Patents by Inventor Facheng MA

Facheng MA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • NEW CRYSTAL FORM OF NITROGEN-CONTAINING TRICYCLIC COMPOUND AND USE THEREOF
    Publication number: 20250268871
    Abstract: A new crystal form of compound 2-((5-cyclopropyl-3-(2,6-dichlorophenyl) isoxazol-4-yl) methoxy)-10H-spiro[benzo[6,7]oxepino[3,2-b]pyridine-11,1?-cyclopropane]-7-carboxylic acid. The new crystal form is crystal form J. Further disclosed are a pharmaceutical composition containing the crystal form J, and the use of the crystal form J or the pharmaceutical composition in the preparation of a drug for preventing, treating or relieving an FXR-mediated disease of a patient.
    Type: Application
    Filed: October 14, 2022
    Publication date: August 28, 2025
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Yuefeng SHAN, Liang CHEN, Xinye YANG, Jihua LIN, Facheng MA, Xiaozhou CHEN, Xiaojun WANG
  • PREPARATION METHOD FOR PYRROLE AMIDE COMPOUND
    Publication number: 20240239746
    Abstract: A preparation method for a pyrrole amide compound, as shown in formula (II). The preparation method includes: reacting a compound of formula (III) with a compound of formula (IV) in the presence of a palladium catalyst and a ligand, wherein X is Br or I; R is H, D, F, Cl, Br, C1-4 alkyl, C1-4 alkoxy, C1-4 haloalkyl or C1-4 haloalkoxy; and PG1 is benzyl or substituted benzyl.
    Type: Application
    Filed: April 19, 2022
    Publication date: July 18, 2024
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Jiancheng WANG, Yingxun ZHANG, Chuanwen YANG, Qiao ZONG, Facheng MA, Xiaohong DING, Xiaojun WANG
  • Carboxy substituted (hetero) aromatic ring derivatives and preparation method and uses thereof
    Patent number: 10266496
    Abstract: Carboxy-substituted (hetero)aryl derivatives, pharmaceutical compositions comprising these compounds, and methods of preparing such compounds and compositions are provided. The compounds or compositions are useful in inhibiting xanthine oxidase and urate anion transporter 1, and also can be used in the treatment or prevention of diseases associated with high blood uric acid level in mammals, especially humans.
    Type: Grant
    Filed: August 31, 2016
    Date of Patent: April 23, 2019
    Assignee: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Xinye Yang, Changwei Huang, Facheng Ma, Ji Zhang, Xiaojun Wang, Yingjun Zhang
  • CARBOXY SUBSTITUTED (HETERO) AROMATIC RING DERIVATIVES AND PREPARATION METHOD AND USES THEREOF
    Publication number: 20180230102
    Abstract: Carboxy-substituted (hetero)aryl derivatives, pharmaceutical compositions comprising these compounds, and methods of preparing such compounds and compositions are provided. The compounds or compositions are useful in inhibiting xanthine oxidase and urate anion transporter 1, and also can be used in the treatment or prevention of diseases associated with high blood uric acid level in mammals, especially humans.
    Type: Application
    Filed: August 31, 2016
    Publication date: August 16, 2018
    Applicant: SUNSHINE LAKE PHARMA CO., LTD.
    Inventors: Xinye YANG, Changwei HUANG, Facheng MA, Ji ZHANG, Xiaojun WANG, Yingjun ZHANG