Abstract: The present disclosure relates to the technical field of wheat planting, and in particular to a uniform monoseeding and cultivation method of winter wheat in Huang-huai-hai region. The cultivation method includes seedbed finishing and precision seeding; after seedbed finishing during winter wheat seeding creates excellent seedbed conditions, precision monoseeding of winter wheat is implemented by a seeder according to precise agronomic index requirements including plant spacing, row spacing, seeding depth, and seeding rate, concurrently achieving the objectives of consistent covering depth and deep placement of bottom fertilizer. The cultivation method can make the most of light, heat, water, and fertilizer resources, and precisely optimize the plant spacing, row spacing, and seeding depth during seeding to integrate mechanized seeding management of winter wheat in Huang-huai-hai region, achieving objectives of building excellent crop community and increasing yield and efficiency.