Patents by Inventor Fahima KAUSAR

Fahima KAUSAR has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CHIMERIC NKG2D PROTEIN
    Publication number: 20230257443
    Abstract: This invention relates to an immunoresponsive cell comprising a chimeric NKG2D protein. The immunoresponsive cell is a T-cell, natural killer (NK) cell, macrophage or neutrophil and the chimeric NKG2D protein comprises a human NKG2D extracellular domain or a variant thereof, and a murine NKG2D transmembrane domain or a variant thereof. The disclosure also relates to isolated polynucleotide(s) encoding the chimeric NKG2D protein and the use of the immunoresponsive cells or isolated polynucleotides in therapy or the treatment of cancer.
    Type: Application
    Filed: May 21, 2021
    Publication date: August 17, 2023
    Inventors: John Maher, David Marc Davies, Fahima Kausar, Daniel Larcombe-Young
  • MUC1 PARALLEL CAR (pCAR) THERAPEUTIC AGENTS
    Publication number: 20220152103
    Abstract: Provided herein are immunoresponsive cells expressing a MUC1 targeting pCAR comprising a second generation chimeric antigen receptor (CAR) and a chimeric co-stimulatory receptor (CCR). Also provided herein are methods of preparing the immunoresponsive cells and methods of directing T cell mediated immune response using the immunoresponsive cells.
    Type: Application
    Filed: March 11, 2020
    Publication date: May 19, 2022
    Inventors: John MAHER, Lynsey WHILDING, Fahima KAUSAR, Leena HALIM, Tamara MULIADITAN, Maya GLOVER