Patents by Inventor Fan Zhang

Fan Zhang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10611805
    Abstract: The disclosure provides modified biotin-binding proteins which can be expressed in soluble form in high yield in bacteria. Also provided are fusion proteins comprising the modified biotin-binding protein and an antigen. The disclosure further provides non-hemolytic variants of alpha-hemolysin from S. aureus and fusion protein comprising non-hemolytic variant of alpha-hemolysin and a biotin-binding domains. Immunogenic compositions comprising the proteins are also disclosed and use of such immunogenic compositions for inducing an immune response or for vaccinating a subject are also disclosed.
    Type: Grant
    Filed: May 30, 2018
    Date of Patent: April 7, 2020
    Assignee: CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Richard Malley, Yingjie Lu, Fan Zhang
  • Publication number: 20200104752
    Abstract: Systems and methods for ticket classification and response include labeling tickets with a ticket classifier that assigns a ticket label and an associated confidence score to each ticket. Tickets are clustered according to semantic similarity to form ticket clusters. A template associated with each ticket cluster is determined. Templates and the respective ticket clusters are clustered according to semantic similarity to form one or more ticket super-clusters. Tickets that have below-threshold confidence scores are labeled according to the one or more ticket super-clusters. The tickets are automatically responded to.
    Type: Application
    Filed: October 1, 2018
    Publication date: April 2, 2020
    Inventors: Fan Jing Meng, Lin Yang, Xiao Zhang, Shi Lei Zhang, Jing Min Xu, Naga A. Ayachitula, Zhuo Su
  • Publication number: 20200099579
    Abstract: A service deployment method and a network functions acceleration platform are provided. The method includes: when an FPGA is powered on, loading, by the FPGA, an FPGA framework file, so that the FPGA includes M partial reconfigurable PR areas, a configuration module, and a data flow forwarding module; when receiving a service configuration instruction, generating, by a physical machine, a VM, and selecting at least one PR area from the M PR areas to establish a correspondence with the VM; performing, by a configuration module, service resource configuration on the selected PR area according to a PR configuration resource, so that the selected PR area has a service processing capability; adding, by the configuration module, a forwarding entry corresponding to the PR area in a forwarding flow table, so that the data flow forwarding module forwards a received network packet to the corresponding PR area.
    Type: Application
    Filed: November 26, 2019
    Publication date: March 26, 2020
    Inventors: Yuming XIE, Liang ZHANG, Jun WU, Fan YANG
  • Publication number: 20200097883
    Abstract: Methods and systems for ticket classification and response include clustering tickets according to semantic similarity to form ticket clusters. A template associated with each ticket cluster is determined that includes an invariant portion and a variable portion. A new ticket sub-class, based on the variable portion of the template, is determined that represents a specific sub-type of an existing class. A ticket taxonomy is updated to include the new ticket sub-class. The tickets are labeled according to the updated ticket taxonomy. The tickets are automatically responded to.
    Type: Application
    Filed: September 26, 2018
    Publication date: March 26, 2020
    Inventors: Fan Jing Meng, Xiao Zhang, Peng Fei Chen, Lin Yang, Jing Min Xu, Shi Lei Zhang, Naga A. Ayachitula, Zhuo Su, Rohit Khandekar
  • Patent number: 10601546
    Abstract: A dynamic interleaver performs a read operation to identify bit lines with high failures, and form groups of data bits for parity bits computation, such that each group includes at most one data bit from the bit lines with high failures. Thus, the interleave selects the bit lines with high failures based on a most recent read test, and can be adjusted according to the conditions of the storage device.
    Type: Grant
    Filed: August 10, 2018
    Date of Patent: March 24, 2020
    Assignee: SK Hynix Inc.
    Inventors: Naveen Kumar, Aman Bhatia, Yu Cai, Chenrong Xiong, Fan Zhang, Xuanxuan Lu
  • Publication number: 20200087361
    Abstract: Technologies for the prevention and/or treatment of pneumococcal infections.
    Type: Application
    Filed: September 12, 2019
    Publication date: March 19, 2020
    Applicant: THE CHILDREN'S MEDICAL CENTER CORPORATION
    Inventors: Richard Malley, Yingjie Lu, Fan ZHANG
  • Publication number: 20200089799
    Abstract: Embodiments relate to cube construction. According to a method, a plurality of valid history queries that request to retrieve a cube comprising a first number of cuboids in an On-Line Analytical Processing (OLAP) system are collected. A plurality of dimension combinations is acquired from the plurality of valid history queries. A query frequency of each cuboid of a second number of cuboids with the plurality of dimension combinations is determined, the second number of cuboids being a subset of the first number of cuboids. A cuboid construction sequence for the second number of cuboids is determined based on the query frequency. The cube is constructed based on the cuboid construction sequence.
    Type: Application
    Filed: September 18, 2018
    Publication date: March 19, 2020
    Inventors: Jun Wei Zhang, Tao Xie, Wei Xu, Shan Fan
  • Publication number: 20200091020
    Abstract: A semiconductor interconnect structure including a conductive layer, a plurality of interconnect vias and a pad is presented. The interconnect vias are formed over the conductive layer and the pad having a substantially flat surface is formed over the plurality of interconnect vias. The conductive layer may be a conductive line and/or a conductive plate connected to a conductive line.
    Type: Application
    Filed: September 13, 2018
    Publication date: March 19, 2020
    Inventors: WANBING YI, LAIQIANG LUO, XINGYU CHEN, FAN ZHANG, JUAN BOON TAN
  • Publication number: 20200090731
    Abstract: Systems, memory controllers, decoders and methods perform decoding by exploiting differences among word lines for which soft decoding fails (failed word lines). Such decoding generates extrinsic information for codewords of failed word lines based on the soft decoding. The soft information obtained during the soft decoding is updated based on the extrinsic information, and the updated soft information is propagated across failed word lines. Low-density parity-check (LDDC) decoding of codewords of failed word lines is performed with the updated soft information.
    Type: Application
    Filed: September 18, 2019
    Publication date: March 19, 2020
    Inventors: Naveen KUMAR, Yu CAI, Fan ZHANG
  • Patent number: 10588903
    Abstract: Compositions and methods are described in which the topical application of a toll-like receptor 7 agonist or a toll-like receptor 9 agonist at or near a subdermal vaccination site provides an enhanced response to the vaccination. The enhanced response can be an elevated antibody titer relative to an untreated but vaccinated subject, and/or development of cross-species immunity to species not present in the vaccinating composition.
    Type: Grant
    Filed: July 15, 2016
    Date of Patent: March 17, 2020
    Assignees: EMV ENHANCE (HK) LIMITED, VERSITECH LIMITED
    Inventors: Fan Ngai Hung, Jinxia Zhang, Kai Wang Kelvin To, Johnson Yiu-Nam Lau, Kwok Yung Yuen
  • Publication number: 20200084843
    Abstract: The present invention discloses a device for plasma arc melting through magnetostatic soft-contact stirring and compounding, which includes a furnace body, where a water-cooled copper crucible and a tungsten electrode are mounted in the furnace body, the tungsten electrode is located above the water-cooled copper crucible, and a groove for containing a metal raw material is opened in the water-cooled copper crucible; and a drive shaft penetrates through a side wall of the water-cooled copper crucible, one end, located at the exterior of the water-cooled copper crucible, of the drive shaft is connected with a stepper motor, one end, located in the water-cooled copper crucible, of the drive shaft is sleeved with two rotary tables, magnets having reverse magnetisms are interleaved in the rotary table, and the rotary tables are located on two sides of the groove.
    Type: Application
    Filed: September 13, 2019
    Publication date: March 12, 2020
    Inventors: Zhongming Ren, Jianbo Yu, Xia Li, Fan Yang, Liang Liu, Yujia Zhang, Yang Kong
  • Patent number: 10585774
    Abstract: A method or apparatus for monitoring a system by detecting misbehaving components in the system is presented. A computing device receives historical data points based on a set of monitored signals of a system. The system has components that are monitored through the set of monitored signals. For each monitored component, the computing device performs unsupervised machine learning based on the historical data points to identify expected states and state transitions for the component. The computing device identifies one or more steady components based on the identified states of the monitored components. The computing device also receives real-time data points based on monitoring the set of signals from the system. For each identified steady component, the computing device examines the received real-time data points for deviation from the expected state and state transitions of the steady component. The computing device reports anomaly in the system based on the detected deviations.
    Type: Grant
    Filed: September 27, 2017
    Date of Patent: March 10, 2020
    Assignee: INTERNATIONAL BUSINESS MACHINES CORPORATION
    Inventors: Peng Fei Chen, Fan Jing Meng, Feng Wang, Yuan Wang, Jing Min Xu, Xiao Zhang
  • Publication number: 20200074220
    Abstract: This disclosure relates to improved techniques for performing multi-view image clustering. The techniques described herein utilize machine learning functions to optimize the image clustering process. Multi-view features are extracted from a collection of images. A machine learning function is configured to jointly learn a fused binary representation that combines the multi-view features and one or more binary cluster structures that can be used to partition the images. A clustering function utilizes the fused binary representation and the one or more binary cluster structures to generate one or more image clusters based on the collection of images.
    Type: Application
    Filed: September 4, 2018
    Publication date: March 5, 2020
    Inventors: Zheng Zhang, Li Liu, Jie Qin, Fan Zhu, Fumin Shen, Yong Xu, Ling Shao, Heng Tao Shen
  • Publication number: 20200072869
    Abstract: Resistivity probes can be used to test integrated circuits. In one example, a resistivity probe has a substrate with multiple vias and multiple metal pins. Each of the metal pins is disposed in one of the vias. The metal pins extend out of the substrate. Interconnects provide an electrical connection to the metal pins. In another example, a resistivity probe has a substrate with a top surface and multiple elements extending from the substrate. Each of the elements curves from the substrate to a tip of the element such that each of the elements is non-parallel to the top surface of the substrate.
    Type: Application
    Filed: November 10, 2019
    Publication date: March 5, 2020
    Inventors: Walter H. Johnson, III, Nanchang Zhu, Xianghua Liu, Jianli Cui, Zhu-bin Shi, Zhuoxian Zhang, Haiyang You, Lu Yu, Jianou Shi, Fan Zhang
  • Publication number: 20200073968
    Abstract: This disclosure relates to improved sketch-based image retrieval (SBIR) techniques. The SBIR techniques utilize a neural network architecture to train a domain migration function and a hashing function. The domain migration function is configured to transform sketches into synthetic images, and the hashing function is configured to generate hash codes from synthetic images and authentic images in a manner that preserves semantic consistency across the sketch and image domains. The hash codes generated from the synthetic images can be used for accurately identifying and retrieving authentic images corresponding to sketch queries, or vice versa.
    Type: Application
    Filed: September 4, 2018
    Publication date: March 5, 2020
    Inventors: Jingyi Zhang, Fumin Shen, Li Liu, Fan Zhu, Mengyang Yu, Ling Shao, Heng Tao Shen
  • Publication number: 20200076167
    Abstract: An expandable bused elbow is provided for connecting modular metering equipment around an inside corner. The expandable bused elbow comprises an enclosure configured to fit in a gap between modular equipment. The enclosure has a box assembly with a sliding mechanism that enables expansion of the box assembly. The expandable bused elbow further comprises a first bussed interior assembly enclosed within the enclosure having a first bottom end and a second bussed interior assembly enclosed within the enclosure having a second bottom end. The first bussed interior assembly has a first bussing expansion mechanism that enables expansion of the first bussed interior assembly. The second bussed interior assembly has a second bussing expansion mechanism that enables expansion of the second bussed interior assembly. The expandable bused elbow further comprises a center corner assembly disposed in a middle space between the first bussed interior assembly and the second bussed interior assembly.
    Type: Application
    Filed: November 5, 2019
    Publication date: March 5, 2020
    Inventors: Fan Zhang, Brian J. Rusch, Carey D. Harnois, Arthur Kevin Shumate
  • Publication number: 20200074443
    Abstract: Embodiments of the specification disclose a transaction execution method, apparatus, and device applicable in a client terminal and a server. The transaction execution method includes: scanning an offline object and a corresponding identification code thereof, the identification code comprising positioning assistance information of the offline object; triggering a recognition process for the offline object and the identification code; and executing a transaction with respect to the offline object based on a result of the recognition process.
    Type: Application
    Filed: November 6, 2019
    Publication date: March 5, 2020
    Inventors: Fan YANG, Huanmi YIN, Xiaodong ZENG, Feng LIN, Sihai YAO, Hong ZHANG
  • Publication number: 20200072395
    Abstract: A four-layer-structured water passing device is provided, in which a first sleeve and a second sleeve are disposed between an elastic inner tube and an outer cloth sheath. When the water passing device is connected with a pressurized water source, the first sleeve can quickly eliminate or reduce the impact wave strength when receiving a strong expansion impact from the elastic inner tube, such that the first sleeve can gently transmit the fluctuation to the second sleeve, and the second sleeve extends the outer cloth sheath to the limit length, so as to avoid damage caused by frequent direct contact friction between the elastic inner tube and the outer cloth sheath. The water passing device is also configured to avoid permanent deformation and abrasion at the joint position between the elastic inner tube and the outer cloth sheath, and thus prolong the service life of the water passing device.
    Type: Application
    Filed: January 16, 2019
    Publication date: March 5, 2020
    Inventors: Fan Zhang, Song Chen
  • Publication number: 20200062715
    Abstract: The present technology provides an isolated compound of Formula I, compositions including such compounds, methods of inhibiting TGF-? signaling and/or TGF-? induced epithelial mesenchymal transitions (EMT), and treating certain cancers involving TGF-? signaling and/or EMT.
    Type: Application
    Filed: August 26, 2019
    Publication date: February 27, 2020
    Inventors: Timothy Bugni, Fan Zhang, Douglas Braun, Gene Ananiev, F. Michael Hoffmann
  • Publication number: 20200068058
    Abstract: A method for turning off a display device in an electronic device controls a detecting device to detect various action parameters in a predetermined time period when a user is making or receiving a call by holding the device to his ear (to-ear call). A number of action parameters are set and several values for each parameter are established. Determining at least one action parameter having the number of values within a first predefined range to be a reference parameter and controlling the detecting device to detect the reference parameters of the electronic device for a to-ear call are provided. Determining whether each value of each reference parameter is within in a second predefined range and upon determining that a to-ear call is taking place, turning a display device off.
    Type: Application
    Filed: July 26, 2019
    Publication date: February 27, 2020
    Inventors: JUN-WEI ZHANG, SEN FAN