Abstract: Described herein are apparatuses and methods for conditioning particles. In some embodiments, the apparatuses and methods are configured for first-in-first-out transit of particles through a chamber containing a conditioning fluid.

Abstract: An injection device for use with a pre-filled syringe. The device features a track and track follower engagement which facilitates locking a protective needle guard over the tip of the needle at the conclusion of the injection. The device further includes a tamper evidence overcap which, once removed from the device cannot be readily reinstalled. The injection device features a tubular handle which is grasped by the hand and moved towards the injection site to administer the injection. The device is suitable for self-administration of injections. Use of the device is not technique dependent. Its design, including tubular handle which is grasped in one hand, is easy to use even by the elderly and persons with limited dexterity.