Abstract: A ventilation air pressure oscillation mitigation device for a ventilator includes a housing defining an inlet and an outlet. The device includes a valve seat defining a primary opening and a plurality of secondary openings. A valve body is selectively positionable in a first position and a second position within the device. In the first position, substantially all of a first flow of ventilation air from the inlet to the outlet passes through the primary opening. When the valve body is in the second position, all of a second flow of ventilation air from the inlet to the outlet passes through the plurality of secondary openings. An actuator controls a position of the valve body.

Abstract: A power control device includes a first terminal, a second terminal connected to a transmission line, a first cascade multilevel inverter (CMI) and a second CMI. The first CMI is connected to the second terminal. The second CMI connected in series between the first terminal and the second terminal.

Abstract: Butyrylcholinesterase (BChE) polypeptide variants of the presently-disclosed subject matter have enhanced catalytic efficiency for (?)-cocaine, as compared to wild-type BChE. Pharmaceutical compositions of the presently-disclosed subject matter include a BChE polypeptide variant having an enhanced catalytic efficiency for (?)-cocaine. A method of the presently-disclosed subject matter for treating a cocaine-induced condition includes administering to an individual an effective amount of a BChE polypeptide variant, as disclosed herein, to lower blood cocaine concentration.

Abstract: One or more test features are extracted from a time domain signal. The test features are represented by discrete data. The discrete data is represented for each of the one or more test features by a corresponding one or more fitting functions, which are defined in terms of finite number of continuous basis functions and a corresponding finite number of expansion coefficients. Each fitting function is compressed through Functional Principal Component Analysis (FPCA) to generate corresponding sets of principal components. Each principal component for a given test feature is uncorrelated to each other principal component for the given test feature. A distance between a set of principal components for the given test feature and a set of principal components for one or more training features with the processing system is calculated. The test feature is classified according to the distance calculated with the processing system.

Abstract: Butyrylcholinesterase (BChE) polypeptide variants of the presently-disclosed subject matter have enhanced catalytic efficiency for (?)-cocaine, as compared to wild-type BChE. Pharmaceutical compositions of the presently-disclosed subject matter include a BChE polypeptide variant having an enhanced catalytic efficiency for (?)-cocaine. A method of the presently-disclosed subject matter for treating a cocaine-induced condition includes administering to an individual an effective amount of a BChE polypeptide variant, as disclosed herein, to lower blood cocaine concentration.

Abstract: A power control device includes a first terminal, a second terminal connected to a transmission line, a first cascade multilevel inverter (CMI) and a second CMI. The first CMI is connected to the second terminal. The second CMI connected in series between the first terminal and the second terminal.

Abstract: An improved gate drive circuit is provided for a power device, such as a transistor. The gate driver circuit may include: a current control circuit; a first secondary current source that is used to control the switching transient during turn off of the power transistor and a second secondary current source that is used to control the switching transient during turn on of the power transistor. In operation, the current control circuit operates, during turn on of the power transistor, to source a gate drive current to a control node of the power transistor and, during turn off of the power transistor, to sink a gate drive current from the control node of the power transistor. The first and second secondary current sources adjust the gate drive current to control the voltage or current rate of change and thereby the overshoot during the switching transient.

Abstract: Butyrylcholinesterase (BChE) polypeptide variants of the presently-disclosed subject matter have enhanced catalytic efficiency for (?)-cocaine, as compared to wild-type BChE. Pharmaceutical compositions of the presently-disclosed subject matter include a BChE polypeptide variant having an enhanced catalytic efficiency for (?)-cocaine. A method of the presently-disclosed subject matter for treating a cocaine-induced condition includes administering to an individual an effective amount of a BChE polypeptide variant, as disclosed herein, to lower blood cocaine concentration.

Abstract: A ventilation air pressure oscillation mitigation device for a ventilator includes a housing defining an inlet and an outlet. The device includes a valve seat defining a primary opening and a plurality of secondary openings. A valve body is selectively positionable in a first position and a second position within the device. In the first position, substantially all of a first flow of ventilation air from the inlet to the outlet passes through the primary opening. When the valve body is in the second position, all of a second flow of ventilation air from the inlet to the outlet passes through the plurality of secondary openings. An actuator controls a position of the valve body.

Abstract: The present invention relates to a method for modeling a common-language speech recognition, by a computer, under the influence of multiple dialects and concerns a technical field of speech recognition by a computer. In this method, a triphone standard common-language model is first generated based on training data of standard common language, and first and second monophone dialectal-accented common-language models are based on development data of dialectal-accented common languages of first kind and second kind, respectively. Then a temporary merged model is obtained in a manner that the first dialectal-accented common-language model is merged into the standard common-language model according to a first confusion matrix obtained by recognizing the development data of first dialectal-accented common language using the standard common-language model.

Abstract: Butyrylcholinesterase (BChE) polypeptide variants of the presently-disclosed subject matter have enhanced catalytic efficiency for (?)-cocaine, as compared to wild-type BChE. Pharmaceutical compositions of the presently-disclosed subject matter include a BChE polypeptide variant having an enhanced catalytic efficiency for (?)-cocaine. A method of the presently-disclosed subject matter for treating a cocaine-induced condition includes administering to an individual an effective amount of a BChE polypeptide variant, as disclosed herein, to lower blood cocaine concentration.

Abstract: One or more test features are extracted from a time domain signal. The test features are represented by discrete data. The discrete data is represented for each of the one or more test features by a corresponding one or more fitting functions, which are defined in terms of finite number of continuous basis functions and a corresponding finite number of expansion coefficients. Each fitting function is compressed through Functional Principal Component Analysis (FPCA) to generate corresponding sets of principal components. Each principal component for a given test feature is uncorrelated to each other principal component for the given test feature. A distance between a set of principal components for the given test feature and a set of principal components for one or more training features with the processing system is calculated. The test feature is classified according to the distance calculated with the processing system.

Abstract: Butyrylcholinesterase (BChE) polypeptide variants of the presently-disclosed subject matter have enhanced catalytic efficiency for (?)-cocaine, as compared to wild-type BChE. Pharmaceutical compositions of the presently-disclosed subject matter include a BChE polypeptide variant having an enhanced catalytic efficiency for (?)-cocaine. A method of the presently-disclosed subject matter for treating a cocaine-induced condition includes administering to an individual an effective amount of a BChE polypeptide variant, as disclosed herein, to lower blood cocaine concentration.

Abstract: Butyrylcholinesterase (BChE) polypeptide variants of the presently-disclosed subject matter have enhanced catalytic efficiency for (?)-cocaine, as compared to wild-type BChE. Pharmaceutical compositions of the presently-disclosed subject matter include a BChE polypeptide variant having an enhanced catalytic efficiency for (?)-cocaine. A method of the presently-disclosed subject matter for treating a cocaine-induced condition includes administering to an individual an effective amount of a BChE polypeptide variant, as disclosed herein, to lower blood cocaine concentration.

Abstract: A method for preventing the loss of information within a speech frame is described. A first speech frame to be encoded is selected. A determination is made as to whether or not a second speech frame is a critical speech frame based on the information within the second speech frame and one or more adjacent speech frames. At least a part of an encoded version of the second speech frame is created according to a selected forward error correction (FEC) mode if the second speech frame is a critical speech frame. The first speech frame and the at least a part of the encoded version of the second speech frame are transmitted.

Abstract: Butyrylcholinesterase (BChE) polypeptide variants of the presently-disclosed subject matter have enhanced catalytic efficiency for (?)-cocaine, as compared to wild-type BChE. Pharmaceutical compositions of the presently-disclosed subject matter include a BChE polypeptide variant having an enhanced catalytic efficiency for (?)-cocaine. A method of the presently-disclosed subject matter for treating a cocaine-induced condition includes administering to an individual an effective amount of a BChE polypeptide variant, as disclosed herein, to lower blood cocaine concentration.

Abstract: The present invention relates to a method for modeling a common-language speech recognition, by a computer, under the influence of multiple dialects and concerns a technical field of speech recognition by a computer. In this method, a triphone standard common-language model is first generated based on training data of standard common language, and first and second monophone dialectal-accented common-language models are based on development data of dialectal-accented common languages of first kind and second kind, respectively. Then a temporary merged model is obtained in a manner that the first dialectal-accented common-language model is merged into the standard common-language model according to a first confusion matrix obtained by recognizing the development data of first dialectal-accented common language using the standard common-language model.

Abstract: A reciprocating drive apparatus has a driving device and a driven device, one of the devices comprising a reciprocating member mounted for movement along a longitudinal axis. At least one rotary member is coupled to one of the devices and a linear bearing assembly has a linear guide rail and a linear slide member with an end coupled to the other device. A connecting link has a first end pivotally connected to the rotary member and a second end pivotally linked to the slide member. Where the reciprocating member is the driven device, rotation of the rotary member will cause the reciprocating member to move back and forth along the longitudinal axis.

Abstract: A WDM optical transmit-receive device comprises an optical transceiver assembly and an optical receiver assembly. The optical transceiver assembly includes a first optical platform, a first optical filter, a first photodetector and a laser diode, where the first optical platform has a first surface and a first groove recessed from the first surface, the first optical filter is inserted into the first groove, the first photodetector and the laser diode are mounted adjacent to the first optical filter.