Patents by Inventor Fang-Tsyr Lin

Fang-Tsyr Lin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating cancer that overexpresses TopBP1
    Patent number: 9636323
    Abstract: The present invention provides a method of treating cancer that overexpresses TopBP1 by administering to a patient suffering from the cancer with an effective amount of a small molecule inhibitor that binds the BRCT7/8 domain of TopBP1.
    Type: Grant
    Filed: October 23, 2015
    Date of Patent: May 2, 2017
    Assignee: Baylor College of Medicine
    Inventors: Weei-Chin Lin, Pinki Chowdhury, Gregory E. Lin, Kang Liu, Yongcheng Song, Fang-Tsyr Lin
  • Method of Treating Cancer That Overexpresses TopBP1
    Publication number: 20160113899
    Abstract: The present invention provides a method of treating cancer that overexpresses TopBP1 by administering to a patient suffering from the cancer with an effective amount of a small molecule inhibitor that binds the BRCT7/8 domain of TopBP1.
    Type: Application
    Filed: October 23, 2015
    Publication date: April 28, 2016
    Inventors: Weei-Chin Lin, Pinki Chowdhury, Gregory E. Lin, Kang Liu, Yongcheng Song, Fang-Tsyr Lin
  • Inhibition of betaarrestin mediated effects prolongs and potentiates opioid receptor-mediated analgesia
    Publication number: 20030097671
    Abstract: The present invention provides a &bgr;arrestin knockout mouse useful for screening compounds for efficacy in controlling pain, methods of controlling pain in subjects by inhibiting binding of &bgr;arrestin to phosphorylated &mgr; opioid receptors, and methods of screening a compound for activity in potentiating &mgr; opioid receptor agonist activity (e.g., morphine activity) by determining whether or not said compound inhibits &bgr;arrestin binding to a phosphorylated &mgr; opioid receptor.
    Type: Application
    Filed: January 3, 2003
    Publication date: May 22, 2003
    Inventors: Laura M. Bohn, Fang-Tsyr Lin, Marc G. Caron, Robert J. Lefkowitz
  • Inhibition of &bgr;arrestin mediated effects prolongs and potentiates opioid receptor-mediated analgesia
    Patent number: 6528271
    Abstract: The present invention provides a &bgr;arrestin knockout mouse useful for screeening compounds for efficacy in controlling pain, methods of controlling pain in subjects by inhibiting binding of &bgr;arrestin to phosphorylated &mgr; opioid receptors, and methods of screening a compound for activity in potentiating &mgr; opioid receptor agonist activity (e.g., morphine activity) by determining whether or not said compound inhibits &bgr;arrestin binding to a phosphorylated &mgr; opioid receptor.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: March 4, 2003
    Assignee: Duke University
    Inventors: Laura M. Bohn, Fang-Tsyr Lin, Marc G. Caron, Robert J. Lefkowitz