Abstract: The present application relates to a chip, a preparation method therefor, and an application thereof. The chip of embodiments of the present application comprises: a substrate having a surface grafted with an amino group, the amino group being a primary amino group or a secondary amino group; and a first compound linked to the surface via the amino group, the first compound comprising the following structure, i.e., formula (1) or formula (2), wherein R1 and R2 are each independently selected from —OH or C1-C5 alkoxy, and n is 1 or 2. The chip can be used for a nucleic acid test, such as single-molecule sequencing and next-generation sequencing.

Abstract: The present invention discloses an omnidirectionally adjustable mobile phone holder comprising: a mobile phone clamp having a supporting surface and a connecting surface; a support seat used to contact a position for placement; and a connecting piece connected with the connecting surface of the mobile phone clamp and the support seat. By means of arranging the connecting piece to enable the mobile phone clamp to be multi-directionally adjusted with respect to the support seat, it is convenient for users to adjust the position of the mobile phone towards the position suitable for themselves according to different usage requirements, improving the convenience of use; the magnetic accepter and the ball head are connected with each other by magnetic attraction, so that it is free to turn and adjust the mobile phone clamp for an angle, effectively improving the convenience of adjustment, and achieving omnidirectional adjustment in a wide range.

Abstract: A temporal distribution pattern-based medium-term streamflow forecasting method includes: acquiring and organizing long-series hydrological streamflow data from a control cross-section of a study basin, including flow data at daily, ten-day, monthly, seasonal, and yearly scales from a hydrological station and inflow data from a reservoir station; performing streamflow restoration calculation based on a water balance principle, and obtaining a natural streamflow series for any basin node; performing an inflow frequency analysis, and determining seasonal and monthly inflow frequencies of any node in different inflow years; calculating distribution ratios of each month's streamflow at any node across first, middle and last ten-day periods, and defining a temporal streamflow distribution coefficient for the corresponding month; and identifying a historical year with a similar characteristic based on a monthly natural flow at a specific cross-section, matching the temporal distribution coefficient of a historical

Abstract: The present disclosure discloses a method for preparing a spatial chip, a spatial chip, and a use thereof.

Abstract: Compositions and methods are provided for lamellar and defect reconstruction of corneal stromal tissue using biomaterials that form a defined hydrogel structure in situ, including interpenetrating (IPN) and semi-IPN hydrogels.

Abstract: The disclosure provides recombinant LAC polynucleotides encoding a laccase (LAC) polypeptide capable of polymerizing caffeyl alcohol, vectors and cells including the recombinant LAC polynucleotide. The disclosure also provides transgenic plants including cells having the recombinant LAC polynucleotide of the present disclosure and methods of increasing production of C-lignin in a plant.

Abstract: The present disclosure relates to the field of sequencing, and in particular to, a single-molecule sequencing method.

Abstract: The present application discloses an anti-interference control method, an electronic device, a base station, and a storage medium. The anti-interference control method comprises: if it is determined that an interference signal exists in target signals, acquiring a start frequency point and an end frequency point of the bandwidth of the interference signal (S110); and screening the target signals according to the start frequency point and the end frequency point to obtain a non-interference signal (S120).

Abstract: The present application relates to the technical field of metal ion chemistry, and provides a method for reducing an azidomethoxy group, a sequencing method, and a kit. The method for reducing the azidomethoxy group provided in the present application comprises: mixing a compound I comprising the azidomethoxy group, a palladium compound, and an organic phosphine to give a mixed system, and placing the mixed system under a condition suitable for a chemical reaction to reduce the azidomethoxy group of the compound I into hydroxy, wherein the azidomethoxy group has a chemical formula of —O—CA1(N3)-A2, and A1 is selected from one of hydrogen, substituted or unsubstituted hydrocarbyl, substituted or unsubstituted cyclic hydrocarbyl, substituted or unsubstituted heteroatom-containing hydrocarbyl, substituted or unsubstituted heteroatom-containing cyclic hydrocarbyl, substituted or unsubstituted aryl, and substituted or unsubstituted heteroaryl.

Abstract: The present disclosure generally relates to a two dimensional magnetic recording (TDMR) read head. The read head comprises a lower shield, a lower sensor disposed on the lower shield, a middle shield disposed over the lower sensor, an upper sensor disposed on the middle shield, and an upper shield disposed over the upper sensor. In one embodiment, the middle shield is a simple pinned shield comprising a first ferromagnetic (FM) layer, an antiferromagnetic (AFM) layer disposed on the first FM layer, and a second FM layer disposed on the AFM layer, and the upper shield is a synthetic antiferromagnetic (SAF) pinned shield comprising a first pinning layer, an antiferromagnetic coupling (AFC) layer disposed on the first pinning layer, and a second pinning layer disposed on the AFC layer. In another embodiment, the middle shield is a SAF pinned shield and the upper shield is a simple pinned shield.

Abstract: Components for multi-position ladders are provided. A ladder includes an outer ladder section with a first outer rail and a second outer rail, and an inner ladder section with a first inner rail and a second inner rail, the first inner rail extending within the first outer rail and the second inner rail extending within the second outer rail such that the outer ladder section and the inner ladder section are slidable relative to one another to change a position between the inner section and the outer section between a maximum contracted position and a maximum extended position. The ladder further includes a stop positioned on the first outer rail or the first inner rail, the stop positioned to stop relative movement of the inner ladder section and outer ladder section beyond the maximum contracted position. Braces for outer rails of a ladder are further provided.

Abstract: A work platform system having a first work platform. The first work platform having a first hook assembly and a first latch assembly. The system having a second work platform. The second work platform having a second hook assembly and a second latch assembly. The first work platform locked to the second work platform through the first hook assembly engaging with the second latch assembly and the first hook assembly in the use position. A method for using a work platform system. A method for producing a work platform.

Abstract: The present disclosure provides one embodiment of a semiconductor structure. The semiconductor structure includes a first active region and a second fin active region extruded from a semiconductor substrate; an isolation featured formed in the semiconductor substrate and being interposed between the first and second fin active regions; a dielectric gate disposed on the isolation feature; a first gate stack disposed on the first fin active region and a second gate stack disposed on the second fin active region; a first source/drain feature formed in the first fin active region and interposed between the first gate stack and the dielectric gate; a second source/drain feature formed in the second fin active region and interposed between the second gate stack and the dielectric gate; a contact feature formed in a first inter-level dielectric material layer and landing on the first and second source/drain features and extending over the dielectric gate.

Abstract: The present disclosure provides one embodiment of a semiconductor structure. The semiconductor structure includes a first active region and a second fin active region extruded from a semiconductor substrate; an isolation featured formed in the semiconductor substrate and being interposed between the first and second fin active regions; a dielectric gate disposed on the isolation feature; a first gate stack disposed on the first fin active region and a second gate stack disposed on the second fin active region; a first source/drain feature formed in the first fin active region and interposed between the first gate stack and the dielectric gate; a second source/drain feature formed in the second fin active region and interposed between the second gate stack and the dielectric gate; a contact feature formed in a first inter-level dielectric material layer and landing on the first and second source/drain features and extending over the dielectric gate.

Abstract: An integrated circuit includes a first standard cell having a first pFET and a first nFET integrated, and having a first dielectric gate on a first standard cell boundary. The integrated circuit further includes a second standard cell being adjacent to the first standard cell, having a second pFET and a second nFET integrated, and having a second dielectric gate on a second standard cell boundary. The integrated circuit also includes a first filler cell configured between the first and second standard cells, and spanning from the first dielectric gate to the second dielectric gate. The first pFET and the second pFET are formed on a first continuous active region. The first nFET and the second nFET are formed on a second continuous active region.

Abstract: Provided are a surface treatment method, a sequencing method, and a kit for nucleic acid molecule extension. The surface treatment method comprises: contacting a phosphate compound with a surface bound with an oligonucleotide, wherein the phosphate compound comprises a compound having a structural formula represented by formula (1) and/or formula (2). With regard to the problem that bases are prone to random adsorption on the surface of the sequencing chip in the sequencing process, it has been unexpectedly discovered that compounds with a specific structure can compete with virtual terminator bases in the sequencing process for adsorption on the surface of the sequencing chip, thus reducing the random adsorption of bases on the surface of the sequencing chip, reducing the resultant sequencing error rate, and improving the sequencing throughput.

Abstract: The present application relates to the field of biological technology, and provides a spatial chip, a method for preparing same, and use thereof. The spatial chip comprises a chip substrate comprising a first surface provided with a plurality of isolated single-stranded nucleic acid amplification clusters; each of the single-stranded nucleic acid amplification clusters comprises a plurality of single-stranded nucleic acid molecules with identical nucleotide sequences, and nucleotide sequences of different single-stranded nucleic acid amplification clusters are different; each of the single-stranded nucleic acid amplification clusters has a known physical coordinate set relative to the spatial chip; the single-stranded nucleic acid molecule comprises at least a barcode sequence with a known sequence, and the barcode sequences of each single-stranded nucleic acid amplification clusters are in one-to-one correspondence with the physical coordinate sets.

Abstract: Disclosed are a fluorescence detection reagent, a method for incorporating a labeled nucleotide by using the reagent, and a kit or a mixture system. The fluorescence detection reagent comprises an enzymatic deoxygenation system and a plurality of reducing agents, and does not comprise DABCO. The composition is suitable for an application scenario in relation to fluorescence signal detection, in particular an application comprising single molecule fluorescence signal detection.