Patents by Inventor Fanyi Zeng

Fanyi Zeng has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10883082
    Abstract: The present invention includes methods for effecting phenotype conversion in a cell by transfecting the cell with phenotype-converting nucleic acid. Expression of the nucleic acids results in a phenotype conversion in the transfected cell. Preferably the phenotype-converting nucleic acid is a transcriptome, and more preferably an mRNA transcriptome.
    Type: Grant
    Filed: March 31, 2014
    Date of Patent: January 5, 2021
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: James Eberwine, Jai-Yoon Sul, Chia-Wen Wu, Fanyi Zeng, Junhyong Kim
  • Publication number: 20200270633
    Abstract: The present invention includes methods for effecting phenotype conversion in a cell by transfecting the cell with phenotype-converting nucleic acid. Expression of the nucleic acids results in a phenotype conversion in the transfected cell. Preferably the phenotype-converting nucleic acid is a transcriptome, and more preferably an mRNA transcriptome.
    Type: Application
    Filed: May 11, 2020
    Publication date: August 27, 2020
    Inventors: James Eberwine, Jai-Yoon Sul, Chia-Wen Wu, Fanyi Zeng, Junhyong Kim
  • Publication number: 20200206364
    Abstract: The present invention includes methods for transferring a multigenic phenotype to a cell by transfecting, preferably by phototransfection, and locally transfecting a cell or a cellular process with a laser while the cell is bathed in a fluid medium comprising two or more nucleic acids, thereby introducing the nucleic acid into the interior of the cell. Expression of the nucleic acids results in a multigenic phenotype in the transfected cell.
    Type: Application
    Filed: March 10, 2020
    Publication date: July 2, 2020
    Inventors: James Eberwine, Philip G. Haydon, Jai-Yoon Sul, Hajime Takano, Chia-Wen Kitty Wu, Fanyi Zeng
  • Patent number: 10647960
    Abstract: The present invention includes methods for effecting phenotype conversion in a cell by transfecting the cell with phenotype-converting nucleic acid. Expression of the nucleic acids results in a phenotype conversion in the transfected cell. Preferably the phenotype-converting nucleic acid is a transcriptome, and more preferably an mRNA transcriptome.
    Type: Grant
    Filed: April 6, 2010
    Date of Patent: May 12, 2020
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: James Eberwine, Jai-Yoon Sul, Chia-Wen Wu, Fanyi Zeng, Junhyong Kim
  • Patent number: 10646590
    Abstract: The present invention includes methods for transferring a multigenic phenotype to a cell by transfecting, preferably by phototransfection, and locally transfecting a cell or a cellular process with a laser while the cell is bathed in a fluid medium comprising two or more nucleic acids, thereby introducing the nucleic acid into the interior of the cell. Expression of the nucleic acids results in a multigenic phenotype in the transfected cell.
    Type: Grant
    Filed: December 12, 2006
    Date of Patent: May 12, 2020
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: James Eberwine, Philip G. Haydon, Jai-Yoon Sul, Hajime Takano, Chia-Wen Kitty Wu, Fanyi Zeng
  • Patent number: 10583204
    Abstract: The present invention includes methods for transferring a multigenic phenotype to a cell by transfecting, preferably by phototransfection, and locally transfecting a cell or a cellular process with a laser while the cell is bathed in a fluid medium comprising two or more nucleic acids, thereby introducing the nucleic acid into the interior of the cell. Expression of the nucleic acids results in a multigenic phenotype in the tranfected cell.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: March 10, 2020
    Assignee: THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
    Inventors: James Eberwine, Philip G. Haydon, Jai-Yoon Sul, Hajime Takano, Chia-Wen Kitty Wu, Fanyi Zeng
  • Publication number: 20170364572
    Abstract: Disclosed herein is a data synchronization between a client computing device's local store and another data store, such as a data store that is remote to the client computing device. The other data store may comprise a cloud data store. The existence, or absence, of a causal relationship between the local and remote data stores for a given data item is used to determine whether or not a conflict exists and/or whether a requested operation may be performed. The casual relationship may be determined using a previous commit's hash value, referred to as a hash_base value, and a hash value, both of which are associated with the data item.
    Type: Application
    Filed: September 3, 2017
    Publication date: December 21, 2017
    Inventors: Ric ALLINSON, Fanyi ZENG
  • Patent number: 9754002
    Abstract: Disclosed herein is a data synchronization between a client computing device's local store and another data store, such as a data store that is remote to the client computing device. The other data store may comprise a cloud data store. The existence, or absence, of a causal relationship between the local and remote data stores for a given data item is used to determine whether or not a conflict exists and/or whether a requested operation may be performed. The causal relationship may be determined using a previous commit's hash value, referred to as a hash_base value, and a hash value, both of which are associated with the data item.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: September 5, 2017
    Assignee: EXCALIBUR IP, LLC
    Inventors: Ric Allinson, Fanyi Zeng
  • Publication number: 20170169086
    Abstract: Disclosed herein is a data synchronization between a client computing device's local store and another data store, such as a data store that is remote to the client computing device. The other data store may comprise a cloud data store. The existence, or absence, of a causal relationship between the local and remote data stores for a given data item is used to determine whether or not a conflict exists and/or whether a requested operation may be performed. The causal relationship may be determined using a previous commit's hash value, referred to as a hash_base value, and a hash value, both of which are associated with the data item.
    Type: Application
    Filed: February 26, 2017
    Publication date: June 15, 2017
    Inventors: Ric ALLINSON, Fanyi ZENG
  • Publication number: 20160098469
    Abstract: Disclosed herein is a data synchronization between a client computing device's local store and another data store, such as a data store that is remote to the client computing device. The other data store may comprise a cloud data store. The existence, or absence, of a causal relationship between the local and remote data stores for a given data item is used to determine whether or not a conflict exists and/or whether a requested operation may be performed. The causal relationship may be determined using a previous commit's hash value, referred to as a hash_base value, and a hash value, both of which are associated with the data item.
    Type: Application
    Filed: October 7, 2014
    Publication date: April 7, 2016
    Inventors: Ric Allinson, Fanyi Zeng
  • Publication number: 20140206059
    Abstract: The present invention includes methods for effecting phenotype conversion in a cell by transfecting the cell with phenotype-converting nucleic acid. Expression of the nucleic acids results in a phenotype conversion in the transfected cell. Preferably the phenotype-converting nucleic acid is a transcriptome, and more preferably an mRNA transcriptome.
    Type: Application
    Filed: March 31, 2014
    Publication date: July 24, 2014
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: James Eberwine, Jai-Yoon Sul, Chia-Wen Wu, Fanyi Zeng, Junhyong Kim
  • Publication number: 20120178167
    Abstract: The present invention includes methods for transferring a multigenic phenotype to a cell by transfecting, preferably by phototransfection, and locally transfecting a cell or a cellular process with a laser while the cell is bathed in a fluid medium comprising two or more nucleic acids, thereby introducing the nucleic acid into the interior of the cell. Expression of the nucleic acids results in a multigenic phenotype in the tranfected cell.
    Type: Application
    Filed: March 21, 2012
    Publication date: July 12, 2012
    Inventors: James Eberwine, Philip G. Haydon, Jai-Yoon Sul, Hajime Takano, Chia-Wen Kitty Wu, Fanyi Zeng
  • Publication number: 20120135493
    Abstract: The present invention includes methods for transferring a multigenic phenotype to a cell by transfecting, preferably by phototransfection, and locally transfecting a cell or a cellular process with a laser while the cell is bathed in a fluid medium comprising two or more nucleic acids, thereby introducing the nucleic acid into the interior of the cell. Expression of the nucleic acids results in a multigenic phenotype in the tranfected cell.
    Type: Application
    Filed: December 12, 2006
    Publication date: May 31, 2012
    Inventors: James Eberwine, Philip G. Haydon, Jai-Yoon Sul, Hajime Takano, Chia-Wen Kitty Wu, Fanyi Zeng
  • Publication number: 20110033934
    Abstract: The present invention includes methods for effecting phenotype conversion in a cell by transfecting the cell with phenotype-converting nucleic acid. Expression of the nucleic acids results in a phenotype conversion in the transfected cell. Preferably the phenotype-converting nucleic acid is a transcriptome, and more preferably an mRNA transcriptome.
    Type: Application
    Filed: April 6, 2010
    Publication date: February 10, 2011
    Inventors: James Eberwine, Jai-Yoon Sul, Chia-Wen Wu, Fanyi Zeng, Junhyong Kim
  • Publication number: 20030096410
    Abstract: Fresh human hematopietic stem cells (HSC) obtained from umbilical cord blood, bone marrow, liver or other human tissues are directly injected into peritoneal cavity of fetal goat at 45-55 day gestation age under B-type ultrasonographic scan. Human HSC expands for up to 1000-10,000 fold in circulatory blood of recipient goats and the human HSC phenotype with non-differentiation remains stable up to over 10 months. The human cells can also grow and propagate in liver and other tissues of the recipient goats. The stored stem cells can be used for disease treatment, organ transplantation and in vivo assays of drugs.
    Type: Application
    Filed: June 24, 2002
    Publication date: May 22, 2003
    Inventors: Fanyi Zeng, Shu-zhen Huang, Yi-Tao Zeng