Patents by Inventor Fabrizio Carta

Fabrizio Carta has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sulfonamide compounds for inhibition of metastatic tumor growth
    Patent number: 9962398
    Abstract: Therapeutic ureido-sulfonamide compositions having compounds with the formula R-Q-Ar—SO2NH2 are disclosed, which compounds selectively inhibit CAIX and CAXII, and which are effective to inhibit hypoxic tumor growth, suppress metastases, and impair and deplete cancer stem cells in mammals.
    Type: Grant
    Filed: September 20, 2016
    Date of Patent: May 8, 2018
    Assignee: Welichem Biotech Inc.
    Inventors: Claudiu Supuran, Shoukat Dedhar, Paul C. McDonald, Fabrizio Carta
  • NOVEL SULFONAMIDE COMPOUNDS FOR INHIBITION OF METASTATIC TUMOR GROWTH
    Publication number: 20170007627
    Abstract: Therapeutic ureido-sulfonamide compositions having compounds with the formula R-Q-Ar—SO2NH2 are disclosed, which compounds selectively inhibit CAIX and CAXII, and which are effective to inhibit hypoxic tumor growth, suppress metastases, and impair and deplete cancer stem cells in mammals.
    Type: Application
    Filed: September 20, 2016
    Publication date: January 12, 2017
    Inventors: Claudiu SUPURAN, Shoukat DEDHAR, Paul C. MCDONALD, Fabrizio CARTA
  • Sulfonamide compounds for inhibition of metastatic tumor growth
    Patent number: 9463171
    Abstract: Therapeutic ureido-sulfonamide compositions having compounds with the formula R-Q-Ar—SO2NH2 are disclosed, which compounds selectively inhibit CAIX and CAXII, and which are effective to inhibit hypoxic tumor growth, suppress metastases, and impair and deplete cancer stem cells in mammals.
    Type: Grant
    Filed: January 9, 2013
    Date of Patent: October 11, 2016
    Assignee: Welichem Biotech Inc.
    Inventors: Claudiu Supuran, Shoukat Dedhar, Paul C. McDonald, Fabrizio Carta
  • ASSEMBLY COMPRISING AN ABSORBER OF NEAR INFRARED (NIR) LIGHT COVALENTLY LINKED TO AN INHIBITOR OF CARBONIC ANHYDRASE
    Publication number: 20160015661
    Abstract: An assembly comprising an absorber of near infrared (NIR) light having an optical absorption cross section not lower than 100 nm2 covalently linked to an inhibitor of carbonic anhydrase (CA), process for its preparation and its use to hyperthermally target tumours or for treating other conditions in which the CA activity is involved is disclosed.
    Type: Application
    Filed: March 6, 2014
    Publication date: January 21, 2016
    Applicant: CONSIGLIO NAZIONALE DELLE RICERCHE
    Inventors: Roberto PINI, Fulvio RATTO, Francesca TATINI, Franco FUSI, Sonia CENTI, Andrea SCOZZAFAVA, Claudiu Trandafir SUPURAN, Fabrizio CARTA, Sergio CAPACCIOLI, Ewa Janina WITORT
  • CARBONIC ANHYDRASE INHIBITORS WITH ANTIMETASTATIC ACTIVITY
    Publication number: 20140148400
    Abstract: Derivatized coumarin-based pharmaceutical compositions and methods to use them are provided. The compositions are characterized in that they inhibit the activity of tumor-related CAIX and CAXII to a greater degree than they inhibit the activity of CAI and CAII. The compositions can be used to suppress tumor growth and/or suppress tumor metastases in a mammal.
    Type: Application
    Filed: November 12, 2013
    Publication date: May 29, 2014
    Applicants: METASIGNAL THERAPEUTICS INC., CNRS-DIRE, UNIVERSITE MONTPELLIER 2 SCIENCES ET TECHNIQUES
    Inventors: Claudiu Supuran, Shoukat Dedhar, Fabrizio Carta, Jean-Yves Winum, Paul C. McDonald