Patents by Inventor Fabrizio Caldera

Fabrizio Caldera has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240066130
    Abstract: The invention relates to oral administration of biological actives, in particular of insulin, comprising the use of a cross-linked starchy material as a delivery system.
    Type: Application
    Filed: October 26, 2023
    Publication date: February 29, 2024
    Inventors: Francesco TROTTA, Roberta Cavalli, Fabrizio Caldera, Monica Argenziano, Maria Tannous
  • Patent number: 11844838
    Abstract: The invention relates to oral administration of biological actives, in particular of insulin, comprising the use of a cross-linked starchy material as a delivery system.
    Type: Grant
    Filed: July 11, 2018
    Date of Patent: December 19, 2023
    Assignee: ROQUETTE FRERES
    Inventors: Francesco Trotta, Roberta Cavalli, Fabrizio Caldera, Monica Argenziano, Maria Tannous
  • Patent number: 11440975
    Abstract: The invention relates a process for preparing a cross-linked starch-based polymer comprising the following steps: 1) dissolving a starchy material in a suitable solvent to form a starchy material solution; and 2) adding a episulfide of formula (I), wherein R1, R2, R3 and R4 are independently selected from hydrogen and (C1-C3)alkyl in the starchy material solution in order to obtain the disulfide crosslinked starch-based polymer. In another aspect the invention concerns a disulfide-cross-linked starch-based polymer obtainable by the process of the invention, that is characterized by only disulfide bridges.
    Type: Grant
    Filed: April 19, 2019
    Date of Patent: September 13, 2022
    Assignee: ROQUETTE FRERES
    Inventors: Francesco Trotta, Fabrizio Caldera
  • Publication number: 20210238315
    Abstract: The invention relates a process for preparing a cross-linked starch-based polymer comprising the following steps: 1) dissolving a starchy material in a suitable solvent to form a starchy material solution; and 2) adding a episulfide of formula (I), wherein R1, R2, R3 and R4 are independently selected from hydrogen and (C1-C3)alkyl in the starchy material solution in order to obtain the disulfide crosslinked starch-based polymer. In another aspect the invention concerns a disulfide-cross-linked starch-based polymer obtainable by the process of the invention, that is characterized by only disulfide bridges.
    Type: Application
    Filed: April 19, 2019
    Publication date: August 5, 2021
    Inventors: Francesco TROTTA, Fabrizio CALDERA
  • Publication number: 20210085795
    Abstract: The invention relates to oral administration of biological actives, in particular of insulin, comprising the use of a cross-linked starchy material as a delivery system.
    Type: Application
    Filed: July 11, 2018
    Publication date: March 25, 2021
    Inventors: Francesco TROTTA, Roberta CAVALLI, Fabrizio CALDERA, Monica ARGENZIANO, Maria TANNOUS
  • Patent number: 9987614
    Abstract: The invention relates a process for preparing a microporous carbon material comprising the following steps: i) providing a cross-linked polymer obtainable by reacting either A1) a maltodextrin deriving from starch comprising amylose in the range from 25 to 50% expressed as dry weight relative to the dry weight of the starch or A2) a cyclodextrin with an organic aromatic dianhydride in a mass ratio of either maltodextrin or cyclodextrin with respect to the organic aromatic dianhydride in the range of 1:0.50 to 1:2, ii) pyrolyzing at a range from 700 to 900° C. with a heating ramp in the range from 5° C./min to 30° C./min in a inert gas flux; and iii) cooling the obtained residue. The microporous carbon material obtainable by the process of the invention consists of micropores having pore size distribution in the range from about 6 to about 16 ? and is used as absorber for liquids and gases.
    Type: Grant
    Filed: October 15, 2014
    Date of Patent: June 5, 2018
    Assignee: Roquette Italia S.P.A.
    Inventors: Francesco Trotta, Fabrizio Caldera, Marco Zanetti, Anastasia Anceschi, Giuliana Magnacca
  • Publication number: 20160271580
    Abstract: The invention relates a process for preparing a microporous carbon material comprising the following steps: i) providing a cross-linked polymer obtainable by reacting either A1) a maltodextrin deriving from starch comprising amylose in the range from 25 to 50% expressed as dry weight relative to the dry weight of the starch or A2) a cyclodextrin with an organic aromatic dianhydride in a mass ratio of either maltodextrin or cyclodextrin with respect to the organic aromatic dianhydride in the range of 1:0.50 to 1:2, ii) pyrolyzing at a range from 700 to 900° C. with a heating ramp in the range from 5° C./min to 30° C./min in a inert gas flux; and iii) cooling the obtained residue. The microporous carbon material obtainable by the process of the invention consists of micropores having pore size distribution in the range from about 6 to about 16 ? and is used as absorber for liquids and gases.
    Type: Application
    Filed: October 15, 2014
    Publication date: September 22, 2016
    Inventors: Francesco Trotta, Fabrizio Caldera, Marco Zanetti, Anastasia Anceschi, Giuliana Magnacca