Patents by Inventor Fabrice Rebeille

Fabrice Rebeille has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD FOR THE PRODUCTION OF TRIACYLGLYCERIDES AND FATTY ACIDS
    Publication number: 20210230650
    Abstract: The disclosure pertains to a method for the production of triacylglycerides (TAGs or Triacylglyerols) and fatty acids by the recombinant expression of a ?11 fatty acid desaturase in protists.
    Type: Application
    Filed: January 30, 2019
    Publication date: July 29, 2021
    Inventors: Alberto Amato, Younes Dellero, Juliette Jouhet, Eric Marechal, Fabrice Rebeille
  • Inhibitors of sterol metabolism for their use to accumulate triglycerides in microalgae, and methods thereof
    Patent number: 10844411
    Abstract: The invention relates to a method for accumulating triacylglycerols in microalgae by inhibiting the sterol metabolism, by incubating the microalgae with an inhibitor of sterol metabolism. The invention also relates to a method for producing fatty acids, biofuels, pharmaceutical or cosmetic compositions, and also food supplements, comprising a triacylglycerols accumulation step in microalgae according to the invention. Finally, the invention concerns the use of an inhibitor of sterol metabolism to accumulate triglycerides in microorganisms, and preferably microalgae.
    Type: Grant
    Filed: January 27, 2015
    Date of Patent: November 24, 2020
    Assignees: Commissariat A L'Energie Atomique Et Aux Energies Alternatives, Centre National De La Recherche Scientifique
    Inventors: Melissa Conte, Lina-Juana Dolch, Coline Mei, Caroline Barette, Dimitris Petroutsos, Denis Falconet, Juliette Jouhet, Fabrice Rebeille, Jean-Christophe Cintrat, Eric Marechal
  • Alga modified for increased tag production
    Patent number: 10724011
    Abstract: The present technology relates to a microalga that is genetically modified by inhibiting the activity of the enzyme ?0-elongase (?0-ELO), which uses palmitic acid, a saturated fatty acid, as substrate and is associated with the production of monogalactosyldiacylglycerol (MGDG). The present technology also relates to a process for culturing the microalga for increased production of triacylglycerols (TAGs) and recovery of the TAGs.
    Type: Grant
    Filed: June 27, 2017
    Date of Patent: July 28, 2020
    Assignees: FERMENTALG, COMMISSARIAT A L'ENERGIE ATOMIQUE ET AUX ENERGIES ALTERNATIVES
    Inventors: Lina Juana Dolch, Camille Rak, Fabrice Rebeille, Juliette Jouhet, Marina Leterrier, Eric Marechal
  • ALGA MODIFIED FOR INCREASED TAG PRODUCTION
    Publication number: 20190264183
    Abstract: The invention relates to a microalga which is genetically modified by inhibiting the ?0 elongase (?0-ELO) enzyme activity, using palmitic acid, a saturated fatty acid, as a substrate, and which is associated with the production of mono-galactosyl diacylglycerol (MGDG). The invention also relates to a method for cultivating said microalga for increased triacylglycerol (TAG) production and harvesting of said TAG.
    Type: Application
    Filed: June 27, 2017
    Publication date: August 29, 2019
    Inventors: Lina Juana DOLCH, Camille RAK, Fabrice REBEILLE, Juliette JOUHET, Marina LETERRIER, Eric MARECHAL
  • INHIBITORS OF STEROL METABOLISM FOR THEIR USE TO ACCUMULATE TRIGLYCERIDES IN MICROALGAE, AND METHODS THEREOF
    Publication number: 20160348138
    Abstract: The invention relates to a method for accumulating triacylglycerols in microalgae by inhibiting the sterol metabolism, N by incubating the microalgae with an inhibitor of sterol metabolism. The invention also relates to a method for producing fatty acids, biofuels, pharmaceutical or cosmetic compositions, and also food supplements, comprising a triacylglycerols accumulation step in microalgae according to the invention. Finally, the invention concerns the use of an inhibitor of sterol metabolism to accumulate triglycerides in microorganisms, and preferably microalgae.
    Type: Application
    Filed: January 27, 2015
    Publication date: December 1, 2016
    Inventors: Melissa Conte, Lina-Juana Dolch, Coline Mei, Caroline Barette, Dimitris Petroutsos, Denis Falconet, Juliette Jouhet, Fabrice Rebeille, Jean-Christophe Cintrat, Eric Marechal