Patents by Inventor Fabrizio S. Chiacchia

Fabrizio S. Chiacchia has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
    Patent number: 8410109
    Abstract: The present invention relates to polyphenol-like compounds that are useful for inhibiting VCAM-1 expression, MCP-1 expression and/or SMC proliferation in a mammal. The disclosed compounds are useful for regulating markers of inflammatory conditions, including vascular inflammation, and for treatment and prevention of inflammatory and cardiovascular diseases and related disease states.
    Type: Grant
    Filed: July 28, 2006
    Date of Patent: April 2, 2013
    Assignee: Resverlogix Corp.
    Inventors: Norman C. W. Wong, Henrik C. Hansen, Fabrizio S. Chiacchia, Jan O. Johansson
  • Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
    Patent number: 8242144
    Abstract: The present disclosure provides non-naturally occurring polyphenol compounds that upregulate the expression of Apolipoprotein A-I (ApoA-I). The disclosed compositions and methods can be used for treatment and prevention of cardiovascular disease and related disease states, including cholesterol or lipid related disorders, such as, e.g., atherosclerosis.
    Type: Grant
    Filed: October 15, 2010
    Date of Patent: August 14, 2012
    Assignee: Resverlogix Corp.
    Inventors: Norman C. W. Wong, Joseph E. L. Tucker, Henrik C. Hansen, Fabrizio S. Chiacchia, David McCaffrey
  • Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases
    Patent number: 8242130
    Abstract: The present disclosure provides non-naturally occurring polyphenol compounds that upregulate the expression of Apolipoprotein A-I (ApoA-I). The disclosed compositions and methods can be used for treatment and prevention of cardiovascular disease and related disease states, including cholesterol or lipid related disorders, such as, e.g., atherosclerosis.
    Type: Grant
    Filed: February 11, 2009
    Date of Patent: August 14, 2012
    Assignee: Resverlogix Corp.
    Inventors: Norman C. W. Wong, Joseph E. L. Tucker, Henrik C. Hansen, Fabrizio S. Chiacchia, David McCaffrey
  • Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases
    Patent number: 8093273
    Abstract: The present disclosure provides non-naturally occurring polyphenol compounds that upregulate the expression of Apolipoprotein A-I (ApoA-I). The disclosed compositions and methods can be used for treatment and prevention of cardiovascular disease and related disease states, including cholesterol or lipid related disorders, such as, e.g., atherosclerosis.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: January 10, 2012
    Assignee: Resverlogix Corp.
    Inventors: Norman C. W. Wong, Joseph E. L. Tucker, Henrik C. Hansen, Fabrizio S. Chiacchia, David McCaffrey
  • Stilbenes and Chalcones for the Prevention and Treatment of Cardiovascular Diseases
    Publication number: 20110082176
    Abstract: The present disclosure provides non-naturally occurring polyphenol compounds that upregulate the expression of Apolipoprotein A-I (ApoA-I). The disclosed compositions and methods can be used for treatment and prevention of cardiovascular disease and related disease states, including cholesterol or lipid related disorders, such as, e.g., atherosclerosis.
    Type: Application
    Filed: October 15, 2010
    Publication date: April 7, 2011
    Inventors: Norman C.W. Wong, Joseph E.L. Tucker, Henrik C. Hansen, Fabrizio S. Chiacchia, David McCaffrey
  • Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
    Patent number: 7846915
    Abstract: The present disclosure provides non-naturally occurring polyphenol compounds that upregulate the expression of Apolipoprotein A-I (ApoA-I). The disclosed compositions and methods can be used for treatment and prevention of cardiovascular disease and related disease states, including cholesterol or lipid related disorders, such as, e.g., atherosclerosis.
    Type: Grant
    Filed: October 20, 2005
    Date of Patent: December 7, 2010
    Assignee: Resverlogix Corporation
    Inventors: Norman C. W. Wong, Joseph E. L. Tucker, Henrik C. Hansen, Fabrizio S. Chiacchia, David McCaffrey
  • FLAVANOIDS AND ISOFLAVANOIDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES
    Publication number: 20090259048
    Abstract: The present disclosure provides non-naturally occurring polyphenol compounds that upregulate the expression of Apolipoprotein A-I (ApoA-I). The disclosed compositions and methods can be used for treatment and prevention of cardiovascular disease and related disease states, including cholesterol or lipid related disorders, such as, e.g., atherosclerosis.
    Type: Application
    Filed: February 11, 2009
    Publication date: October 15, 2009
    Applicant: Resverlogix Corp.
    Inventors: Norman C.W. Wong, Joseph E.L. Tucker, Henrik C. Hansen, Fabrizio S. Chiacchia, David McCaffrey
  • Pharmaceutical Compositions for the Prevention and Treatment of Complex Diseases and Their Delivery by Insertable Medical Devices
    Publication number: 20090029987
    Abstract: The present invention relates to polyphenol-like compounds that are useful for inhibiting VCAM-1 expression, MCP-1 expression and/or SMC proliferation in a mammal. The disclosed compounds are useful for regulating markers of inflammatory conditions, including vascular inflammation, and for treatment and prevention of inflammatory and cardiovascular diseases and related disease states.
    Type: Application
    Filed: July 28, 2006
    Publication date: January 29, 2009
    Applicant: RESVERLOGIX CORP.
    Inventors: Norman C.W. Wong, Henrik C. Hansen, Fabrizio S. Chiacchia, Jan O. Johansson
  • COMPOUNDS FOR THE PREVENTION AND TREATMENT OF CARDIOVASCULAR DISEASES
    Publication number: 20080188467
    Abstract: The present disclosure relates to compounds, which are useful for regulating the expression of apolipoprotein A-I (ApoA-I), and their use for treatment and prevention of cardiovascular disease and related disease states, including cholesterol- or lipid-related disorders, such as, for example, atherosclerosis.
    Type: Application
    Filed: February 1, 2007
    Publication date: August 7, 2008
    Inventors: Norman C.W. Wong, Joseph E.L. Tucker, Henrik C. Hansen, Fabrizio S. Chiacchia, David McCaffrey