Patents by Inventor Fan Jaslyn Fu

Fan Jaslyn Fu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biocatalysts and methods for the synthesis of armodafinil
    Patent number: 9267159
    Abstract: The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods of using the polypeptides. The non-naturally occurring polypeptides of the present invention are effective in carrying out biocatalytic conversion of the (i) 2-(benzhydrylsulfinyl)acetamide to (?)-2-[(R)-(diphenyl-methyl)sulfinyl]acetamide (armodafinil), or (ii) benzhydryl-thioacetic acid to (R)-2-(benzhydrylsulfinyl)acetic acid, which is a pivotal intermediate in the synthesis of armodafinil, in enantiomeric excess.
    Type: Grant
    Filed: December 7, 2011
    Date of Patent: February 23, 2016
    Assignee: CODEXIS, INC.
    Inventors: Ee Lui Ang, Oscar Alvizo, Behnaz Behrouzian, Michael Clay, Steven Collier, Ellen Eberhard, Fan Jaslyn Fu, Shiwei Song, Derek Smith, Magnus Widegren, Robert Wilson, Junye Xu, Jun Zhu
  • BIOCATALYSTS AND METHODS FOR THE SYNTHESIS OF ARMODAFINIL
    Publication number: 20130260426
    Abstract: The present invention relates to non-naturally occurring polypeptides useful for preparing armodafinil, polynucleotides encoding the polypeptides, and methods of using the polypeptides. The non-naturally occurring polypeptides of the present invention are effective in carrying out biocatalytic conversion of the (i) 2-(benzhydrylsulfinyl)acetamide to (?)-2-[(R)-(diphenyl-methyl)sulfinyl]acetamide (armodafinil), or (ii) benzhydryl-thioacetic acid to (R)-2-(benzhydrylsulfinyl)acetic acid, which is a pivotal intermediate in the synthesis of armodafinil, in enantiomeric excess.
    Type: Application
    Filed: December 7, 2011
    Publication date: October 3, 2013
    Inventors: Ee Lui Ang, Oscar Alvizo, Behnaz Behrouzian, Michael Clay, Steven Collier, Ellen Eberhard, Fan Jaslyn Fu, Shiwei Song, Derek Smith, Magnus Widegren, Robert Wilson, Junye Xu, Jun Zhu