Abstract: The field of the invention relates generally to devices and methods for controlling the temperature of a human or non-human body. More specifically, the field of the invention may relate to wearable devices, which may be worn by a subject, which human or non-human, wherein the wearable device is in thermal communication with a portion of the subject's body containing brown adipose tissue and wherein the wearable device comprises a means for providing a constant or near constant temperature to the subject's body and therefore controls the temperature of the subject's body, by using a phase change material. The phase material transitions state at a predetermined temperature which may be higher or lower than the subject's exterior body temperature. The device and method are usable to control temperature-related effects of menopause, post menopause and drug induced thermoregulatory symptoms such as night sweats, hot flashes and sleep disturbance.

Abstract: In accordance with one embodiment of the present invention, the invention comprises a pliable enclosure containing a Phase Change Material (PCM) that maintains a nearly constant predetermined temperature while transmitting heat during phase change. The predetermined temperature is maintained which the PCM absorbs heat from the body of the patient, thus maintain the patient's body temperature at a nearly constant predetermined temperature for as long as the PCM material is transitioning phase. The pliable enclosure, which in an embodiment forms an enclosed volume, may be comprised of a shell which contains the PCM. The shell may be fabricated from polyethylene, polyurethane, or any other pliable material and may further comprise graphene covering on at least one of its surfaces to provide a tough exterior that is resistant to puncture by, for example, hypodermic needles, suture needles, scalpels, or other sharp instruments.