Abstract: A packet sending method and a related device are disclosed. The method includes: A network device obtains a first packet, where an internet protocol extension header of the first packet includes a first identifier, and the first identifier indicates a service requirement corresponding to the first packet. The network device determines, based on the first identifier and a second identifier, path indication information corresponding to the first packet, where a destination address of the first packet includes the second identifier, and the path indication information herein includes one or more of a network slice identifier and a segment identifier list. The network device updates the first packet based on the path indication information to obtain a second packet, and sends the second packet.

Abstract: In a method for displaying relationship-based relationship indicators in a gaming interface, a team interface including a plurality of player positions is displayed. Player avatars at the plurality of player positions are displayed. Each player avatar corresponds to a respective team member of a plurality of team members. When a relationship is detected between at least two team members of the plurality of team members, relationship indicators at the plurality of player positions corresponding to the at least two team members are displayed. The relationship indicators indicate the relationship detected between the at least two team members. Apparatus and non-transitory computer-readable storage medium counterpart embodiments are also contemplated.

Abstract: This disclosure relates to compounds of Formula (A): Formula (A), or a pharmaceutically acceptable salt thereof, wherein DSM is a degradation signaling moiety that is covalently attached to the linker L, L is a linker that covalently attaches IRAK to DSM; and IRAK is an IRAK4 binding moiety represented by Formula (I) that is covalently attached to linker L; Formula (I) in which all of the variables are as defined in the application. Compounds or pharmaceutically acceptable salts thereof as described herein are capable of activating the selective ubiqitination of IRAK4 proteins via the ubiquitin-proteasome pathways (UPP) and cause degradation of IRAK4 proteins. The present disclosure also provides methods of treating disorders responsive to modulation of IRAK4 activity and/or degradation of IRAK4 with at least one compound described herein.

Abstract: This disclosure relates to compounds of Formula (A): IRAK-L-DSM (A), or a pharmaceutically acceptable salt thereof, wherein DSM is a degradation signaling moiety that is covalently attached to the linker L, L is a linker that covalently attaches IRAK to DSM; and IRAK is an IRAK4 binding moiety represented by Formula (I) that is covalently attached to linker L; in which all of the variables are as defined in the application. Compounds or pharmaceutically acceptable salts thereof as described herein are capable of activating the selective ubiqitination of IRAK4 proteins via the ubiquitin-proteasome pathways (UPP) and cause degradation of IRAK4 proteins. The present disclosure also provides methods of treating disorders responsive to modulation of IRAK4 activity and/or degradation of IRAK4 with at least one compound described herein.

Abstract: An optical lens set includes a first lens element of an object-side surface with a convex portion in a vicinity of an optical axis, a second lens element of an image-side surface with a concave portion in a vicinity of its periphery and a sixth lens element of an image-side surface with a convex portion in a vicinity of its periphery. T5min is the minimal distance from the object-side surface of the fifth lens element to the image-side surface of the fifth lens element and the fifth lens element has a fifth lens element thickness T5 along the optical axis to satisfy T5min/T5?0.6.

Abstract: A compound, as represented by formula I, as a TLR7 agonist, a method for preparing the compound, and the use of the compound in treating diseases mediated by the TLR7 agonist are provided. Studies on the activity of a human-derived receptor, a TLR7 agonist, show that compounds have a strong agonistic effect on the human-derived receptor, TLR7, and can be used as a foreground compound for treating diseases mediated by the TLR7 agonist.

Abstract: This disclosure relates to imidazo[1,2-a]pyridinyl derivatives of formula (I), or pharmaceutically acceptable salts thereof, Formula (I) in which all of the variables are as defined in the specification, capable of modulating the activity of IRAK4. The disclosure further provides methods to their preparation, to their medical use, in particular to their use in the treatment and management of diseases or disorders including inflammatory disease, autoimmune disease, cancer, cardiovascular disease, a disease of the central nervous system, disease of the skin, an ophthalmic disease and condition, and a bone disease.

Abstract: A network system includes a first network device, a second network device, and a third network device. The first network device is configured to: obtain a first route advertisement message, where the first route advertisement message includes a first route prefix; and obtain a second route prefix based on the first route prefix, where the second route prefix corresponds to a first network slice, and the second route prefix is a subnet prefix of the first route prefix. The first network device advertises a second route advertisement message to the second network device, where the second route advertisement message includes the second route prefix.

Abstract: A packet sending method and a related device are disclosed. The method includes: A network device obtains a first packet, where an internet protocol extension header of the first packet includes a first identifier, and the first identifier indicates a service requirement corresponding to the first packet. The network device determines, based on the first identifier and a second identifier, path indication information corresponding to the first packet, where a destination address of the first packet includes the second identifier, and the path indication information herein includes one or more of a network slice identifier and a segment identifier list. The network device updates the first packet based on the path indication information to obtain a second packet, and sends the second packet.

Abstract: A simulation system and a method thereof are disclosed. In the simulation system, a system power transmission model, and analog current time-domain model and digital current time-domain model are connected to obtain power noise generated after a supply current is obtained; jitter time-domain information of each interface connection circuit model under the power noise is obtained based on transmission of a clock signal outputted from a phase lock loop, by a simulation program; next, a voltage step response of a voltage measurement point when a clock terminal of each interface connection circuit model receives an ideal signal, is simulated by the simulation program to generate a first voltage time-domain model; a system waveform is generated based on the jitter time-domain information of each interface connection circuit model under the power noise, the first voltage time-domain model and data transmission, thereby obtaining an eye diagram and time-domain jitter distribution.

Abstract: Embodiments of this application provide a packet sending method and a device, to improve packet transmission efficiency. The method includes: A first network device receives a first packet from a second network device, where the first packet includes information about a first forwarding path, and the first forwarding path is a forwarding path for sending the first packet from the second network device to the first network device. The first network device obtains information about a second forwarding path based on the information about the first forwarding path, where the second forwarding path is a reverse path of the first forwarding path. The first network device sends a second packet to the second network device through the second forwarding path, where the second packet carries the information about the second forwarding path.

Abstract: This invention relates to Imidazo[1,2-a]pyridinyl Derivatives of formula (I?), or pharmaceutically acceptable salts thereof, in which all of the variables are as defined in the specification, capable of modulating the activity of IRAK4. The invention further provides a method of manufacturing compounds of the invention, and methods for their therapeutic use. The invention further provides methods to their preparation, to their medical use, in particular to their use in the treatment and management of diseases or disorders including inflammatory disease, autoimmune disease, cancer, cardiovascular disease, a disease of the central nervous system, disease of the skin, an ophthalmic disease and condition, and a bone disease.

Abstract: This invention relates to 2H-indazole Derivatives of formula (I?), or pharmaceutically acceptable salts thereof, in which all of the variables are as defined in the specification, capable of modulating the activity of IRAK4. The invention further provides a method of manufacturing compounds of the invention, and methods for their therapeutic use. The invention further provides methods to their preparation, to their medical use, in particular to their use in the treatment and management of diseases or disorders including inflammatory disease, autoimmune disease, cancer, cardiovascular disease, a disease of the central nervous system, disease of the skin, an ophthalmic disease and condition, and a bone disease.

Abstract: An error correction method and a time-interleaved analog-to-digital converter (TIADC) are provided. The method is applied to a TIADC that includes a plurality of analog-to-digital converters (ADCs), and the method includes: determining whether a current value of a codeword of a first ADC in the plurality of ADCs is within a preset range; when the current value of the codeword of the first ADC is not within the preset range, adjusting a plurality of codewords that are in a one-to-one correspondence with the plurality of ADCs; and controlling a clock frequency division circuit to generate, by using a plurality of adjusted codewords, a plurality of sampling clocks that are in a one-to-one correspondence with the plurality of ADCs. In embodiments of this application, a sampling time-period skew existing between ADCs may be adjusted by adjusting codewords corresponding to the ADCs.

Abstract: This invention relates to Imidazo[1,2-a]pyridinyl Derivatives of formula (I?), or pharmaceutically acceptable salts thereof, in which all of the variables are as defined in the specification, capable of modulating the activity of IRAK4. The invention further provides a method of manufacturing compounds of the invention, and methods for their therapeutic use. The invention further provides methods to their preparation, to their medical use, in particular to their use in the treatment and management of diseases or disorders including inflammatory disease, autoimmune disease, cancer, cardiovascular disease, a disease of the central nervous system, disease of the skin, an ophthalmic disease and condition, and a bone disease.

Abstract: A communication network, comprising a video server, adapted to generate a multicast video signal, and a first router is provided. The communication network is operated by a first communication provider. The first router is adapted to receive the multicast video signal, generate a plurality of unicast video signals from the multicast video signal, and provide each of the plurality of unicast video signals to one of a plurality of user devices, connected to a first further communication network, through at least a first further router, which is part of the first further communication network. The first further communication network is operated by a second communication provider.

Abstract: An error correction method and a time-interleaved analog-to-digital converter (TIADC) are provided. The method is applied to a TIADC that includes a plurality of analog-to-digital converters (ADCs), and the method includes: determining whether a current value of a codeword of a first ADC in the plurality of ADCs is within a preset range; when the current value of the codeword of the first ADC is not within the preset range, adjusting a plurality of codewords that are in a one-to-one correspondence with the plurality of ADCs; and controlling a clock frequency division circuit to generate, by using a plurality of adjusted codewords, a plurality of sampling clocks that are in a one-to-one correspondence with the plurality of ADCs. In embodiments of this application, a sampling time-period skew existing between ADCs may be adjusted by adjusting codewords corresponding to the ADCs.

Abstract: An optical lens set includes a first lens element of an object-side surface with a convex portion in a vicinity of an optical axis, a second lens element of an image-side surface with a concave portion in a vicinity of its periphery and a sixth lens element of an image-side surface with a convex portion in a vicinity of its periphery. T5min is the minimal distance from the object-side surface of the fifth lens element to the image-side surface of the fifth lens element and the fifth lens element has a fifth lens element thickness T5 along the optical axis to satisfy T5min/T5?0.6.