Patents by Inventor Fabrizio Samaritani

Fabrizio Samaritani has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Liquid growth hormone formulation and process of preparation thereof
    Publication number: 20060252682
    Abstract: The invention relates to a liquid formulation comprising a growth hormone or a, substance, which stimulates release or potentiates the activity of endogenous hGH; a polyethylene-polypropylene glycol; a citrate buffer and a stabilizer, and to a process of preparation thereof.
    Type: Application
    Filed: March 11, 2004
    Publication date: November 9, 2006
    Applicant: Ares Trading S.A.
    Inventors: Piergiorgio Donati, Fabrizio Samaritani
  • GRF-containing lyophilized pharmaceutical compositions
    Publication number: 20060160739
    Abstract: Human growth hormone factor (GFR) containing pharmaceutical compositions are described, and more precisely, lyophilized compositions of hGRF stabilized by means of saccharose.
    Type: Application
    Filed: March 1, 2006
    Publication date: July 20, 2006
    Inventors: Fabrizio Samaritani, Alessandra Del Rio
  • Liquid pharmaceutical formulations of fsh and lh together with a non-ionic surfactant
    Publication number: 20060147480
    Abstract: The invention relates to the field of pharmaceutical formulations of follicle-stimulating hormone (FSH), luteinising hormone (LH), and mixtures of FSH and luteinising hormone (LH), and to methods of producing such formulations. The invention provides a liquid or freeze-dried formulation of FSH, or LH, or FSH and LH comprising a surfactant selected from Pluronic® F77, Pluronic F87, Pluronic F88 and Pluronic F68.
    Type: Application
    Filed: April 2, 2004
    Publication date: July 6, 2006
    Applicant: ARES TRADING S.A.
    Inventors: Fabrizio Samaritani, Piergiorgio Donati
  • IFN-? liquid formulations
    Patent number: 6852314
    Abstract: Interferon-? liquid formulations stabilized with a polyol, a non-reducing sugar or an amino acid. In particular, the formulations are stabilized with a polyol, such as mannitol. The formulations, preferably, furthermore comprise a buffer, such as acetate buffer, at a pH comprised between 3.0 and 4.0 and human albumin at a minimum quantity. The interferon-? is preferably recombinant.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: February 8, 2005
    Assignee: Applied Research Systems ARS Holding N.V.
    Inventors: Fabrizio Samaritani, Patrizia Natale
  • IFN-beta liquid formulations
    Publication number: 20040265270
    Abstract: Interferon-beta liquid formulations stabilized with a polyol, a non-reducing sugar or a amino acid. In particular, the formulations are stabilized with a polyol, such as mannitol. The formulations, preferably, furthermore comprise a buffer, such as acetate buffer, at a pH comprised between 3.0 and 4.0 and human albumin at a minimum quantity. The interferon-beta is preferably recombinant.
    Type: Application
    Filed: July 16, 2004
    Publication date: December 30, 2004
    Applicant: Applied Research Systems ARS Holding N.V.
    Inventors: Fabrizio Samaritani, Patrizia Natale
  • HCG liquid formulations
    Patent number: 6706681
    Abstract: The invention refers to liquid pharmaceutical compositions containing hCG stabilised with a polyalcohol or a non-reducing sugar. Preferably, the compositions are stabilised with mannitol. In the preferred embodiments such compositions are aqueous solutions in a phosphate buffer at pH 7. Such compositions are ready to be injected and, therefore, the step of reconstitution of the lyophilised powder is avoided, thus simplifying the way of use.
    Type: Grant
    Filed: November 21, 1997
    Date of Patent: March 16, 2004
    Assignee: Applied Research System ARS Holding N.V.
    Inventors: Fabrizio Samaritani, Patrizia Natale
  • hGH containing pharmaceutical compositions
    Patent number: 5898030
    Abstract: Pharmaceutical compositions containing hGH stabilized by means of saccharose. The formulation is particularly suitable for stabilizing a lyophilisate of recombinant hGH.
    Type: Grant
    Filed: December 17, 1996
    Date of Patent: April 27, 1999
    Assignee: Applied Research Systems Ars Holding N.V
    Inventor: Fabrizio Samaritani
  • Gonadotropin containing pharmaceutical compositions with sucrose stabilizer
    Patent number: 5650390
    Abstract: Pharmaceutical compositions containing FSH, LH or hCG stabilized by means of a combination of sucrose and glycine. The formulation is particularly suitable for stabilizing a lyophilisate of recombinant gonadotropins.
    Type: Grant
    Filed: July 28, 1994
    Date of Patent: July 22, 1997
    Assignee: Applied Research Systems ARS Holding N. V.
    Inventors: Fabrizio Samaritani, Patrizia Natale
  • Pharmaceutical compositions containing IL-6
    Patent number: 5635176
    Abstract: Pharmaceutical compositions based on Interleukin-6 (IL-6) stabilized with non reducing sugars, such as sucrose and trehalose. The compositions may also contain an amino acid or human albumin as an excipient. The formulation is particularly suitable for the stabilization of recombinant IL-6 freeze-dried powder.
    Type: Grant
    Filed: November 10, 1994
    Date of Patent: June 3, 1997
    Assignee: Applied Research Systems Ars Holding N.V.
    Inventors: Fabrizio Samaritani, Filippo Rendina