Abstract: Provided is a dual-agonist compound for both Glucagon-like Peptide-1 (GLP-1) and Glucose-dependent Insulinotropic Polypeptide (GIP) receptors and application thereof. In particular, provided are a polypeptide analog derived from GLP-1 and a pharmaceutically acceptable salt thereof, which has an agonist effect on human GLP-1 receptor and human GIP receptor and can be used for the treatment of metabolic diseases such as obesity, type II diabetes, and non-alcoholic fatty liver.

Abstract: Provided are a calcium-sensing receptor (CaSR) agonist compound and application thereof. Specifically, provided are a series of polypeptide CaSR agonist compounds and pharmaceutically acceptable salts thereof, which have agonist effects on human CaSRs to reduce plasma parathyroid hormone and serum calcium ion levels, and can be used for treatment of metabolic diseases such as primary hyperparathyroidism, secondary hyperparathyroidism, and tumor-induced hypercalcemia.

Abstract: A series of pharmaceutical compositions containing polypeptide dual agonist compounds and pharmaceutically acceptable salts thereof, wherein same have dual agonist effects on a human glucagon-like peptide-1 (GLP-1) receptor and a human blood glucose-dependent insulinotropic polypeptide (GIP) receptor, and can be used for treating non-insulin-dependent diabetes, insulin-dependent diabetes, obesity and other related diseases.

Abstract: A wireless sensor network deployment structure combined with SFFT and COA and a frequency spectrum reconstruction method therefor. The wireless sensor network deployment structure includes: frequency spectrum acquisition sensor nodes dispersed in each region, and a sink node, wherein all the frequency spectrum acquisition sensor nodes have the same structure, and include: a broadband frequency spectrum antenna, a delayer, an ADC, a first baseband processing module, a DAC and a transmitting antenna that are successively connected; all the frequency spectrum acquisition sensor nodes are cooperated to realize SFFT and COA of signals; the signals transmitted by all the frequency spectrum acquisition sensor nodes are superimposed over the air and received by the sink node; and the sink node extracts a data domain from a received signal frame by post-processing, thereby completing frequency spectrum reconstruction.

Abstract: A wireless sensor network deployment structure combined with SFFT and COA and a frequency spectrum reconstruction method therefor. The wireless sensor network deployment structure includes: frequency spectrum acquisition sensor nodes dispersed in each region, and a sink node, wherein all the frequency spectrum acquisition sensor nodes have the same structure, and include: a broadband frequency spectrum antenna, a delayer, an ADC, a first baseband processing module, a DAC and a transmitting antenna that are successively connected; all the frequency spectrum acquisition sensor nodes are cooperated to realize SFFT and COA of signals; the signals transmitted by all the frequency spectrum acquisition sensor nodes are superimposed over the air and received by the sink node; and the sink node extracts a data domain from a received signal frame by post-processing, thereby completing frequency spectrum reconstruction.