Abstract: An imaging system (1) is provided, comprising: an optical channel (2) configured to transfer light, a first sensor (10) configured to generate first image data by imaging an object (3) along a first optical path (11), and a second sensor (20) configured to generate second image data by imaging the object (3) along a second optical path (21). The first sensor (10) and the second sensor (20) are focus shifted. Further, the first optical path (11) and the second optical path (21) are guided at least partly through the optical channel (3).

Abstract: Devices and their uses for medical imaging in particular intra-operative imaging of tissue of a patient's body. The device comprises the illumination unit, the imaging unit, the processing unit and the display unit. The imaging unit captures fluorescent images (I_fluo) and live images (I_live) of the same scenery. In the processing unit, the fluorescent images (I_fluo) are processed by using the detected motion between the tissue and the imaging unit based on the detected motion. The filtered fluorescent images (I_filt) are non-linearly mapped into the live images (I_live) in order to improve the visibility of fluorophores in the tissue resulting in an overlay image (I_over) that comprises details of the live images (I_live) on the one hand and details of the fluorescent images (I_fluo) on the other hand.

Abstract: A method and device for medical imaging, in particular intra-operative imaging of a patient's body are disclosed. Fluorescence and live images are acquired by an imaging unit. A processing unit adapts one or more image capturing or processing parameters if the images are acquired in a static motion state. This reduces noise in the fluorescence images so the processing unit can detect a region of interest in the fluorescence images. The processing unit maps the region of interest into the live images. If the images are acquired in a moving motion state, the region of interest may be tracked by the processing unit and mapped back into the fluorescence images. In the moving state, the processing unit is configured to apply a spatially selective noise filter which distinguishes between the region of interest and the remaining region enhancing the quality of the fluorescence images without erasing details with noise filtering.

Abstract: An endoscope (1) is provided. The endoscope (1) comprises a fixed coupling member (2), and a rotatable shaft member (3) including a shaft (4) having a shaft axis (C) extending in an axial direction (d1), wherein the shaft (4) has a tip end (5) and a mounting end (6), wherein the shaft (4) is configured to transmit light from the mounting end (6) to the tip end (5) and to transmit image information from the tip end (5) to the mounting end (6). The coupling member (2) and the shaft member (3) are connected to each other such that the shaft member (3) is unlimitedly rotatable by 360° or more about the shaft axis (C) relative to the coupling member (2). Further, the shaft member (3) has a receiver (7) configured to receive energy.

Abstract: The disclosed system uses a body shape capturing device for acquiring a patient's body shape and a 3D shape generating device for additively manufacturing a patient receiving device that is at least partially adapted to the patient's body shape or at least partially deviates from the patient's body shape bringing the patient's body into a desired shape so that the outer shape of the patient's body during surgery is identical to the outer shape of the body during shape capturing. The patient receiving device comprises at least one tracker element that is detectable by a detection system. The detection system captures data indicating the at least one tracker element's position and/or orientation during surgery enabling, particularly for surgical operations on or in soft tissues with high flexibly and with no specific natural or artificial landmarks, the surgeon to orientate/navigate in live images from the surgical site.

Abstract: Augmented reality applications require precise camera calibration to reduce the overall target registration errors. The camera calibration determines the mathematical model of the camera in order to determine how the physical world space is mapped to the camera image space and thus is highly dependent on the optics of the camera. The camera calibration algorithm normally assumes that the optics of the camera is rigidly fixed, which in fact is not at least for tilted laparoscopic cameras as illustrated in FIGS. 6 to 8. Furthermore, any mechanical play between elements of the objective and the image converter will render the optics variable. According to the invention markers to will be placed within the field of view of the laparoscopic camera, which allows for determination of rotation of the optical part and mechanical misalignment without the necessity or providing any additional sensor.

Abstract: Embodiments of the invention provide systems and methods for providing augmented reality to a surgeon with the steps of acquiring at least one preoperative medical scan image of a region of interest in which the surgery is to be performed and introducing a fiducial device non-invasively or minimal invasively into a body lumen present in the region of interest of a patient. The fiducial device will be in particular introduced into a lumen, which can be clearly identified in the medical scan image. The fiducial device is adapted to emit infrared light either by using infrared light source or by using fluorescent material placed in or in the fiducial device ad to be excited by illumination light or exciting light.

Abstract: The disclosed system uses medical imaging and live imaging on a patient’s non-rigid tissue structures and increases preciseness and reliability by shaping the patient’s body during surgery so that the outer shape of the patient’s body during surgery is identical to the outer shape of the body during imaging. The processing unit will precisely overlay a scan image (or an image or a graphical representation derived from several scan images) and a live image acquired during surgery for enhancing a surgeon’s understanding and orientation during surgery.