russell Greig Kerr, David Patrick Overy, Fabrice Berrué
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Publication number: 20180168979Abstract: Use of pycnidione, epolone A, and epolone B as anti-dandruff actives either alone or in combination in anti-dandruff compositions, particularly shampoos and conditioners. The actives are particularly effective against Malassezia yeasts and Malassezia furfur. A method of obtaining pycnidione, epolone A, and epolone B from culturing of Neosetophoma samarorum is also described.Type: ApplicationFiled: June 8, 2016Publication date: June 21, 2018Applicant: Croda International PLCInventors: Russell Greig Kerr, David Patrick Overy, Fabrice Berrué
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Publication number: 20180155392Abstract: There is provided herein compounds of formula I, wherein R1 is H or linear or branched C1-C6 lower alkyl; R2 is H, linear or branched C1-C6 lower alkyl, or a proteinogenic amino acid side chain; R3 is H, linear or branched C1-C6 lower alkyl, or a proteinogenic amino acid side chain; R4 is ——OH or —O—R5 wherein R5 is linear or branched C1-C6 lower alkyl; and each R6 is independently H or —CH3; or a pharmaceutically acceptable prodrug, salt, or ester thereof. Compositions containing said compounds, and uses thereof, are also provided.Type: ApplicationFiled: February 2, 2016Publication date: June 7, 2018Inventors: KRISTA ANN GILL, FABRICE BERRUE, RUSSELL GREIG KERR