Abstract: An active stylus receiving circuit receives a vector data signal transmitted by an active stylus. The vector data signal carries vector data. The vector data includes in-phase data and quadrature data. The active stylus receiving circuit includes an analog-to-digital converter, an interpolation circuit and a demodulation circuit. The analog-to-digital converter samples and converts the vector data signal into digital signal with a plurality of sampling points. The interpolation circuit performs interpolating operation on the digital signal, so as to increase the number of sampling points representing the digital signal, and generate interpolated digital signal. The demodulation circuit performs demodulating operation on the interpolated digital signal to generate demodulated in-phase data and demodulated quadrature data, thereby obtaining demodulated vector data.

Abstract: The various described embodiments provide a CMP system and a method of using the same. The CMP system includes an imaging device, such as a laser scanner, that obtains an image of a dresser of the CMP system in real time or in-situ with a CMP process. A processing device of the CMP system compares the obtained image with one or more of reference images to determine whether or not the dresser has a defect. The processing device then adjusts the CMP process based on whether or not the dresser includes a defect.

Abstract: CRISPR-based diagnostic methods and compositions are provided. One embodiment provides the use of DNA-barcoded antibodies or peptide-MHC (pMHC) tetramers (e.g., Kb-OVA257-264, Db-GP10025-33, Db-GP33-41) and CRISPR-Cas protein, and a guided DNA endonuclease, to achieve ultrasensitive detection of soluble and cell surface proteins. The disclosed embodiments can use type V: Cas12a; type VI: Cas13a, or Cas13b. Combining DNA encoding with CRISPR-Cas protein recognition is a sensitive system because barcodes can be isothermally amplified and Cas, for example Cas12a, enzymatically cleaves DNA reporters upon barcode detection, providing two rounds of amplification and enabling measurement of protein concentration by sample fluorescence or using by paper-based assays.

Abstract: Provided herein are particles assemblies including a shell surrounding a core. The shell includes a particle-stabilizing random copolymer. The core includes a core random copolymer. The particle assemblies have a biomimetic design in which the polymeric components containing discrete chemical and biological functionalities are designed to spontaneously self-assemble into particles. Also provided herein are random copolymers having conjugated therapeutic agents that can be cleaved from the copolymers by an enzyme or water.

Abstract: Provided herein are particles assemblies including a shell surrounding a core. The shell includes a particle-stabilizing random copolymer. The core includes a core random copolymer. The particle assemblies have a biomimetic design in which the polymeric components containing discrete chemical and biological functionalities are designed to spontaneously self-assemble into particles. Also provided herein are random copolymers having conjugated therapeutic agents that can be cleaved from the copolymers by an enzyme or water.

Abstract: A method for manufacturing a carbon dioxide adsorbent is provided. The method comprises steps of providing a limestone having a first specific surface area, treating the limestone with acid solution to obtain a first substance having a second specific surface area larger than the first specific surface area, at the same time reacting the first substance with an anti-sintering agent to obtain a second substance, and calcining the second substance to obtain the carbon dioxide adsorbent containing calcium-based oxides.

Abstract: The invention discloses a pharmaceutical composition of nanoparticles consisting of chitosan, a negatively charged substrate, and at least one bioactive agent that is encapsulated within cucurbiturils for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.

Abstract: The invention discloses a composition of nanoparticles composed of positively charged chitosan, one negatively charged substrate, and optionally a zero-charge compound or at least one tumor necrosis factor inhibitor for oral delivery. The chitosan-based nanoparticles are characterized with a positive surface charge and enhanced permeability for oral drug delivery.

Abstract: The invention provides a phosphor composed of (M1?xREx)5SiO4?yX6+2y, wherein M is Ba individually or in combination with at least one of Mg, Ca, Sr, or Zn; RE is Y, La, Pr, Nd, Eu, Gd, Tb, Ce, Dy, Yb, Er, Sc, Mn, Zn, Cu, Ni, or Lu; X is F, Cl, Br, or combinations thereof; 0.001?x?0.6, and 0.001?y?1.5. Under excitation, the phosphor of the invention emits visible light and may be collocated with other phosphors to provide a white light illumination device.

Abstract: The invention discloses a composition of chitosan-shelled nanoparticles and methods of manufacturing. The chitosan-shelled nanoparticles are characterized with a positive surface charge and enhanced epithelial permeability for oral drug delivery.

Abstract: The invention discloses nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent, wherein the bioactive agent may include mitofusin 1, mitofusin 2, and/or anti-diabetic compounds.

Abstract: The invention provides a phosphor composed of (M1?xREx)5SiO4?yX6+2y, wherein M is Ba individually or in combination with at least one of Mg, Ca, Sr, or Zn; RE is Y, La, Pr, Nd, Eu, Gd, Tb, Ce, Dy, Yb, Er, Sc, Mn, Zn, Cu, Ni, or Lu; X is F, Cl, Br, or combinations thereof; 0.001?x?0.6, and 0.001?y?1.5. Under excitation, the phosphor of the invention emits visible light and may be collocated with other phosphors to provide a white light illumination device.