Patents by Inventor Fabrizio Bianchi

Fabrizio Bianchi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • PROGNOSTIC METHOD FOR AGGRESSIVE LUNG ADENOCARCINOMAS
    Publication number: 20240368698
    Abstract: The present invention relates to methods based on miRNA biomarkers for the prognosis of aggressive lung adenocarcinoma (ADC) including early-stage (stage I) disease, preferably in fresh-frozen or in formalin-fixed, paraffin-embedded (FFPE) specimens. More in particular, the invention refers to the use of 7-miRNA, 14-miRNA or 19-miRNA prognostic signatures in a method for prognostic risk stratification of ADC, preferably for identify patients with aggressive early-stage lung adenocarcinoma (namely C1-ADC).
    Type: Application
    Filed: December 10, 2021
    Publication date: November 7, 2024
    Inventors: Fabrizio BIANCHI, Elisa DAMA, Valentina MELOCCHI
  • METHODS FOR LUNG CANCER DETECTION
    Publication number: 20170283883
    Abstract: The disclosure describes a method for diagnosing lung cancer in a subject by detecting in a biological sample obtained from that patient a miRNA signature, the presence of which provides an earlier indication of cancer than alternative art-recognized methods, including, but not limited to, low-dose computed tomography (LDCT).
    Type: Application
    Filed: September 9, 2015
    Publication date: October 5, 2017
    Inventors: Pier Paolo Di FIORE, Fabrizio BIANCHI, Francesco NICASSIO, Matteo Jacopo Luca Nicolo MARZI, Francesca MONTANI
  • Methods for Lung Cancer Detection
    Publication number: 20160068913
    Abstract: The disclosure describes a method for diagnosing lung cancer in a subject by detecting in a biological sample obtained from that patient a miRNA signature, the presence of which provides an earlier indication of cancer than alternative art-recognized methods, including, but not limited to, low-dose computed tomography (LDCT).
    Type: Application
    Filed: September 9, 2015
    Publication date: March 10, 2016
    Inventors: Pier Paolo Di Fiore, Fabrizio Bianchi, Francesco Nicassio, Matteo Jacopo Luca Nicolo Marzi, Francesca Montani
  • METHOD TO IDENTIFY ASYMPTOMATIC HIGH-RISK INDIVIDUALS WITH EARLY STAGE LUNG CANCER BY MEANS OF DETECTING miRNAs IN BIOLOGIC FLUIDS
    Publication number: 20150057159
    Abstract: A diagnostic and/or prognostic model of at least 5 serum miRNAs selected among a group of 34 miRNAs that identifies subjects with early stage lung cancer, namely non-small cell lung carcinomas (NSCLCs), in a population of asymptomatic high-risk individuals, with 80% accuracy. The model could also distinguish between benign and malignant lesions and is sensitive enough to capture the disease onset. In addition, the model could also diagnose or confirm a diagnosis of lung cancer in symptomatic patients, and monitor the lung tumor status after treatment with surgery and/or chemotherapy and/or radiotherapy in a subject with such lung cancer.
    Type: Application
    Filed: December 22, 2011
    Publication date: February 26, 2015
    Applicants: ISTITUTO EUROPEO DI ONCOLOGIA S.R.L., UNIVERSITA DEGLI STUDI DI MILANO, IFOM Fondazione Istituto FIRC di Oncologia Moleco lare
    Inventors: Pierpaolo Di Fiore, Fabrizio Bianchi, Matteo Jacopo Luca Nicolò Marzi, Francesco Nicassio
  • Cancer markers
    Patent number: 8747867
    Abstract: The invention relates to methods of diagnosis and prognosis of cancer, and in particular NSCLC, the methods comprising determining the expression level of one or more genes. In some embodiments the invention relates to prognosis of early stage NSCLC.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: June 10, 2014
    Assignee: IFOM Fondazione Instituto Firc Di Oncologia Molecolare
    Inventors: Pier Paolo Di Fiore, Francesco Nicassio, Fabrizio Bianchi
  • CANCER MARKERS
    Publication number: 20100152058
    Abstract: The invention relates to methods of diagnosis and prognosis of cancer, and in particular NSCLC, the methods comprising determining the expression level of one or more genes. In some embodiments the invention relates to prognosis of early stage NSCLC.
    Type: Application
    Filed: October 9, 2009
    Publication date: June 17, 2010
    Inventors: Pier Paolo Di Fiore, Francesco Nicassio, Fabrizio Bianchi
  • Cancer Markers
    Publication number: 20080188405
    Abstract: The invention related to methods of diagnosis and prognosis of cancer, the methods comprising determining the level of one or more gene products. In addition, the invention relates to modulators of the gene products for use in treatment of cancer. The genes include EIA-induced genes and Numb.
    Type: Application
    Filed: September 20, 2005
    Publication date: August 7, 2008
    Inventors: Pier Paolo Di Fiore, Salvatore Pece, Ian Marc Bonapace, Francesco Nicassio, Fabrizio Bianchi, Manuela Vecchi, Stefano Confalonieri