Patents by Inventor Fanyuan Yu

Fanyuan Yu has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Polypeptide and application thereof in bone repair
    Patent number: 11912793
    Abstract: A polypeptide and an application thereof in bone repair are provided. An amino acid sequence of the polypeptide provided by the invention is shown as SEQ ID NO: 1. The invention further discloses use of the polypeptide GS18 in bone injury and/or bone repair. Furthermore, the invention further discloses an application of the polypeptide GS18 as well as a polypeptide scaffold for bone repair. The polypeptide of the invention demonstrates the ability to translocate ?-catenin into the nucleus and induce the expression of secreted protein osteocalcin in vivo. In vitro, the polypeptide facilitates the osteogenic differentiation of osteogenesis-oriented BMSCs (pre-osteoblasts thereby promoting the process of bone repair.
    Type: Grant
    Filed: April 28, 2023
    Date of Patent: February 27, 2024
    Assignee: SICHUAN UNIVERSITY
    Inventors: Ling Ye, Fanyuan Yu, Jiayi Wu, Feifei Li
  • POLYPEPTIDE AND APPLICATION THEREOF IN BONE REPAIR
    Publication number: 20230357321
    Abstract: A polypeptide and an application thereof in bone repair are provided. An amino acid sequence of the polypeptide provided by the invention is shown as SEQ ID NO: 1. The invention further discloses use of the polypeptide GS18 in bone injury and/or bone repair. Furthermore, the invention further discloses an application of the polypeptide GS18 as well as a polypeptide scaffold for bone repair. The polypeptide of the invention demonstrates the ability to translocate ?-catenin into the nucleus and induce the expression of secreted protein osteocalcin in vivo. In vitro, the polypeptide facilitates the osteogenic differentiation of osteogenesis-oriented BMSCs (pre-osteoblasts thereby promoting the process of bone repair.
    Type: Application
    Filed: April 28, 2023
    Publication date: November 9, 2023
    Applicant: SICHUAN UNIVERSITY
    Inventors: Ling Ye, Fanyuan Yu, Jiayi Wu, Feifei Li