Abstract: A method performed by a first network node for selecting a secondary cell for a first wireless device is provided. The first network node configures the first wireless device with a first threshold value relating to a signal quality for determining whether any secondary cell candidate(s) shall be reported to the first network node. The first network node receives a first report comprising a signal quality for secondary cell candidate whose measured signal quality meets the first threshold value. The first network node selects a first secondary cell candidate. The first network node instructs the first wireless device to attach to the first secondary cell candidate. The first network node detects that the first wireless device has failed a first series of random access attempts to the first secondary cell candidate. The first network node configures the first wireless device with a better second threshold value.

Abstract: Disclosed herein are methods for selectively treating acne vulgaris of the face and/or trunk in a subject, pharmaceutical compositions for use in the treatment of acne vulgaris of the face and/or trunk in a subject, uses of trifarotene or an equivalent thereof in the manufacture of a medicament for the treatment of acne vulgaris of the face and/or trunk in a subject.