Patents by Inventor Fang Yi Su

Fang Yi Su has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220381781
    Abstract: CRISPR-based diagnostic methods and compositions are provided. One embodiment provides the use of DNA-barcoded antibodies or peptide-MHC (pMHC) tetramers (e.g., Kb-OVA257-264, Db-GP10025-33, Db-GP33-41) and CRISPR-Cas protein, and a guided DNA endonuclease, to achieve ultrasensitive detection of soluble and cell surface proteins. The disclosed embodiments can use type V: Cas12a; type VI: Cas13a, or Cas13b. Combining DNA encoding with CRISPR-Cas protein recognition is a sensitive system because barcodes can be isothermally amplified and Cas, for example Cas12a, enzymatically cleaves DNA reporters upon barcode detection, providing two rounds of amplification and enabling measurement of protein concentration by sample fluorescence or using by paper-based assays.
    Type: Application
    Filed: October 16, 2020
    Publication date: December 1, 2022
    Applicant: GEORGIA TECH RESEARCH CORPORATION
    Inventors: Gabriel A. KWONG, Shreyas DAHOTRE, Yun Min CHANG, Adrian HARRIS, Fang-Yi SU
  • Publication number: 20220368146
    Abstract: A method, charging device, and non-transitory computer readable medium for detecting charging state comparing obtaining data packages from a chargeable electrical device, each of the data packages comprising a first transmitting power; counting a quantity of the data packages of the first transmitting power data package being smaller than a theoretical transmitting power in a predetermined time period; and based on the quantity of the data packages, determining whether the chargeable electrical device is fully charged.
    Type: Application
    Filed: January 10, 2022
    Publication date: November 17, 2022
    Inventors: GANG YANG, JIAN-FENG SU, FANG-YI ZHOU
  • Publication number: 20190365906
    Abstract: Provided herein are particles assemblies including a shell surrounding a core. The shell includes a particle-stabilizing random copolymer. The core includes a core random copolymer. The particle assemblies have a biomimetic design in which the polymeric components containing discrete chemical and biological functionalities are designed to spontaneously self-assemble into particles. Also provided herein are random copolymers having conjugated therapeutic agents that can be cleaved from the copolymers by an enzyme or water.
    Type: Application
    Filed: April 11, 2019
    Publication date: December 5, 2019
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Patrick S. Stayton, Anthony Convertine, Daniel M. Ratner, Selvi Srinivasan, Debobrato Das, Fang-Yi Su, Jasmin Chen, David Yee-Shawn Chiu, Daniel Douglas Lane
  • Publication number: 20160279251
    Abstract: Provided herein are particles assemblies including a shell surrounding a core. The shell includes a particle-stabilizing random copolymer. The core includes a core random copolymer. The particle assemblies have a biomimetic design in which the polymeric components containing discrete chemical and biological functionalities are designed to spontaneously self-assemble into particles. Also provided herein are random copolymers having conjugated therapeutic agents that can be cleaved from the copolymers by an enzyme or water.
    Type: Application
    Filed: November 12, 2014
    Publication date: September 29, 2016
    Applicant: University of Washington through its Center for Commercialization
    Inventors: Patrick S. Stayton, Anthony Convertine, Daniel M. Ratner, Selvi Srinivasan, Debobrato Das, Fang-Yi Su, Jasmin Chen, David Yee-Shawn Chiu, Daniel Douglas Lane
  • Publication number: 20140312272
    Abstract: A method for manufacturing a carbon dioxide adsorbent is provided. The method comprises steps of providing a limestone having a first specific surface area, treating the limestone with acid solution to obtain a first substance having a second specific surface area larger than the first specific surface area, at the same time reacting the first substance with an anti-sintering agent to obtain a second substance, and calcining the second substance to obtain the carbon dioxide adsorbent containing calcium-based oxides.
    Type: Application
    Filed: September 12, 2013
    Publication date: October 23, 2014
    Inventors: San-Yuan Chen, Fang-Yi Su, Po-Hsueh Chang
  • Patent number: 8574544
    Abstract: The invention discloses a pharmaceutical composition of nanoparticles consisting of chitosan, a negatively charged substrate, and at least one bioactive agent that is encapsulated within cucurbiturils for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: November 5, 2013
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Ha Giang Thi Nguyen, Fang Yi Su, Er-Yuan Chuang, Zi-Xian Liao, Hosheng Tu
  • Patent number: 8535640
    Abstract: The invention discloses a composition of nanoparticles composed of positively charged chitosan, one negatively charged substrate, and optionally a zero-charge compound or at least one tumor necrosis factor inhibitor for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.
    Type: Grant
    Filed: February 25, 2013
    Date of Patent: September 17, 2013
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Ha Giang Thi Nguyen, Fang Yi Su, Li-Wen Hsu, Er-Yuan Chung, Hosheng Tu
  • Patent number: 8361346
    Abstract: The invention provides a phosphor composed of (M1?xREx)5SiO4?yX6+2y, wherein M is Ba individually or in combination with at least one of Mg, Ca, Sr, or Zn; RE is Y, La, Pr, Nd, Eu, Gd, Tb, Ce, Dy, Yb, Er, Sc, Mn, Zn, Cu, Ni, or Lu; X is F, Cl, Br, or combinations thereof; 0.001?x?0.6, and 0.001?y?1.5. Under excitation, the phosphor of the invention emits visible light and may be collocated with other phosphors to provide a white light illumination device.
    Type: Grant
    Filed: December 28, 2009
    Date of Patent: January 29, 2013
    Assignee: Industrial Technology Research Institute
    Inventors: Wei-Jen Liu, Yi-Chen Chiu, Yao-Tsung Yeh, Shyue-Ming Jang, Teng-Ming Chen, Jen-Chuen Liao, Li-Ching Chuo, Fang-Yi Su
  • Patent number: 8287905
    Abstract: The invention discloses a composition of chitosan-shelled nanoparticles and methods of manufacturing. The chitosan-shelled nanoparticles are characterized with a positive surface charge and enhanced epithelial permeability for oral drug delivery.
    Type: Grant
    Filed: April 3, 2012
    Date of Patent: October 16, 2012
    Assignees: GP Medical, Inc., National Tsing Hua Univresity
    Inventors: Hsing-Wen Sung, Er-Yuan Chuang, Ha Giang Thi Nguyen, Fang Yi Su, Kiran Sonaje, Hosheng Tu
  • Patent number: 8226928
    Abstract: The invention discloses nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent, wherein the bioactive agent may include mitofusin 1, mitofusin 2, and/or anti-diabetic compounds.
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: July 24, 2012
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Ho-Ngoc Nguyen, Ha Giang Thi Nguyen, Fang Yi Su, Er-Yuan Chuang, Hosheng Tu
  • Publication number: 20110050086
    Abstract: The invention provides a phosphor composed of (M1?xREx)5SiO4?yX6+2y, wherein M is Ba individually or in combination with at least one of Mg, Ca, Sr, or Zn; RE is Y, La, Pr, Nd, Eu, Gd, Tb, Ce, Dy, Yb, Er, Sc, Mn, Zn, Cu, Ni, or Lu; X is F, Cl, Br, or combinations thereof; 0.001?x?0.6, and 0.001?y?1.5. Under excitation, the phosphor of the invention emits visible light and may be collocated with other phosphors to provide a white light illumination device.
    Type: Application
    Filed: December 28, 2009
    Publication date: March 3, 2011
    Applicant: INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE
    Inventors: Wei-Jen Liu, Yi-Chen Chiu, Yao-Tsung Yeh, Shyue-Ming Jang, Teng-Ming Chen, Jen-Chuen Liao, Li-Ching Chuo, Fang-Yi Su