Patents by Inventor Fangming Kong

Fangming Kong has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biologically active peptides and compositions, their use
    Patent number: 7772397
    Abstract: This invention relates to derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by general formula I, wherein Y, n, R1, R2, R3, R6, R7, R70, R71, R72, R74, and R75 are as defined in the specification.
    Type: Grant
    Filed: July 21, 2008
    Date of Patent: August 10, 2010
    Assignee: University of British Columbia
    Inventors: Raymond Andersen, John Coleman, Dilip De Silva, Fangming Kong, Edward Piers, Debra Wallace, Michel Roberge, Theresa Allen
  • BIOLOGICALLY ACTIVE PEPTIDES AND COMPOSITIONS, THEIR USE
    Publication number: 20090088573
    Abstract: This invention relates to derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by general formula I, wherein Y, n, R1, R2, R3, R6, R7, R70, R71, R72, R74, and R75 are as defined in the specification.
    Type: Application
    Filed: July 21, 2008
    Publication date: April 2, 2009
    Applicant: The University of British Columbia
    Inventors: Raymond ANDERSEN, John Coleman, Dilip De Silva, Fangming Kong, Edward Piers, Debra Wallace, Michel Roberge, Theresa Allen
  • 6-carboxy-normorphinan derivatives, synthesis and uses thereof
    Patent number: 7501434
    Abstract: The present invention relates to compounds of formula I, synthesis thereof, and methods of using the same.
    Type: Grant
    Filed: August 3, 2007
    Date of Patent: March 10, 2009
    Assignee: Wyeth
    Inventors: Syed M. Shah, Kadum A. Ali, FangMing Kong, Tianmin Zhu, Charles T. Gombar
  • Biologically active peptides and compositions, their use
    Patent number: 7410951
    Abstract: Derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by formula I wherein Y, n, R1, R2, R3, R7, R70, R71, R72, R74, and R75 are as defined in the specification.
    Type: Grant
    Filed: January 14, 2005
    Date of Patent: August 12, 2008
    Assignee: The University of British Columbia
    Inventors: Raymond Andersen, John Coleman, Dilip De Silva, Fangming Kong, Edward Piers, Debra Wallace, Michel Roberge, Theresa Allen
  • 6-Carboxy-normorphinan derivatives, synthesis and uses thereof
    Publication number: 20080064744
    Abstract: The present invention relates to compounds of formula I, synthesis thereof, and methods of using the same.
    Type: Application
    Filed: August 3, 2007
    Publication date: March 13, 2008
    Applicant: Wyeth
    Inventors: Syed Shah, Kadum Ali, FangMing Kong, Tianmin Zhu, Charles Gombar
  • Antibiotics AW998A, AW998B, AW998C and AW998D
    Patent number: 7018996
    Abstract: This invention relates to antibiotics selected from the group AW998A, AW998B, AW998C and AW998D derived from the microorganism Streptomyces designated LL-AW998, which are useful as antibacterial agents.
    Type: Grant
    Filed: July 11, 2003
    Date of Patent: March 28, 2006
    Assignee: Wyeth Holdings Corporation
    Inventors: Fangming Kong, Guy Thomas Carter, Scott William Luckman
  • Biologically active peptides and compositions, their use
    Publication number: 20050171137
    Abstract: This invention relates to derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by general formula I, wherein Y, n, R1, R2, R3, R6, R7, R70, R71, R72, R74, and R75 are as defined in the specification.
    Type: Application
    Filed: January 14, 2005
    Publication date: August 4, 2005
    Inventors: Raymond Andersen, John Coleman, Dilip De Silva, Fangming Kong, Edward Piers, Debra Wallace, Michael Roberge, Teresa Allen
  • Glycopeptide antibiotics
    Patent number: 6914045
    Abstract: The invention provides compounds of formula Wherein R1, R2, R3, R4, R5, R6a, R6b, R6c, R6d, R6e and R7 are defined in the specification. These compounds are useful as antibiotic agents.
    Type: Grant
    Filed: April 25, 2002
    Date of Patent: July 5, 2005
    Assignee: Wyeth Holdings Corporation
    Inventors: Darren Robert Abbanat, Valerie Sue Bernan, Russell George Dushin, Michael Greenstein, Haiyin He, Stanley Albert Lang, Howard Newman, Subas Sakya, Phaik-Eng Sum, Alan Gordon Sutherland, Ting-Zhong Wang, Jason Arnold Lotvin, Mark Edward Ruppen, Arthur Emergy Bailey, Ping Cai, Bo Shen, Fangming Kong
  • Biologically active peptides and compositions, their use
    Patent number: 6870028
    Abstract: This invention relates to derivatives of hemiasterlin or Geodiamolide G having anti-mitotic activities and useful in treating cancer. These derivatives are represented by general formula I, wherein Y, n, R1, R2, R3, R6, R7, R70, R71, R72, R74, and R75 are as defined in the specification.
    Type: Grant
    Filed: June 14, 2000
    Date of Patent: March 22, 2005
    Assignees: University of British Columbia, University of Alberta
    Inventors: Raymond Andersen, John Coleman, Dilip De Silva, Fangming Kong, Edward Piers, Debra Wallace, Michael Roberge, Theresa Allen
  • Antifungal antibiotics
    Publication number: 20040138302
    Abstract: This disclosure describes antifungal antibiotics designated Hygroscopene A, Hygroscopene B and Hygroscopene C to their production by fermentation, to methods for recovery and concentration from the crude solutions, to a process for purification and to new analogs of Hygroscopene A, Hygroscopene B and Hygroscopene C prepared by synthetic procedures.
    Type: Application
    Filed: December 18, 2003
    Publication date: July 15, 2004
    Applicant: Wyeth Holdings Corporation
    Inventors: Ping Cai, Fangming Kong, Pamela Fink Charbonneau, Mark Edward Ruppen
  • Antibiotics AW998A, AW998B, AW998C and AW998D
    Publication number: 20040014646
    Abstract: This invention relates to antibiotics selected from the group AW998A, AW998B, AW998C and AW998D derived from the microorganism Streptomyces designated LL-AW998, which are useful as antibacterial agents.
    Type: Application
    Filed: July 11, 2003
    Publication date: January 22, 2004
    Applicant: Wyeth Holdings Corporation
    Inventors: Fangming Kong, Guy Thomas Carter, Scott William Luckman
  • Estrenes
    Patent number: 6649779
    Abstract: This invention provides a pharmaceutically acceptable salt of 3&bgr;-hydroxy-5(10)-estrene-17-one 3-sulfate ester and a pharmaceutically acceptable salt of 3&agr;-hydroxy-5(10)-estrene-17-one 3-sulfate ester, which are useful as an estrogens.
    Type: Grant
    Filed: June 5, 2002
    Date of Patent: November 18, 2003
    Assignee: Wyeth
    Inventors: Michael Z. Kagan, Fangming Kong, Leonard A. McDonald, Panolil Raveendranath, Syed M. Shah, Joseph Zeldis
  • Glycopeptide antibiotics
    Publication number: 20030087812
    Abstract: The invention provides compounds of formula 1
    Type: Application
    Filed: April 25, 2002
    Publication date: May 8, 2003
    Applicant: American Cyanamid Company
    Inventors: Darren Robert Abbanat, Valerie Sue Bernan, Russell George Dushin, Michael Greenstein, Haiyin He, Stanley Albert Lang, Howard Newman, Subas Sakya, Phaik-Eng Sum, Alan Gordon Sutherland, Ting-Zhong Wang, Jason Arnold Lotvin, Mark Edward Ruppen, Arthur Emery Bailey, Ping Cai, Bo Shen, Fangming Kong
  • Estrenes
    Publication number: 20020151532
    Abstract: This invention provides a pharmaceutically acceptable salt of 3&bgr;-hydroxy-5(10)-estrene-17-one 3-sulfate ester and a pharmaceutically acceptable salt of 3&agr;-hydroxy-5(10)-estrene-17-one 3-sulfate ester, which are useful as an estrogens.
    Type: Application
    Filed: June 5, 2002
    Publication date: October 17, 2002
    Applicant: Wyeth
    Inventors: Michael Z. Kagan, Fangming Kong, Leonard A. McDonald, Panolil Raveendranath, Syed M. Shah, Joseph Zeldis
  • Estradienes
    Patent number: 6458778
    Abstract: This invention provides estra-5(10),7-dien-3&bgr;-ol-17-one or a pharmaceutically acceptable salt of its 3-sulfate ester, estra-5(10),7-dien-3&bgr;-ol-17-one 3-glucuronide or a pharmaceutically acceptable salt thereof, estra-5(10),7-dien-3&agr;-ol-17-one or a pharmaceutically acceptable salt of its 3-sulfate ester, estra-5(10),7-dien-3&bgr;-ol-17-one 3-glucuronide or a pharmaceutically acceptable salt thereof, estra-5(10),7-dien-3&bgr;-ol-17-one 3-alkali metal salt, and estra-5(10),7-dien-3&agr;-ol-17-one 3-alkali metal salt which are useful as estrogenic agents.
    Type: Grant
    Filed: March 27, 1998
    Date of Patent: October 1, 2002
    Assignee: Wyeth
    Inventors: Fangming Kong, Leonard A. McDonald, Michael Z. Kagan, Syed M. Shah, Panolil Raveendranath, Mark A. Collins
  • Biologically active peptides and compositions, their use
    Patent number: 6153590
    Abstract: Compounds of general formula I ##STR1## wherein: R.sub.1 and R.sub.70 independently represent a hydrogen atom or an optionally substituted alkyl or acyl group; R.sub.2 represents a hydrogen atom or an optionally substituted alkyl or acyl group or is absent when R.sub.6 represents a group --CH.dbd. as hereinafter described; R.sub.73 represents a hydrogen atom or an optional substituent or is absent when R.sub.6 represents a methylene group or a group --CH.dbd. as hereinafter described; Y represents an optional substituent; n represents 0, 1, 2, 3, or 4; R.sub.3 represents a hydrogen atom, or an optionally substituted alkyl group; R.sub.74 represents a hydrogen atom, a hydroxy group or an optionally substituted alkyl or acyl group; R.sub.7 represents a hydrogen atom or an alkyl group; R.sub.75 represents an optionally substituted alkyl group; and i) R.sub.6 and R.sub.71 independently represent a hydrogen atom or an optionally substituted alkyl or acyl group; and R.sub.72 represents a hydrogen atom; or ii) R.
    Type: Grant
    Filed: February 2, 1998
    Date of Patent: November 28, 2000
    Assignees: University of Alberta, University of British Columbia
    Inventors: Raymond Andersen, John Coleman, Dilip De Silva, Fangming Kong, Edward Piers, Debra Wallace, Michel Roberge, Teresa Allen