Patents by Inventor Fabrice Heitz

Fabrice Heitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230287106
    Abstract: Described are molecules specifically binding to human islet amyloid polypeptide (hIAPP) also known as amylin, particularly human-derived antibodies as well as fragments, derivatives and variants thereof for antagonizing islet amyloid polypeptide (IAPP) induced ?-cell damage and impaired glucose tolerance which are symptoms typically associated with diabetes mellitus type 2 (T2D).
    Type: Application
    Filed: November 9, 2022
    Publication date: September 14, 2023
    Applicants: Neurimmune Holding AG, University of Zurich
    Inventors: Jan GRIMM, Fabrice HEITZ, Fabian WIRTH, Tobias WELT
  • Publication number: 20210107972
    Abstract: Provided are novel human islet amyloid polypeptide, also known as amylin and IAPP and proIAPP respectively, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for IAPP and/or proIAPP are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for IAPP and/or proIAPP targeted immunotherapy and diagnostics, respectively.
    Type: Application
    Filed: December 7, 2020
    Publication date: April 15, 2021
    Inventors: Jan GRIMM, Fabrice HEITZ, Feng CHEN, Ioana COMBALUZIER
  • Patent number: 10882902
    Abstract: Provided are novel human islet amyloid polypeptide, also known as amylin and IAPP and proIAPP respectively, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for IAPP and/or proIAPP are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for IAPP and/or proIAPP targeted immunotherapy and diagnostics, respectively.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: January 5, 2021
    Assignee: Neurimmune Holding AG
    Inventors: Jan Grimm, Fabrice Heitz, Feng Chen, Ioana Combaluzier
  • Publication number: 20200231667
    Abstract: Described are molecules specifically binding to human islet amyloid polypeptide (hIAPP) also known as amylin, particularly human-derived antibodies as well as fragments, derivatives and variants thereof for antagonizing islet amyloid polypeptide (IAPP) induced ?-cell damage and impaired glucose tolerance winch are symptoms typically associated with diabetes mellitus type 2 (T2D).
    Type: Application
    Filed: December 5, 2019
    Publication date: July 23, 2020
    Inventors: Jan GRIMM, Fabrice HEITZ, Fabian WIRTH, Tobias WELT
  • Patent number: 10544213
    Abstract: Described are molecules specifically binding to human islet amyloid polypeptide (hIAPP) also known as amylin, particularly human-derived antibodies as well as fragments, derivatives and variants thereof for antagonizing islet amyloid polypeptide (IAPP) induced ?-cell damage and impaired glucose tolerance which are symptoms typically associated with diabetes mellitus type 2 (T2D).
    Type: Grant
    Filed: March 12, 2015
    Date of Patent: January 28, 2020
    Assignees: Neurimmune Holding AG, University of Zurich
    Inventors: Jan Grimm, Fabrice Heitz, Fabian Wirth, Tobias Welt
  • Publication number: 20180346558
    Abstract: Provided are novel human islet amyloid polypeptide, also known as amylin and IAPP and proIAPP respectively, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for IAPP and/or proIAPP are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for IAPP and/or proIAPP targeted immunotherapy and diagnostics, respectively.
    Type: Application
    Filed: August 8, 2018
    Publication date: December 6, 2018
    Inventors: Jan GRIMM, Fabrice Heitz, Feng Chen, Ioana Combaluzier
  • Patent number: 10072074
    Abstract: Provided are novel human islet amyloid polypeptide, also known as amylin and IAPP and proIAPP respectively, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for IAPP and/or proIAPP are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for IAPP and/or proIAPP targeted immunotherapy and diagnostics, respectively.
    Type: Grant
    Filed: September 7, 2016
    Date of Patent: September 11, 2018
    Assignee: Neurimmune Holding AG
    Inventors: Jan Grimm, Fabrice Heitz, Feng Chen, Ioana Combaluzier
  • Publication number: 20180179276
    Abstract: Described are molecules specifically binding to human islet amyloid polypeptide (hIAPP) also known as amylin, particularly human-derived antibodies as well as fragments, derivatives and variants thereof for antagonizing islet amyloid polypeptide (IAPP) induced ?-cell damage and impaired glucose tolerance which are symptoms typically associated with diabetes mellitus type 2 (T2D).
    Type: Application
    Filed: March 12, 2015
    Publication date: June 28, 2018
    Inventors: Jan GRIMM, Fabrice HEITZ, Fabian WIRTH, Tobias WELT
  • Publication number: 20160376354
    Abstract: Provided are novel human islet amyloid polypeptide, also known as amylin and IAPP and proIAPP respectively, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for IAPP and/or proIAPP are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for IAPP and/or proIAPP targeted immunotherapy and diagnostics, respectively.
    Type: Application
    Filed: September 7, 2016
    Publication date: December 29, 2016
    Inventors: Jan GRIMM, Fabrice Heitz, Feng Chen, Ioana Combaluzier
  • Patent number: 9475866
    Abstract: Provided are novel human islet amyloid polypeptide, also known as amylin and IAPP and proIAPP respectively, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for IAPP and/or proIAPP are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for IAPP and/or proIAPP targeted immunotherapy and diagnostics, respectively.
    Type: Grant
    Filed: September 12, 2013
    Date of Patent: October 25, 2016
    Assignee: Neurimmune Holding AG
    Inventors: Jan Grimm, Fabrice Heitz, Feng Chen, Ioana Combaluzier
  • Publication number: 20150210759
    Abstract: Provided are novel human islet amyloid polypeptide, also known as amylin and IAPP and proIAPP respectively, specific antibodies as well as fragments, derivatives and variants thereof as well as methods related thereto. Assays, kits, and solid supports related to antibodies specific for IAPP and/or proIAPP are also disclosed. The antibody, immunoglobulin chain(s), as well as binding fragments, derivatives and variants thereof can be used in pharmaceutical and diagnostic compositions for IAPP and/or proIAPP targeted immunotherapy and diagnostics, respectively.
    Type: Application
    Filed: September 12, 2013
    Publication date: July 30, 2015
    Inventors: Jan Grimm, Fabrice Heitz, Feng Cheng, Ioana Combaluzier