Patents by Inventor Fabrizio Rebasti

Fabrizio Rebasti has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of decahydro-2a,4a,6a,8a-tetraazacyclopent[fg]acenaphthylene and functionalized derivatives
    Patent number: 6897311
    Abstract: A process for the preparation of compound of formula (I A), decahydro-2a,4a,6a,8a-tetraazacyclopent[fg]accnaphthylene and the corresponding functionalized compounds of general formula (I), intermediates for the preparation of 1,4,7,10-tetraazacyclododecane (II A) and corresponding derivatives (II), by preparation of compounds of general formula (III) and subsequent reduction thereof.
    Type: Grant
    Filed: April 10, 2001
    Date of Patent: May 24, 2005
    Assignee: Bracco International BV
    Inventors: Maria Argese, Marino Brocchetta, Giuseppe Manfredi, Fabrizio Rebasti, Giorgio Ripa
  • Process for the preparation of decahydro-2a,4a,6a,8a-tetraazacyclopent[fg]acenaphthylene and functionalized derivatives
    Publication number: 20040014974
    Abstract: A process for the preparation of compound of formula (I A), decahydro-2a,4a,6a,8a-tetraazacyclopent[fg]accnaphthylene and the corresponding functionalized compounds of general formula (1), intermediates for the preparation of 1,4,7,10-tetraazacyclododecane (II A) and corresponding derivatives (II), by preparation of compounds of general formula (III) and subsequent reduction thereof.
    Type: Application
    Filed: November 25, 2002
    Publication date: January 22, 2004
    Inventors: Maria Argese, Marino Brocchetta, Giuseppe Manfredi, Fabrizio Rebasti, Giorgio Ripa
  • Process for the preparation of 1,4,7,10-tetraazacyclododecane
    Patent number: 6653470
    Abstract: 1,4,7,10-Tetraazacyclodecane, a precursor for the synthesis of macrocylic chelating agents for metal ions such as gadolinium, is prepared efficiently as a highly pure product on an industrial scale.
    Type: Grant
    Filed: October 11, 2001
    Date of Patent: November 25, 2003
    Assignee: Bracco International B.V.
    Inventors: Maria Argese, Giuseppe Manfredi, Fabrizio Rebasti, Giorgio Ripa
  • Diagnostic imaging contrast agent with improved in serum relaxivity
    Patent number: 6403055
    Abstract: Compounds of formula (I): are used as their paramagnetic chelates as contrast agents in magnetic resonance imaging. These compounds have high affinity to plasma proteins and exhibit extremely high values of relaxivity in serum and are thus useful as blood pool contrast agents.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: June 11, 2002
    Assignee: Dibra S.p.A.
    Inventors: Luisella Calabi, Alessandro Maiocchi, Marco Lolli, Fabrizio Rebasti