Patents by Inventor Fang Shen
Fang Shen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240141549Abstract: The present disclosure discloses a preparation method of an aluminum nitride (AlN) composite structure based on a two-dimensional (2D) crystal transition layer. The preparation method of the present disclosure includes: transferring the 2D crystal transition layer on a first periodic groove of an epitaxial substrate; forming a second periodic groove staggered with the first periodic groove on the 2D crystal transition layer; depositing a supporting protective layer; depositing a functional layer of a required AlN-based material; and removing the 2D crystal transition layer through thermal oxidation to obtain a semi-suspended AlN composite structure. The preparation method of the present disclosure has low difficulty and is suitable for large-scale industrial production.Type: ApplicationFiled: October 31, 2023Publication date: May 2, 2024Applicant: PEKING UNIVERSITYInventors: Xinqiang WANG, Fang LIU, Zhaoying CHEN, Bowen SHENG, Yucheng GUO, Bo SHEN
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Publication number: 20240145641Abstract: A color conversion panel and a display device are provided. The color conversion panel includes an opaque substrate and a sapphire substrate. The opaque substrate includes a plurality of first pixel openings, a plurality of second pixel openings and a plurality of third pixel openings. The first pixel openings are filled with red quantum dot material, and the second pixel openings are filled with green quantum dot material. The sapphire substrate is on the opaque substrate. A first surface of the sapphire substrate that faces the opaque substrate has a plurality of first arc surfaces corresponding to the first pixel openings, a plurality of second arc surfaces corresponding to the second pixel openings, and a plurality of third arc surfaces corresponding to the third pixel openings.Type: ApplicationFiled: December 15, 2022Publication date: May 2, 2024Applicant: Industrial Technology Research InstituteInventors: Kai-Ling Liang, Wei-Hung Kuo, Hui-Tang Shen, Chun-I Wu, Suh-Fang Lin
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Publication number: 20240130156Abstract: A light-emitting element includes a pair of electrodes, a first light-emitting unit, a second light-emitting unit, and a charge generation layer. The first light-emitting unit, between the pair of electrodes, and the first light-emitting unit, includes a first light-emitting layer. The second light-emitting unit, between the pair of electrodes, includes a second light-emitting layer. A first luminescent layer includes a first main body material, a second main body material, a first guest material, and a first auxiliary material, and the first main body material forms a first excimer complex with the second main body material. A first excited triplet state energy level of the first auxiliary material is lower than a first excited triplet state energy level of the first excimer complex, and the first excited triplet state energy level of the first auxiliary material is higher than that of the first guest material.Type: ApplicationFiled: September 26, 2023Publication date: April 18, 2024Applicant: WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD.Inventors: Yu ZHANG, Li YUAN, Munjae LEE, Wenxu XIANYU, Jie YANG, Huizhen PIAO, Mugyeom KIM, Xianjie LI, Jing HUANG, Fang WANG, Kailong WU, Lin YANG, Yu GU, Mingzhou WU, Jingyao SONG, Danhua SHEN, Guo CHENG
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Publication number: 20240124583Abstract: Embodiments of the present invention provide isolated proteins comprising antigen binding domains that bind kallikrein related peptidase 2 (hK2), including monospecific and bispecific antibodies. Additional embodiments of the invention provide polynucleotides encoding the hk2-specific proteins, vectors, host cells, and methods of making and using them.Type: ApplicationFiled: December 27, 2023Publication date: April 18, 2024Inventors: Rajkumar Ganesan, John Lee, Jinquan Luo, Theresa McDevitt, Fei Shen, Degang Song, Raymond Brittingham, Sathyadevi Venkataramani, Sanjaya Singh, Yonghong Zhao, Fang Yi, Sherry Lynn LaPorte
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Publication number: 20240092922Abstract: This disclosure relates to anti-TNFRSF9 (tumor necrosis factor receptor superfamily member 9) antibodies, antigen-binding fragments, and the uses thereof.Type: ApplicationFiled: September 11, 2023Publication date: March 21, 2024Inventors: Yi Yang, Jingshu Xie, Chunyan Dong, Fang Yang, Chengyuan Lu, Yuelei Shen, Jian Ni, Yanan Guo, Yunyun Chen
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Publication number: 20240092987Abstract: Described herein are conductive elastomeric foam materials and methods of making and using the same. The conductive elastomeric foam materials include a polymeric matrix, one or more conductive fillers, and one or more foaming agents. The polymeric matrix can include a thermoset polymer or a thermoplastic polymer. Also described herein are methods of making conductive elastomeric foam materials. Further described herein are molded products including the conductive elastomeric foam materials as described herein and wearable devices including the molded products.Type: ApplicationFiled: September 14, 2023Publication date: March 21, 2024Inventors: Li Yao, Wenyang Pan, Ziyan Liu, Shawn Reese, Thomas John Farrell Wallin, Zhenzhen Shen, Fang He, Robert Cole Bolger-Cruz, Sudhanshu Rathod, Kristopher Erickson
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Publication number: 20240084357Abstract: An oligopeptide with lipid-lowering activity, a preparation method and an application thereof are provided, belonging to the field of biotechnology. The amino acid sequence of the oligopeptide with lipid-lowering activity is shown in SEQ ID NO: 1. The preparation method includes the following steps: (1) hydrolyzing a loach protein with proteases to obtain an enzymatic hydrolysis product; (2) separating the enzymatic hydrolysis product using an ultrafiltration membrane, and taking a component with a molecular weight less than 3 kilodalton (kDa); and (3) filtering and separating the component with the molecular weight less than 3 kDa by Sephadex G-15 to obtain the oligopeptide. The oligopeptide is derived from the loach protein and has the characteristics of high safety, high efficiency, and wide sources.Type: ApplicationFiled: September 6, 2023Publication date: March 14, 2024Inventors: Fang Wang, Xinchun Shen, Yong Fang, Zebin Weng
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Publication number: 20220315557Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, R6, R5, G1, and G2 are defined herein.Type: ApplicationFiled: November 25, 2020Publication date: October 6, 2022Inventors: Tianbao LU, Brett Douglas Allison, Joseph Kent Barbay, Peter J. Connolly, Maxwell David Cummings, Gaston Diels, James Patrick Edwards, Kevin D. Kreutter, Ulrike Philippar, Fang Shen, Johannes Wilhelmus John Fitzgerald Thuring, Tongfei Wu, Didier Jean-Claude Berthelot
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Patent number: 11428439Abstract: A tile or plate, includes: an upper plate (3) and a lower plate (4); wherein a plurality of heat conducting cavities (6) are uniformly provided between the upper plate (3) and the lower plate (4) via connecting ribs (5). A solar collection layer is provided on an upper surface of the tile or the plate. Two ends of the tile or the plate are connected with each of the plurality of the heat conducting cavities (6) via transverse connecting pipes (23, 37, 42). The transverse connecting pipes (23, 37, 42) of two neighboring tiles are connected by a ferrule (17) or a hose (36) to form an integrated circulation system. The tile or plate has a large day-lighting area and a high energy conversion rate.Type: GrantFiled: July 24, 2014Date of Patent: August 30, 2022Assignee: BEIJING WADENER TECHNOLOGY CO. LTDInventors: Yunliang Qu, Jian Cui, Zhixiang Ying, Fang Shen, Bin Qu, Xinrong Wang, Chen Zhang, Xiangdong Li, Hongxing Wang
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Patent number: 11390845Abstract: Provided is a method for manufacturing cell-containing blocks having steps of: preparing an standardized size mold by 3D printing (three dimensional printing) using a biocompatible elastic material; injecting a thermosensitive colloid into the mold to form a thermosensitive mold; injecting a hydrogel containing cells in to the thermosensitive mold and curing the hydrogel containing cells to form the cell-containing blocks; separating the thermosensitive mold and the cell-containing blocks at a temperature higher than a solidifying point of the thermosensitive colloid. Also provided are method for assembling the cell-containing blocks in a target configuration by using an assembling mold defining the target configuration and made of a thermoreversible material.Type: GrantFiled: June 20, 2019Date of Patent: July 19, 2022Assignee: Asia UniversityInventors: Yu Fang Shen, Ming You Shie, Yi Wen Chen, Wei Huang Wang
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Patent number: 11188705Abstract: An efficient electronic structure for circuit design, testing and/or manufacture for validating a cell layout design using an intelligent engine trained using selectively arranged cells selected from a cell library. An initial design rule violation (DRV) prediction engine is initially trained using a plurality of pin patterns generated by predefined cell placement combinations, where pin patterns are pixelized and quantified and is classified as either (i) a DRV pin pattern (i.e., pin patterns likely to produce a DRV) or (ii) a DRV-clean pin pattern (i.e., pin patterns unlikely to produce a DRV).Type: GrantFiled: May 15, 2020Date of Patent: November 30, 2021Assignee: Synopsys, Inc.Inventors: Tao-Chun Yu, Hsien-Shih Chiu, Shao-Yun Fang, Kai-Shun Hu, Philip Hui-Yuh Tai, Cindy Chin-Fang Shen, Henry Sheng
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Patent number: 11040031Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, and G, are defined herein.Type: GrantFiled: June 13, 2019Date of Patent: June 22, 2021Assignee: Janssen Pharmaceutica NVInventors: Tianbao Lu, Peter J. Connolly, Maxwell David Cummings, Joseph Kent Barbay, Kevin D. Kreutter, Tongfei Wu, Gaston Stanislas Marcella Diels, Jan Willem Thuring, Ulrike Philippar, James Patrick Edwards, Fang Shen
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Patent number: 10954214Abstract: Disclosed are compounds, compositions and methods for treating of diseases, syndromes, conditions, and disorders that are affected by the modulation of MALT1. Such compounds are represented by Formula (I) as follows: wherein R1, R2, R3, R4, R5, R6, R5, G1, and G2 are defined herein.Type: GrantFiled: December 20, 2017Date of Patent: March 23, 2021Assignee: Janssen Pharmaceutica NVInventors: Tianbao Lu, Brett Douglas Allison, Joseph Kent Barbay, Peter J. Connolly, Maxwell David Cummings, Gaston Diels, James Patrick Edwards, Kevin D. Kreutter, Ulrike Philippar, Fang Shen, Johannes Wilhelmus John Fitzgerald Thuring, Tongfei Wu, Didier Jean-Claude Berthelot
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Publication number: 20200364394Abstract: An efficient electronic structure for circuit design, testing and/or manufacture for validating a cell layout design using an intelligent engine trained using selectively arranged cells selected from a cell library. An initial design rule violation (DRV) prediction engine is initially trained using a plurality of pin patterns generated by predefined cell placement combinations, where pin patterns are pixelized and quantified and is classified as either (i) a DRV pin pattern (i.e., pin patterns likely to produce a DRV) or (ii) a DRV-clean pin pattern (i.e., pin patterns unlikely to produce a DRV).Type: ApplicationFiled: May 15, 2020Publication date: November 19, 2020Inventors: Tao-Chun Yu, Hsien-Shih Chiu, Shao-Yun Fang, Kai-Shun Hu, Philip Hui-Yuh Tai, Cindy Chin-Fang Shen, Henry Sheng
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Publication number: 20200276198Abstract: The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of an HBV capsid assembly inhibitor and an interferon for use in the treatment of hepatitis B virus infections.Type: ApplicationFiled: March 20, 2020Publication date: September 3, 2020Applicant: Hoffmann-La Roche Inc.Inventors: Lu Gao, Isabel Najera, Hong Shen, Fang Shen, Liping Shi, Steffen Wildum, Guang Yang
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Publication number: 20200221944Abstract: A virtual reality-based ophthalmic inspection system includes a wearable unit, an electronic unit, and at least one detector. The wearable unit is available for an inspected object to wear the wearable unit on head. The electronic unit is assembled with the wearable unit and has a left-eye display zone and a right-eye display zone. A first visual acuity of the inspected object is identified according to a first eyesight information. The electronic unit performs a visual correction confirmation process, the at least one detector detects a condition value of corresponding the right eye and/or the left eye, and the electronic unit answers a first comparison result after comparing the condition value with a threshold value.Type: ApplicationFiled: March 26, 2020Publication date: July 16, 2020Inventors: Ho-Fang SHEN, Ming-Fu CHEN
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Patent number: 10624536Abstract: A virtual reality-based ophthalmic inspection system includes a wearable unit, an electronic unit, and at least one detector; the wearable unit is available for an inspected object to wear the wearable unit on head; the electronic unit is assembled with the wearable unit and has a left-eye display zone and a right-eye display zone, wherein the left-eye display zone is used for displaying at least one left-eye sight-targets, and the right-eye display zone is used for displaying at least one right-eye sight-targets; the detector is disposed on the electronic unit. A sight-target with at least one distinguishing feature are shown on one of the left-eye display zone and the right-eye display zone, the left-eye display zone displays the sight-target while the right-eye display zone is filled with black, and the right-eye display zone displays the sight-target while the left-eye display zone is filled with black.Type: GrantFiled: June 5, 2018Date of Patent: April 21, 2020Inventors: Ho-Fang Shen, Ming-Fu Chen
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Patent number: 10596173Abstract: The present invention is directed to compositions and methods for treating hepatitis B virus infection. In particular, the present invention is directed to a combination therapy comprising administration of an HBV capsid assembly inhibitor and an interferon for use in the treatment of hepatitis B virus infections.Type: GrantFiled: May 3, 2018Date of Patent: March 24, 2020Assignee: Hoffmann-La Roche Inc.Inventors: Lu Gao, Isabel Najera, Hong Shen, Fang Shen, Liping Shi, Steffen Wildum, Guang Yang
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Publication number: 20200010571Abstract: The present invention relates to bispecific anti-TNF-?/IL-17A antibodies and anti-TNF-? antibodies, polynucleotides encoding the antibodies or fragments, and methods of making and using the foregoing.Type: ApplicationFiled: September 11, 2019Publication date: January 9, 2020Inventors: Mark Chiu, Jennifer Nemeth-Seay, Tatiana Ort, Fang Shen
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Publication number: 20190390162Abstract: Provided is a method for manufacturing cell-containing blocks having steps of: preparing an standardized size mold by 3D printing (three dimensional printing) using a biocompatible elastic material; injecting a thermosensitive colloid into the mold to form a thermosensitive mold; injecting a hydrogel containing cells in to the thermosensitive mold and curing the hydrogel containing cells to form the cell-containing blocks; separating the thermosensitive mold and the cell-containing blocks at a temperature higher than a solidifying point of the thermosensitive colloid. Also provided are method for assembling the cell-containing blocks in a target configuration by using an assembling mold defining the target configuration and made of a thermoreversible material.Type: ApplicationFiled: June 20, 2019Publication date: December 26, 2019Inventors: Yu Fang Shen, Ming You Shie, Yi Wen Chen, Wei Huang Wang