Abstract: A material is provided for contact lens including a first siloxane macromer represented by the following formula (I): wherein R1, R2 and R3 are independently C1-C12 hydroxyl group, C1-C12 alkyl groups or C1-C12 siloxane group; R4 is C1-C6 alkylene group or C1-C6 alkylene substituted with ether group; R5 is —H, —CH3, —CH(CH3)2, —CH(CH3)CH2(CH3), —CH2CH(CH3)2, —CH2C6H5, —CH2OH, —CH(OH)CH3, —CH2CONH2 or —CH2CH2CONH2: R6 is —NHCONH—, —NHCO—, —R8NHCONH— or —R8NHCO—, wherein R8 is —O—, —O(CH2)n— or —(CH2)n— and n is an integer of 1-10; R7 is hydrogen or methyl; and m is an integer of 10-100.

Abstract: The method for manufacturing contact lenses includes the following steps. First, a first siloxane macromer, a second siloxane macromer, at least one hydrophilic monomer, an initiator and a solvent are mixed to form a mixture. Then the mixture is injected into a mold of contact lens and conducted by a thermal treatment or a UV irradiating treatment to form contact lenses. The number average molecular weight of the first siloxane macromer represented by the following formula (I), is 1,000 to 10,000 and the first siloxane macromer has a cross-linking function. The second siloxane macromer is selected from the group consisting of a siloxane macromer represented by the following formula (II) and a siloxane macromer represented by the following formula (III). Wherein in formula (II), p is an integer of 4 to 80, and in formula (III), q is an integer of 4 to 80 and r is an integer of 3 to 40.

Abstract: A polymerizable yellow dye which is used to block or lower the intensity of blue light transmitted through ophthalmic lenses and is represented by the following formula (I): wherein R1 is hydrogen or —NHCOCH3; R2 is hydrogen or C1-C3 alkyl groups; R3 and R4 are independently hydrogen or —OCO—R5, wherein R5 is isopropenyl group or a substituted isopropenyl group represented as —R6—(R7O)n—COC(CH3)CH2, R6 is NH or R7 is C1-C5 alkylene groups and n is an integer of 1-40.

Abstract: The invention provides a fluoro-containing ether monomer for fabricating contact lenses represented by following formula (I): In formula (I), R10 is fluoroalkyl group (CxFyHz, wherein x is an integer of 2-20, y is an integer of 5-30, and y+z=2x?1), R11 is oxygen, nitrogen or sulfur; R12 is C1-C3 alkylene; n is an integer of 3-40.

Abstract: The invention provides a fluoro-containing ether monomer for fabricating contact lenses represented by following formula (I): In formula (I), R10 is fluoroalkyl group (CxFyHz, wherein x is an integer of 2-20, y is an integer of 5-30, and y+z=2x+1), R11 is oxygen, nitrogen or sulfur; R12 is C1-C3 alkylene; n is an integer of 3-40.

Abstract: The method for manufacturing contact lenses includes the following steps. First, a first siloxane macromer, a second siloxane macromer, at least one hydrophilic monomer, an initiator and a solvent are mixed to form a mixture. Then the mixture is injected into a mold of contact lens and conducted by a thermal treatment or a UV irradiating treatment to form contact lenses. The number average molecular weight of the first siloxane macromer represented by the following formula (I), is 1,000 to 10,000 and the first siloxane macromer has a cross-linking function. The second siloxane macromer is selected from the group consisting of a siloxane macromer represented by the following formula (II) and a siloxane macromer represented by the following formula (III). Wherein in formula (II), p is an integer of 4 to 80, and in formula (III), q is an integer of 4 to 80 and r is an integer of 3 to 40.

Abstract: The invention provides a material for contact lenses, including a first siloxane macromer with the number average molecular weight of about 1,000 to 10,000, wherein the first siloxane macromer has a crosslinking function and is represented by the following formula (I): a second siloxane macromer is selected from the group consisting of a siloxane macromer represented by the following formula (II) and a siloxane macromer represented by the following formula (III): at least one hydrophilic monomer; and an initiator.

Abstract: A polymerizable yellow dye which is used to block or lower the intensity of blue light transmitted through ophthalmic lenses and is represented by the following formula (I): wherein R1 is hydrogen or —NHCOCH3; R2 is hydrogen or C1-C3 alkyl groups; R3 and R4 are independently hydrogen or —OCO—R5, wherein R5 is isopropenyl group or a substituted isopropenyl group represented as —R6—(R7O)n—COC(CH3)CH2, R6 is NH or R7 is C1-C5 alkylene groups and n is an integer of 1-40.

Abstract: The invention provides a fluoro-containing ether monomer for fabricating contact lenses represented by following formula (I): In formula (I), R10 is fluoroalkyl group (CxFyHz, wherein x is an integer of 2-20, y to is an integer of 5-30, and y+z=2x+1), R11 is oxygen, nitrogen or sulfur; R12 is C1-C3 alkylene; n is an integer of 3-40.

Abstract: The invention provides a material for contact lenses, including a first siloxane macromer with the number average molecular weight of about 1,000 to 10,000, wherein the first siloxane macromer has a crosslinking function and is represented by the following formula (I): formula (I); a second siloxane macromer is selected from the group consisting of a siloxane macromer represented by the following formula (II) and a siloxane macromer represented by the following formula (III): at least one hydrophilic monomer; and an initiator.

Abstract: A material is provided for contact lens including a first siloxane macromer represented by the following formula (I): wherein R1, R2 and R3 are independently C1-C12 hydroxyl group, C1-C12 alkyl groups or C1-C12 siloxane group; R4 is C1-C6 alkylene group or C1-C6 alkylene substituted with ether group; R5 is —H, —CH3, —CH(CH3)2, —CH(CH3)CH2(CH3), —CH2CH(CH3)2, —CH2C6H5, —CH2OH, —CH(OH)CH3, —CH2CONH2 or —CH2CH2CONH2: R6 is —NHCONH—, —NHCO—, —R8NHCONH— or —R8NHCO—, wherein R8 is —O—, —O(CH2)n— or —(CH2)n— and n is an integer of 1-10; R7 is hydrogen or methyl; and m is an integer of 10-100.

Abstract: A composition is provided for manufacturing contact lenses including a siloxane macromer represented by the following formula (I): wherein R1, R2 and R3 are independently C1-C4 alkyl groups, R4 is C1-C6 alkyl group, R5 is a residue obtained by removing NCO group from an aliphatic or aromatic diisocyanate, R6 and R7 are independently alkylene groups, and n is an integer of about 4-80, m is an integer of about 3-40; a crosslinking agent or a siloxane macromer represented by the following formula (II), wherein p is an integer of 4-80 and q is an integer of 3-40: and an initiator.

Abstract: A protein carrier containing an antigen presenting cell binding domain and a cysteine-rich domain. Also described herein is an immunoconjugate containing the protein carrier with an antigen conjugated to multiple cysteine residues in the cysteine-rich domain, and an immune composition containing the immunoconjugate and an adjuvant, as well as their uses in eliciting immune responses.

Abstract: A protein carrier containing an antigen presenting cell binding domain and a cysteine-rich domain. Also described herein is an immunoconjugate containing the protein carrier with an antigen conjugated to multiple cysteine residues in the cysteine-rich domain, and an immune composition containing the immunoconjugate and an adjuvant, as well as their uses in eliciting immune responses.